BROWNIII Ellsworth John (John Brown) - マイポータル

基本情報

所属: 京都大学

J-GLOBAL ID: 201401082094378537
researchmap会員ID: 7000009012

論文

Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain.

Akihide Takeuchi, Kei Iida, Toshiaki Tsubota, Motoyasu Hosokawa, Masatsugu Denawa, J B Brown, Kensuke Ninomiya, Mikako Ito, Hiroshi Kimura, Takaya Abe …

Cell reports 23(5) 1326-1341 2018年5月1日査読有り
Advancing drug discovery via GPU-based deep learning

Erik Gawehn, Jan Hiss, J.B. Brown, Gisbert Schneider

Expert Opinion in Drug Discovery, in press 2018年4月査読有り
Chemogenomic Active Learning's Domain of Applicability on Small, Sparse qHTS Matrices: A Study Using Cytochrome P450 and Nuclear Hormone Receptor Families

Christin Rakers, Rifat Ara Najnin, Ahsan Habib Polash, Shunichi Takeda, J. B. Brown

ChemMedChem 13(6) 511-521 2018年3月20日査読有り
Adaptive mining and model building of medicinal chemistry data with a multi-metric perspective

BROWNIII,John Ellsworth

Future Medicinal Chemistry, in press 2018年査読有り
Classifiers and their Metrics Quantified

J. B. Brown

Molecular Informatics 37(1) 1700127 2018年1月1日査読有り
Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks

Ryusuke Murakami, Noriomi Matsumura, J. B. Brown, Koichiro Higasa, Takanobu Tsutsumi, Mayumi Kamada, Hisham Abou-Taleb, Yuko Hosoe, Sachiko Kitamura, Ken Yamaguchi …

AMERICAN JOURNAL OF PATHOLOGY 187(10) 2246-2258 2017年10月査読有り
Active learning for computational chemogenomics

Daniel Reker, Petra Schneider, Gisbert Schneider, J. B. Brown

FUTURE MEDICINAL CHEMISTRY 9(4) 381-402 2017年3月査読有り
Small Random Forest Models for Effective Chemogenomic Active Learning

Christin Rakers, Daniel Reker, J.B. Brown

Journal of Computer Aided Chemistry 18 124-142 2017年査読有り
Prediction of taxane and platinum sensitivity in ovarian cancer based on gene expression profiles

Ryusuke Murakami, Noriomi Matsumura, J.B. Brown, Zhipeng Wang, Ken Yamaguchi, Kaoru Abiko, Yumiko Yoshioka, Junzo Hamanishi, Tsukasa Baba, Masafumi Koshiyama …

Gyncecologic Oncology 141-149 2016年2月査読有り
Association between UGT1A1*28*28 genotype and lung cancer in the Japanese population

Yoshitaka Nishikawa, Masashi Kanai, Maiko Narahara, Akiko Tamon, J.B. Brown, Kei Taneishi, Masahiko Nakatsui, Kazuya Okamoto, Yu Uneno, Daisuke Yamaguchi …

International Journal of Clinical Oncology 1-5 2016年査読有り
Reliable pre-eclampsia pathways based on multiple independent microarray data sets

Kaoru Kawasaki, Eiji Kondoh, Yoshitsugu Chigusa, Mari Ujita, Ryusuke Murakami, Haruta Mogami, J. B. Brown, Yasushi Okuno, Ikuo Konishi

MOLECULAR HUMAN REPRODUCTION 21(2) 217-224 2015年2月査読有り
Antipsychotics-Associated Serious Adverse Events in Children: An Analysis of the FAERS Database

Goji Kimura, Kaori Kadoyama, J. B. Brown, Tsutomu Nakamura, Ikuya Miki, Kohshi Nisiguchi, Toshiyuki Sakaeda, Yasushi Okuno

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 12(2) 135-140 2015年査読有り
Constructing a Foundational Platform Driven by Japan's K Supercomputer for Next-Generation Drug Design

J. B. Brown, Masahiko Nakatsui, Yasushi Okuno

MOLECULAR INFORMATICS 33(11-12) 732-741 2014年12月査読有り
Computational chemogenomics: Is it more than inductive transfer?

J. B. Brown, Yasushi Okuno, Gilles Marcou, Alexandre Varnek, Dragos Horvath

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN 28(6) 597-618 2014年6月査読有り
An Evolutionary Optimizer of libsvm Models

Dragos Horvath, J.B. Brown, Gilles Marcou, Alexandre Varnek

Challenges 5 450 2014年査読有り
Compound-protein interaction prediction within chemogenomics: Theoretical concepts, practical usage, and future directions

J. B. Brown, Satoshi Niijima, Yasushi Okuno

Molecular Informatics 32(11-12) 906-921 2013年12月査読有り
Chemical Genomics Approach for GPCR-Ligand Interaction Prediction and Extraction of Ligand Binding Determinants

Akira Shiraishi, Satoshi Niijima, J. B. Brown, Masahiko Nakatsui, Yasushi Okuno

JOURNAL OF CHEMICAL INFORMATION AND MODELING 53(6) 1253-1262 2013年6月査読有り
Chemical Genomics Approach for GPCR-Ligand Interaction Prediction and Extraction of Ligand Binding Determinants

Akira Shiraishi, Satoshi Niijima, J. B. Brown, Masahiko Nakatsui, Yasushi Okuno

JOURNAL OF CHEMICAL INFORMATION AND MODELING 53(6) 1253-1262 2013年6月査読有り
Staying Grounded in Reality - an Opinion on Why Informatics Students Should Have Laboratory Experience

J. B. Brown

MOLECULAR INFORMATICS 31(11-12) 777-781 2012年12月査読有り
Systems Biology and Systems Chemistry: New Directions for Drug Discovery

J. B. Brown, Yasushi Okuno

CHEMISTRY & BIOLOGY 19(1) 23-28 2012年1月査読有り

もっとみる

MISC

Chemogenomic approach to comprehensive predictions of ligand-target interactions: A comparative study

J.B. Brown, S. Niijima, A. Shiraishi, M. Nakatsui, Y. Okuno

Proceedings - 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2012 136-142 2012年査読有り
Multiple methods for protein side chain packing using maximum weight cliques.

J.B. Brown, K.C. Dukka Bahadur, E. Tomita, T. Akutsu

Genome informatics. International Conference on Genome Informatics 17(1) 3-12 2006年査読有り
Large scale protein side-chain packing based on maximum edge-weight clique finding algorithm

D Bahadur, J.B. Brown, E Tomita, J Suzuki, T Akutsu

2005 International Joint Conference of InCoB, AASBi and KSBI (BIOINFO2005) 228-233 2005年査読有り
Large scale validation of a computer aided polyp detection algorithm for CT colonography using cluster computing

Bitter, I, JE Brown, D Brickman, RM Summers

MEDICAL IMAGING 2004: PHYSIOLOGY, FUNCTION, AND STRUCTURE FROM MEDICAL IMAGES 5(23) 290-294 2004年査読有り

書籍等出版物

Unifying bioinformatics and chemoinformatics for drug design

BROWNIII,John Ellsworth

Hewlett-Packard Japan 2013年