論文

査読有り
2013年

Amphiphilic nanogel of enzymatically synthesized glycogen as an artificial molecular chaperone for effective protein refolding

RSC ADVANCES
  • Shigeo Takeda
  • ,
  • Haruko Takahashi
  • ,
  • Shin-ichi Sawada
  • ,
  • Yoshihiro Sasaki
  • ,
  • Kazunari Akiyoshi

3
48
開始ページ
25716
終了ページ
25718
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1039/c3ra44572k
出版者・発行元
ROYAL SOC CHEMISTRY

Enzymatically synthesized glycogen (ESG) bearing hydrophobic groups were prepared to construct a new artificial molecular chaperone system. The radius of the amphiphilic ESG nanogel was approximately 15 nm. The nanogels prevented irreversible aggregation of carbonic anhydrase. Cyclodextrin induced the release of carbonic anhydrase in its active form via a one-step mechanism without dissociation of the nanogels.

リンク情報
DOI
https://doi.org/10.1039/c3ra44572k
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000327261700034&DestApp=WOS_CPL
ID情報
  • DOI : 10.1039/c3ra44572k
  • ISSN : 2046-2069
  • SCOPUS ID : 84887893695
  • Web of Science ID : WOS:000327261700034

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