2013年
Amphiphilic nanogel of enzymatically synthesized glycogen as an artificial molecular chaperone for effective protein refolding
RSC ADVANCES
- ,
- ,
- ,
- ,
- 巻
- 3
- 号
- 48
- 開始ページ
- 25716
- 終了ページ
- 25718
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/c3ra44572k
- 出版者・発行元
- ROYAL SOC CHEMISTRY
Enzymatically synthesized glycogen (ESG) bearing hydrophobic groups were prepared to construct a new artificial molecular chaperone system. The radius of the amphiphilic ESG nanogel was approximately 15 nm. The nanogels prevented irreversible aggregation of carbonic anhydrase. Cyclodextrin induced the release of carbonic anhydrase in its active form via a one-step mechanism without dissociation of the nanogels.
- リンク情報
- ID情報
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- DOI : 10.1039/c3ra44572k
- ISSN : 2046-2069
- SCOPUS ID : 84887893695
- Web of Science ID : WOS:000327261700034