2013年
Lack of goal attainment regarding the low-density lipoprotein cholesterol level in the management of type 2 diabetes mellitus.
Internal medicine (Tokyo, Japan)
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- 巻
- 52
- 号
- 21
- 開始ページ
- 2409
- 終了ページ
- 15
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.2169/internalmedicine.52.0599
- 出版者・発行元
- JAPAN SOC INTERNAL MEDICINE
OBJECTIVE: The management of diabetes mellitus includes controlling the blood glucose level, body weight, blood pressure and serum lipid level. The coexistence of diabetes and a high low-density lipoprotein cholesterol (LDL-C) level promotes atherosclerosis of the coronary arteries and increases the risk of coronary artery disease (CAD). We compared the rates of attainment of LDL-C goals in type 2 diabetes patients receiving primary and secondary prevention therapy, the former without a history of CAD and the latter with a history of CAD. Because patients receiving secondary prevention are at greater risk of coronary events, LDL-C management is especially important in this group. This study was designed to determine how frequently diabetic patients attain their LDL-C goals and identify the reasons for the lack of attainment. METHODS: The groups were distinguished according to the patients' medical records. Contributory factors for the patients not achieving their goals were recorded in a questionnaire filled out by each patient's physician. RESULTS: The overall attainment rate in both groups was 61%. The most frequent impediment in both groups was "an LDL-C level above or below the goal at every hospital visit" followed by "continuously sufficient effects of dietary therapy only" and the "management of LDL-C by other departments or hospitals," the latter reflecting the increasing problems of polydisease and polypharmacy in diabetes care. CONCLUSION: Polydisease and polypharmacy issues in diabetes patients with a history of CAD constitute a growing barrier to medication adherence and the attainment of treatment goals.
- リンク情報
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- DOI
- https://doi.org/10.2169/internalmedicine.52.0599
- CiNii Articles
- http://ci.nii.ac.jp/naid/130003383678
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/24190144
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000327938400003&DestApp=WOS_CPL
- ID情報
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- DOI : 10.2169/internalmedicine.52.0599
- ISSN : 0918-2918
- eISSN : 1349-7235
- CiNii Articles ID : 130003383678
- PubMed ID : 24190144
- Web of Science ID : WOS:000327938400003