論文

査読有り
2018年2月16日

Iron-Catalyzed Aminative Cyclization/Intermolecular Homolytic Aromatic Substitution Using Oxime Esters and Simple Arenes

Chemistry - An Asian Journal
  • Takuya Shimbayashi
  • ,
  • Kazuhiro Okamoto
  • ,
  • Kouichi Ohe

13
4
開始ページ
395
終了ページ
399
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1002/asia.201701634
出版者・発行元
John Wiley and Sons Ltd

Intermolecular C−H alkylation of simple arenes in the presence of an iron catalyst has been achieved in a cascade manner with an aminative cyclization triggered by N−O bond cleavage of an alkene-tethered oxime ester. Various arenes, including electron-rich and electron-poor arenes, and heteroarenes can be employed in the reaction system. Regioselectivity and radical trapping experiments support the involvement of alkyl radical species, which undergo a homolytic aromatic substitution (HAS) to afford the arylation products.

リンク情報
DOI
https://doi.org/10.1002/asia.201701634

エクスポート
BibTeX RIS