2022年
Induction of Human Natural Killer Cells Under Defined Conditions by Seamless Transition from Maintenance Culture of Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
- ,
- 巻
- 2463
- 号
- 開始ページ
- 47
- 終了ページ
- 52
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1007/978-1-0716-2160-8_4
The use of pluripotent stem cells (PSCs) as a source of natural killer cells (NK cells) can improve reproducibility in the analysis of the pathogenesis of NK cell-associated diseases and in the production of off-the-shelf cellular medicines. We have developed a method for the differentiation of NK cells from human PSCs under serum-free and two-dimensional condition. Our method enables the seamless transition from maintenance of PSCs to differentiation of NK cells, without the use of any techniques other than medium exchange and whole culture passage.
- リンク情報
- ID情報
-
- DOI : 10.1007/978-1-0716-2160-8_4
- PubMed ID : 35344166