Hiroshi Kondo

Profile Information

Affiliation: Kyoto University

J-GLOBAL ID: 201401003860380827
researchmap Member ID: 7000008603

Research Areas

Life sciences / Internal medicine - General /

Papers

RNA-binding proteins: Underestimated contributors in tumorigenesis

Y. Zhao, C. Mir, Y. Garcia-Mayea, R. Paciucci, H. Kondoh, M.E. LLeonart

Seminars in Cancer Biology, Feb, 2022
Reply to Zheng et al.: Clinical metabolomics: Detailed analysis by nontargeted method is complementary to large-scale studies

Hiroshi Kondoh, Takayuki Teruya, Yung-Ju Chen, Yasuhide Fukuji, Mitsuhiro Yanagida

Proceedings of the National Academy of Sciences, 119(5), Feb, 2022
Decline of ergothioneine in frailty and cognition impairment.

Hiroshi Kondoh, Takayuki Teruya, Masahiro Kameda, Mitsuhiro Yanagida

FEBS letters, Jan 28, 2022
Targeting p21 for diabetes: Another choice of senotherapy

Hiroshi Kondoh, Eiji Hara

Cell Metabolism, 34(1) 5-7, Jan, 2022
Cellular Aging and Metabolites in Aging

Hiroshi Kondoh, Takumi Mikawa, Masahiro Kameda

Aging Mechanisms II, 77-95, 2022
Cellular Senescence in Diabetes Mellitus: Distinct Senotherapeutic Strategies for Adipose Tissue and Pancreatic β Cells.

Takaaki Murakami, Nobuya Inagaki, Hiroshi Kondoh

Frontiers in endocrinology, 13 869414-869414, 2022
Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer

Rumi Itoyama, Noriko Yasuda-Yoshihara, Fumimasa Kitamura, Tadahito Yasuda, Luke Bu, Atsuko Yonemura, Tomoyuki Uchihara, Kota Arima, Xichen Hu, Zhang Jun …

Cancer Letters, 523 29-42, Dec, 2021
Whole-blood metabolomics of dementia patients reveal classes of disease-linked metabolites

Takayuki Teruya, Yung-Ju Chen, Hiroshi Kondoh, Yasuhide Fukuji, Mitsuhiro Yanagida

Proceedings of the National Academy of Sciences, 118(37), Sep 14, 2021
Reduced uremic metabolites are prominent feature of sarcopenia, distinct from antioxidative markers for frailty

Masahiro Kameda, Takayuki Teruya, Mitsuhiro Yanagida, Hiroshi Kondoh

Aging, Sep 7, 2021
Characterization of genetically modified mice for phosphoglycerate mutase, a vitally-essential enzyme in glycolysis

Takumi Mikawa, Eri Shibata, Midori Shimada, Ken Ito, Tomiko Ito, Hiroaki Kanda, Keiyo Takubo, Atsuyoshi Shimada, Matilde E. Lleonart, Nobuya Inagaki …

PLOS ONE, 16(4) e0250856-e0250856, Apr 29, 2021
Editorial: How Do Metabolism, Angiogenesis, and Hypoxia Modulate Resistance?

Hiroshi Kondoh, Josep Castellvi, Matilde Esther LLeonart

Frontiers in Oncology, 11, Apr 12, 2021
Senescence research from historical theory to future clinical application

Masahiro Kameda, Takumi Mikawa, Masayuki Yokode, Nobuya Inagaki, Hiroshi Kondoh

Geriatrics & Gerontology International, 21(2) 125-130, Feb, 2021
Reply to Pan et al.: Whole blood metabolome analysis combined with comprehensive frailty assessment

Masahiro Kameda, Takayuki Teruya, Mitsuhiro Yanagida, Hiroshi Kondoh

Proceedings of the National Academy of Sciences, 118(1) e2016640118-e2016640118, Jan 5, 2021
Efficient and rapid assessment of multiple aspects of frailty using the Kyoto Frailty Scale, developed from the Edmonton Frail Scale

Masahiro Kameda, Rie Shibata, Hiroshi Kondoh

Journal of Physical Therapy Science, 33(3) 267-273, 2021
Whole Blood Metabolomics in Aging Research

Hiroshi Kondoh, Masahiro Kameda, Mitsuhiro Yanagida

International Journal of Molecular Sciences, 22(1) 175-175, Dec 26, 2020
T cell-specific deletion of Pgam1 reveals a critical role for glycolysis in T cell responses

Koji Toriyama, Makoto Kuwahara, Hiroshi Kondoh, Takumi Mikawa, Nobuaki Takemori, Amane Konishi, Toshihiro Yorozuya, Takeshi Yamada, Tomoyoshi Soga, Atsushi Shiraishi …

Communications Biology, 3(1), Dec, 2020
Autophagy Takes Center Stage as a Possible Cancer Hallmark

Jose G. Alvarez-Meythaler, Yoelsis Garcia-Mayea, Cristina Mir, Hiroshi Kondoh, Matilde E. LLeonart

Frontiers in Oncology, 10, Oct 22, 2020
Metabolomics of human fasting: new insights about old questions

Hiroshi Kondoh, Takayuki Teruya, Mitsuhiro Yanagida

Open Biology, 10(9) 200176-200176, Sep, 2020
Phosphoglycerate Mutase Cooperates with Chk1 Kinase to Regulate Glycolysis

Takumi Mikawa, Eri Shibata, Midori Shimada, Ken Ito, Tomiko Ito, Hiroaki Kanda, Keiyo Takubo, Matilde E. Lleonart, Nobuya Inagaki, Masayuki Yokode …

iScience, 23(7) 101306-101306, Jul, 2020 Peer-reviewed
Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility

Masahiro Kameda, Takayuki Teruya, Mitsuhiro Yanagida, Hiroshi Kondoh

Proceedings of the National Academy of Sciences, 117(17) 9483-9489, Apr 28, 2020

Misc.

Senescence-inducing stress and glycolytic enzyme, PGAM

Hiroshi Kondoh, Takumi Mikawa, Nobuya Inagaki

Seikagaku, 88(3) 296-301, 2016
経腸栄養下DRV投与が有効であった食道瘻を伴う粟粒結核合併AIDSの一例

水野菜穂子, 小林正行, 原島伸一, 近藤祥司, 尾崎淳子, 辻秀美, 幣憲一郎, 稲垣暢也, 高折晃史

日本エイズ学会誌, 17(4) 497-497, Nov 20, 2015
Disruptive chemicals, senescence and immortality

Amancio Carnero, Carmen Blanco-Aparicio, Hiroshi Kondoh, Matilde E. Lleonart, Juan Fernando Martinez-Leal, Chiara Mondello, A. Ivana Scovassi, William H. Bisson, Amedeo Amedei, Rabindra Roy …

CARCINOGENESIS, 36 S19-S37, Jun, 2015
ES細胞増殖に必須な代謝特性としての解糖系代謝亢進

KONDO HIROSHI, NAKASHIMA YASUHIRO, MARUYAMA TAKESHI, TANAKA MAKOTO, YOKODE MASAYUKI

再生医療, 7(2) 165-170, May 1, 2008

Books and Other Publications

老化生物学老いと寿命のメカニズム

近藤祥司 (Role: Supervisor (editorial), 全390ページ)

MEDSI, Aug, 2015
シリーズ進化生物学の新潮流；老化という生存戦略；進化におけるトレードオフ

近藤祥司

日本評論社, Jul, 2015
老化はなぜ進むのか

近藤祥司

講談社ブルーバックス, Dec 20, 2009

Presentations

老化・加齢性疾患に関連するメタボライトや解糖系代謝機構の解明

近藤祥司

先端モデル動物⽀援プラットフォーム成果発表会, Feb 2, 2021
老化や加齢性疾患関連メタボライトと解糖系代謝機構の同定

近藤祥司

日本分子生物学会, Dec 3, 2020
網羅的全血メタボローム解析による新規フレイルマーカーの発見

近藤祥司

日本老年医学会近畿地方会, Nov 21, 2020
簡易版京都フレイルスクリーニングスケール「KFS」の有用性

近藤祥司

日本老年医学会近畿地方会, Nov 21, 2020
PGAM の「非酵素機能」によるワールブルグ解糖系新規制御機構

近藤祥司

日本抗加齢医学会, Sep 25, 2020
網羅的全血メタボローム解析による新規フレイルマーカーの発見

近藤祥司

日本老年医学会, Aug 5, 2020
網羅的全血メタボロームによる老化研究

近藤祥司

第43回日本基礎老化学会大会, May 10, 2020
網羅的全血メタボローム解析による新規フレイルマーカーの発見

近藤祥司

先端動物モデル成果発表会, Jan 31, 2020
解糖系酵素PGAMによる新規解糖系制御機構

三河拓己, 近藤祥司

第30回日本老年医学会近畿地方会, Nov 16, 2019
Identification of the metabolites and glycolytic regulation involved in ageing and its relevant diseases.

France-Japan workshop, Sep 6, 2019 Invited
ヒト絶食による代謝シフトの網羅的解析

近藤祥司

日本老年医学会, Jun 8, 2019
老化の多様性を規定する解糖系代謝恒常性の維持・変容・破綻による病態の解明

近藤祥司

第61回日本老年医学会, Jun 6, 2019
ワールブルグ解糖系代謝の新規分子制御メカニズムの解明

近藤祥司

先端動物モデル成果発表会, Jan 31, 2019
ヒト絶食による代謝シフトの網羅的解析

近藤祥司

日本老年医学会近畿地方会, Nov 17, 2018
老化・癌化におけるメタボライトと解糖系代謝研究

近藤祥司

第60回日本老年医学会, Jun 14, 2018
解糖系代謝新規制御機構の解明

近藤祥司

先端モデル動物支援プラットフォーム成果発表会, Jan 25, 2018
がんと代謝研究の最前線

近藤祥司

抗加齢医学会, Jun 2, 2017
老化に伴う多角的治療戦略

近藤祥司

第60回日本心身医学会近畿地方会, Mar 2, 2017
ストレス老化シグナルと解糖系代謝

近藤祥司

第68回日本細胞生物学会, Jun 16, 2016
老化の多様性を規定する代謝・液性因子

近藤祥司

第58回日本老年医学会, Jun 9, 2016

Research Projects

Study of aging metabolites for remodeling of super-aging society

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jul, 2020 - Mar, 2022

Kondoh Hiroshi
Innovative search of well-ageing related metabolites

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jun, 2018 - Mar, 2020

Kondoh Hiroshi
Investigation for the metabolic basis of ageing diversity

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Kondoh Hiroshi
Investigation for metabolic features in divergency of ageing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018

Kondoh Hirohsi
The analysis of conversion mechanism from ageing to tumorigenesis by the metabolic-remodeling of glycolysis.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2017

Mikawa Takumi, KONDOH Hiroshi
Investigation for metabolic features in divergency of ageing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Jul, 2014 - Mar, 2017

Kondoh Hirohsi
Metabolomic analysis for improvement of healthy lifespan

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Hiroshi Kondoh, Yanagida Mitsuhiro
Senescence-inducing stress modulates glycolysis and the Warburg effect

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2011 - Mar, 2014

KONDOH Hiroshi, YOKODE Masayuki, OKAMOTO Koji, SOGA Tomoyoshi, TAKAORI Akifumi, TANAKA Tomoaki
Role of protein homeostasis in cardiac aging

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2009 - 2011

SHIOI Tetsuo, KONDOH Hiroshi
A study for an essential metabolic shift in glycolytic pathway observed during the transition from cellular senescence to carcinogenesis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

KONDOH Hiroshi, YOKODE Masayuki, MARUYAMA Takeshi

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