新堂啓祐 (Keisuke Shindou) - マイポータル

Core binding factor β protects HIV, type 1 accessory protein viral infectivity factor from MDM2-mediated degradation

Matsui Y, Shindo K, Nagata K, Yoshinaga N, Shirakawa K, Kobayashi M, Takaori-Kondo A

Journal of Biological Chemistry 291(48) 24892-24899 2016年11月査読有り

Classical NF-κB pathway is responsible for APOBEC3B expression in cancer cells

Maruyama W, Shirakawa K, Matsui H, Matsumoto T, Yamazaki H, Sarca A.D, Kazuma Y, Kobayashi M, Shindo K, Takaori-Kondo A

Biochemical and Biophysical Research Communications 478(3) 1466-1471 2016年9月査読有り

ASK1 restores the antiviral activity of APOBEC3G by disrupting HIV-1 Vif-mediated counteraction

Kei Miyakawa, Satoko Matsunaga, Kazuhiko Kanou, Atsushi Matsuzawa, Ryo Morishita, Ayumi Kudoh, Keisuke Shindo, Masaru Yokoyama, Hironori Sato, Hirokazu Kimura …

NATURE COMMUNICATIONS 6(6945) 1-10 2015年4月査読有り

Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia

Tada K, Kobayashi M, Takiuchi Y, Iwai F, Sakamoto T, Nagata K, Shinohara M, Io K, Shirakawa K, Hishizawa M …

1(e1400203) 1-13 2015年4月査読有り

Small molecules that inhibit Vif-induced degradation of APOBEC3G

Masashi Matsui, Keisuke Shindo, Taisuke Izumi, Katsuhiro Io, Masanobu Shinohara, Jun Komano, Masayuki Kobayashi, Norimitsu Kadowaki, Reuben S. Harris, Akifumi Takaori-Kondo

VIROLOGY JOURNAL 11(1) 2014年7月査読有り

Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis

Matsui Y, Shindo K, Nagata K, Io K, Tada K, Iwai F, Kobayashi M, Kadowaki N, Harris R.S, Takaori-Kondo A

Virology 449 82-87 2014年1月査読有り

CKIP-1 Is an Intrinsic Negative Regulator of T-Cell Activation through an Interaction with CARMA1

Takashi Sakamoto, Masayuki Kobayashi, Kohei Tada, Masanobu Shinohara, Katsuhiro Io, Kayoko Nagata, Fumie Iwai, Yoko Takiuchi, Yasuyuki Arai, Kouhei Yamashita …

PLOS ONE 9(1) 2014年1月査読有り

HIV-1 Vif: a guardian of the virus that opens up a new era in the research field of restriction factors

Akifumi Takaori-Kondo, Keisuke Shindo

FRONTIERS IN MICROBIOLOGY 4(FEB) 2013年2月査読有り

APOBEC3B can impair genomic stability by inducing base substitutions in genomic DNA in human cells

Masanobu Shinohara, Katsuhiro Io, Keisuke Shindo, Masashi Matsui, Takashi Sakamoto, Kohei Tada, Masayuki Kobayashi, Norimitsu Kadowaki, Akifumi Takaori-Kondo

SCIENTIFIC REPORTS 2 2012年11月査読有り

A comparison of two single-stranded DNA binding models by mutational analysis of APOBEC3G

Keisuke Shindo, Ming Li, Phillip J. Gross, William L. Brown, Elena Harjes, Yongjian Lu, Hiroshi Matsuo, Reuben S. Harris

Biology 1(2) 260-276 2012年8月2日査読有り

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

J{\"a}ger S, Kim D.Y, Hultquist J.F, Shindo K, Larue R.S, Kwon E, Li M, Anderson B.D, Yen L, Stanley D …

Nature 481(7381) 371-375 2012年1月査読有り

A Single Amino Acid in Human APOBEC3F Alters Susceptibility to HIV-1 Vif

John S. Albin, Rebecca S. LaRue, Jessalyn A. Weaver, William L. Brown, Keisuke Shindo, Elena Harjes, Hiroshi Matsuo, Reuben S. Harris

JOURNAL OF BIOLOGICAL CHEMISTRY 285(52) 40785-40792 2010年12月査読有り

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

Eric W. Refsland, Mark D. Stenglein, Keisuke Shindo, John S. Albin, William L. Brown, Reuben S. Harris

NUCLEIC ACIDS RESEARCH 38(13) 4274-4284 2010年7月査読有り

Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces

Shivender M. D. Shandilya, Madhavi N. L. Nalam, Ellen A. Nalivaika, Phillip J. Gross, Johnathan C. Valesano, Keisuke Shindo, Ming Li, Mary Munson, William E. Royer, Elena Harjes …

STRUCTURE 18(1) 28-38 2010年1月査読有り

An Extended Structure of the APOBEC3G Catalytic Domain Suggests a Unique Holoenzyme Model

Elena Harjes, Phillip J. Gross, Kuan-Ming Chen, Yongjian Lu, Keisuke Shindo, Roni Nowarski, John D. Gross, Moshe Kotler, Reuben S. Harris, Hiroshi Matsuo

JOURNAL OF MOLECULAR BIOLOGY 389(5) 819-832 2009年6月査読有り

Evolution of HIV-1 isolates that use a novel Vif-independent mechanism to resist restriction by human APOBEC3G

Guylaine Hache, Keisuke Shindo, John S. Albin, Reuben S. Harris

CURRENT BIOLOGY 18(11) 819-824 2008年6月査読有り

Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G

Kuan-Ming Chen, Elena Harjes, Phillip J. Gross, Amr Fahmy, Yongjian Lu, Keisuke Shindo, Reuben S. Harris, Hiroshi Matsuo

NATURE 452(7183) 116-U16 2008年3月査読有り

Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G

Kuan-Ming Chen, Natalia Martemyanova, Yongjian Lu, Keisuke Shindo, Hiroshi Matsuo, Reuben S. Harris

FEBS LETTERS 581(24) 4761-4766 2007年10月査読有り

APOBEC3G targets specific virus species

M Kobayashi, A Takaori-Kondo, K Shindo, A Abudu, K Fukunaga, T Uchiyama