2005年4月
Long-term clinical course of a patient with anti PL-12 antibody accompanied by interstitial pneumonia and severe pulmonary hypertension
INTERNAL MEDICINE
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- 巻
- 44
- 号
- 4
- 開始ページ
- 319
- 終了ページ
- 325
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2169/internalmedicine.44.319
- 出版者・発行元
- JAPAN SOC INTERNAL MEDICINE
We report a case of a patient with anti PL-12 antibody accompanied by interstitial pneumonia and severe pulmonary hypertension. At first presentation, hyperkeratotic skin lesions were found, although the diagnosis of CVD was not conclusive. Lung histology showed diffuse fibrosing interstitial pneumonia predominantly in the subpleural regions. During the seven-year follow-up period, severe pulmonary hypertension developed, although the progression of lung fibrosis was relatively limited. Anti-PL12 antibody was detected, and therefore the patient was diagnosed as having antisynthetase syndrome. Lung histology and pulmonary arteriogram suggested that vascular involvement of the disease contributed to the development of severe pulmonary hypertension.
- リンク情報
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- DOI
- https://doi.org/10.2169/internalmedicine.44.319
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902225244081340
- CiNii Articles
- http://ci.nii.ac.jp/naid/10015461889
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/15897644
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000229158700013&DestApp=WOS_CPL
- ID情報
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- DOI : 10.2169/internalmedicine.44.319
- ISSN : 0918-2918
- J-Global ID : 200902225244081340
- CiNii Articles ID : 10015461889
- PubMed ID : 15897644
- Web of Science ID : WOS:000229158700013