Ryohsuke Kurihara - My portal

Profile Information

Affiliation: Assistant Professor, Faculty of Medicine School of Medicine, Kagawa University

Degree: 博士（工学）(九州大学)

J-GLOBAL ID: 201401006405004670
researchmap Member ID: 7000009696

Research Interests

Research Areas

Research History

Dec, 2018 - Present

School of Medicine, Faculty of Medicine, Kagawa University
Sep, 2015 - Nov, 2018

College of Science and Engineering College of Science and Engineering Department of Chemistry and Biological Science Assistant Professor
Apr, 2013 - Aug, 2015

Graduate School of Medicine Kyoto University Researcher
May, 2012 - Mar, 2013

Graduate School of Engineering Kyoto University Researcher

Education

Apr, 2004 - Mar, 2012

Kyushu University
Apr, 2000 - Mar, 2004

Faculty of Engineering, Chiba University

Papers

Solvent-free multi-alkylation of urea with alcohols catalyzed by titania-supported iridium catalyst with a strong metal-support interaction

Han Yu, Lin Ma, Kenji Wada, Ryohsuke Kurihara, Qi Feng, Shinobu Uemura, Kyosuke Isoda

Catalysis Today, 411-412 113839-113839, 2022 Peer-reviewed
Changes of C≡C Triple Bond Vibration that Disclosed Non-Canonical Cytosine Protonation in i-Motif-Forming Oligodeoxynucleotides

Ryota Itaya, Wakana Idei, Takashi Nakamura, Tatsuya Nishihara, Ryohsuke Kurihara, Akimitsu Okamoto, Kazuhito Tanabe

ACS Omega, 6(47) 31595-31604, 2021 Peer-reviewed
Rapid Multialkylation of Aqueous Ammonia with Alcohols by Heterogeneous Iridium Catalyst under Simple Conditions

Han Yu, Lin Ma, Kenji Wada, Ryohsuke Kurihara, Qi Feng, Shinobu Uemura, Kyosuke Isoda

ChemCatChem, 13(16) 3588-3593, 2021 Peer-reviewed
Development of Titania-supported Iridium Catalysts for the Acceptor-less Dehydrogenative Synthesis of Benzoxazoles

Han YU, Lin MA, Kenji WADA, Ryohsuke KURIHARA, Qi FENG, Shinobu UEMURA, Kyosuke ISODA

Journal of the Japan Petroleum Institute, 64(5) 271-279, 2021 Peer-reviewed
Modulation of cell membrane functionalization with aggregates of oligodeoxynucleotides containing alkyl chain-modified uridines

Reina Kainuma, Yuto Motohashi, Tatsuya Nishihara, Ryohsuke Kurihara, Kazuhito Tanabe

Organic & Biomolecular Chemistry, 18(28) 5406-5413, 2020 Peer-reviewed
Cellular uptake of aggregates consisting of oligodeoxynucleotides bearing alkyl chain at strand end

A. Kitao, R. Kurihara, K. Tanabe

Photomedicine and Photobiology, 41, 13-15, 2020 Peer-reviewed
Hybridizing Oligonucleotides with Hydrophobic Peptide Nucleic Acids Assists Their Cellular Uptake through Aggregate Formation

Sotaro Misu, Ryohsuke Kurihara, Reina Kainuma, Ryugai Sato, Tatsuya Nishihara, Kazuhito Tanabe

ChemBioChem, 21(8) 1140-1143, 2020 Peer-reviewed
Aggregate Formation of BODIPY-Tethered Oligonucleotides That Led to Efficient Intracellular Penetration and Gene Regulation

Wataru Asahi, Ryohsuke Kurihara, Kotaro Takeyama, Yui Umehara, Yu Kimura, Teruyuki Kondo, Kazuhito Tanabe

ACS Applied Bio Materials, 2(10) 4456-4463, 2019 Peer-reviewed
A novel interleukin‐13 receptor alpha 2‐targeted hybrid peptide for effective glioblastoma therapy

Ryohsuke Kurihara, Tomohisa Horibe, Eiko Shimizu, Aya Torisawa, Arong Gaowa, Masayuki Kohno, Koji Kawakami

Chemical Biology & Drug Design, 94(1) 1402-1413, 2019 Peer-reviewed
Enzymatic activation of indolequinone-substituted 5-fluorodeoxyuridine prodrugs in hypoxic cells

Yota Jiho, Ryohsuke Kurihara, Kiyohiko Kawai, Hisatsugu Yamada, Yoshihiro Uto, Kazuhito Tanabe

Bioorganic & Medicinal Chemistry Letters, 29(11) 1304-1307, 2019 Peer-reviewed
Tracking the Oxygen Status in the Cell Nucleus with a Hoechst-Tagged Phosphorescent Ruthenium Complex

Daiki Hara, Yui Umehara, Aoi Son, Wataru Asahi, Sotaro Misu, Ryohsuke Kurihara, Teruyuki Kondo, Kazuhito Tanabe

ChemBioChem, 19(9) 956-962, 2018 Peer-reviewed
Phosphorescent Ruthenium Complexes with Bromopyrene Unit that Enhance Oxygen Sensitivity

R. Kurihara, R. Ikegami, W. Asahi, K. Tanabe

Bioorg. Med. Chem., 26, 4595-4601, 2018 Peer-reviewed
Release of small molecules from aggregates consisting of an amphiphilic oligonucleotide functionalized by a photochromic azobenzene unit

T. Itagaki, R. Kurihara, K. Tanabe

Tetrahedron Lett., 59, 3112-3115, 2018 Peer-reviewed
Glutathione arrest in the pores of mesoporous silica nanoparticles bearing maleimide units to enhance the radiation effects

M. Ito, R. Kurihara, K. Tanabe

Photomed. Photobiol., 40, 11-15, 2018 Peer-reviewed
Aggregate Formation of Oligonucleotides that Assist Molecular Imaging for Tracking of the Oxygen Status in Tumor Tissue

Kazuki Yoshihara, Kohei Takagi, Aoi Son, Ryohsuke Kurihara, Kazuhito Tanabe

ChemBioChem, 18(16) 1650-1658, 2017 Peer-reviewed
Confined Singlet Oxygen in Mesoporous Silica Nanoparticles: Selective Photochemical Oxidation of Small Molecules in Living Cells

Takuma Nakamura, Aoi Son, Yui Umehara, Takeo Ito, Ryohsuke Kurihara, Yuta Ikemura, Kazuhito Tanabe

Bioconjugate Chemistry, 27(4) 1058-1066, Apr 20, 2016 Peer-reviewed
Monitoring Bip promoter activation during cancer cell growth by bioluminescence imaging at the single-cell level

Tomohisa Horibe, Aya Torisawa, Ryohsuke Kurihara, Ryutaro Akiyoshi, Yoko Hatta-Ohashi, Hirobumi Suzuki, Koji Kawakami

Integrative Cancer Science and Therapeutics, 2(6), 2016 Peer-reviewed
Preparation of alkyne-labeled 2-nitroimidazoles for identification of tumor hypoxia by Raman spectroscopy

Ryohsuke Kurihara, Yuta Ikemura, Kazuhito Tanabe

Bioorganic & Medicinal Chemistry Letters, 26(20) 4892-4894, 2016 Peer-reviewed
Controlling Localization and Excretion of Nanoparticles by Click Modification of the Surface Chemical Structures inside Living Cells

Takeo Ito, Takuma Nakamura, Eriko Kusaka, Ryohsuke Kurihara, Kazuhito Tanabe

ChemPlusChem, 80(5) 796-799, 2015 Peer-reviewed
Electron transport through 5-substituted pyrimidines in DNA: electron affinities of uracil and cytosine derivatives differently affect the apparent efficiencies

Takeo Ito, Ryohsuke Kurihara, Nihiro Utsumi, Yuta Hamaguchi, Kazuhito Tanabe, Sei-ichi Nishimoto

Chemical Communications, 49(87) 10281-10281, 2013 Peer-reviewed

Misc.

Preparation of Glycan Arrays Using Glycopeptides Derived From Biomaterials

Shin-ichi Nakakita, Yukari Nakakita, Ryohsuke Kurihara, Jun Hirabayashi

Methods in Molecular Biology, 45-58, 2022

Books and Other Publications

＜注目の論文＞微小ナノ粒子の新たな可能性

月刊「化学」, 化学同人, 72, 63-64, 2017
がん治療における標的超音波造影剤によるアポトーシスの誘導

翻訳, 栗原亮介, 監修, 川上浩司

Pharm Tech Japan, 31, 105-113, 2015
マクロファージに対する非凝縮DNA送達およびトランスフェクションシステムとしてのアルギン酸カルシウム微粒子

翻訳, 栗原亮介, 監修, 川上浩司

Pharm Tech Japan, 30, 65-72, 2014

Presentations

会合体形成特性を持つ両親媒性siRNAの機能評価

栗原亮介, 朝日航, 田邉一仁

日本化学会第98春季年会, Mar, 2018
会合体形成特性を持つ疎水性蛍光色素を備えた両親媒性核酸の開発

栗原亮介, 朝日航, 田邉一仁

国際癌治療増感研究協会第20回菅原・大西記念癌増感シンポジウム, Feb, 2018

Professional Memberships

Research Projects

核酸会合体によるセラノスティクスへの応用

科研費補助金（若手研究）, 日本学術振興会, 2019 - 2021

栗原亮介
Study on new strategy of glioblastoma treatment by molecular targeted anti-cancer hybrid peptide

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Kawakami Koji, HORIBE TOMOHISA, KOHNO MASAYUKI, KURIHARA RYOUSUKE, SETO KAHORI, ARONGGAOWA
ハイブリッドペプチドとデンドリマーを組合わせた難治性癌に対する新規抗癌剤の開発

科研費補助金（若手研究B）, 日本学術振興会, 2014 - 2016

栗原亮介

Industrial Property Rights

特開2012-001461 金ナノロッドを含有するS/O製剤

新留琢郎, 新留康郎, 神谷典穂, 後藤雅宏, 片山佳樹, ダークロン・ピスワン, 野瀬圭介, 栗原亮介

Social Activities

おもしろワクワク化学の世界 '21香川化学展―オンライン開催―

Logistic support

日本化学会中国四国支部, Aug 7, 2021 - Aug 8, 2021
おもしろワクワク化学の世界 '19香川化学展

Logistic support

日本化学会中国四国支部, Aug 3, 2019 - Aug 4, 2019
細胞のなかを見てみよう

Lecturer

相模原市町田市, さがまちカレッジ, Aug 1, 2017