河野雅之 (Masayuki Kono) - マイポータル

基本情報

所属: 京都大学

J-GLOBAL ID: 201401049906022939
researchmap会員ID: 7000009239

論文

Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma

Osamu Kikuchi, Shinya Ohashi, Tomohisa Horibe, Masayuki Kohno, Yukie Nakai, Shin'ichi Miyamoto, Tsutomu Chiba, Manabu Muto, Koji Kawakami

SCIENTIFIC REPORTS 6 22452 2016年3月査読有り
Potent anti-tumor effects of EGFR-targeted hybrid peptide on mice bearing liver metastases

Arong Gaowa, Tomohisa Horibe, Masayuki Kohno, Hiroshi Harada, Masahiro Hiraoka, Koji Kawakami

CLINICAL & EXPERIMENTAL METASTASIS 33(1) 87-95 2016年1月査読有り
Enhancement of anti-tumor activity of hybrid peptide in conjugation with carboxymethyl dextran via disulfide linkers

Arong Gaowa, Tomohisa Horibe, Masayuki Kohno, Yasuhiko Tabata, Hiroshi Harada, Masahiro Hiraoka, Koji Kawakami

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 92 228-236 2015年5月査読有り
The Membrane-Lytic Peptides K8L9 and Melittin Enter Cancer Cells via Receptor Endocytosis following Subcytotoxic Exposure

Masayuki Kohno, Tomohisa Horibe, Koji Ohara, Shinji Ito, Koji Kawakami

CHEMISTRY & BIOLOGY 21(11) 1522-1532 2014年11月査読有り
Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide

Tomohisa Horibe, Aya Torisawa, Masayuki Kohno, Koji Kawakami

BMC CANCER 14 615 2014年8月査読有り
Combination of hybrid peptide with biodegradable gelatin hydrogel for controlled release and enhancement of anti-tumor activity in vivo

Arong Gaowa, Tomohisa Horibe, Masayuki Kohno, Keisuke Sato, Hiroshi Harada, Masahiro Hiraoka, Yasuhiko Tabata, Koji Kawakami

JOURNAL OF CONTROLLED RELEASE 176(1) 1-7 2014年2月査読有り
Targeting interleukin-4 receptor alpha by hybrid Peptide for novel biliary tract cancer therapy.

(584650) 2014年査読有り
Entry of a cationic lytic-type peptide into the cytoplasm via endocytosis-dependent and -independent pathways in human glioma U251 cells

Koji Ohara, Masayuki Kohno, Tsutomu Hamada, Koji Kawakami

PEPTIDES 50 28-35 2013年12月査読有り
Localization of the anti-cancer peptide EGFR-lytic hybrid peptide in human pancreatic cancer BxPC-3 cells by immunocytochemistry

Koji Ohara, Masayuki Kohno, Koji Kawakami

JOURNAL OF PEPTIDE SCIENCE 19(8) 511-515 2013年8月査読有り
Interleukin-4 receptor α-based hybrid peptide effectively induces antitumor activity in head and neck squamous cell carcinoma.

. 29(6) 2147-2153 2013年6月査読有り
HER2-Targeted Hybrid Peptide That Blocks HER2 Tyrosine Kinase Disintegrates Cancer Cell Membrane and Inhibits Tumor Growth In Vivo

Megumi Kawamoto, Tomohisa Horibe, Masayuki Kohno, Koji Kawakami

MOLECULAR CANCER THERAPEUTICS 12(4) 384-393 2013年4月査読有り
Immunogenicity and toxicity of transferrin receptor-targeted hybrid peptide as a potent anticancer agent

Megumi Kawamoto, Masayuki Kohno, Tomohisa Horibe, Koji Kawakami

CANCER CHEMOTHERAPY AND PHARMACOLOGY 71(3) 799-807 2013年3月査読有り
Inhibition of Neurite Outgrowth by a Neuropilin-1 Binding Peptide Derived from Semaphorin 3A

M. Kohno, K. Ohara, T. Horibe, K. Kawakami

International Journal of Peptide Research and Therapeutics 1-8 2013年査読有り
Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells

Tomohisa Horibe, Aya Torisawa, Masayuki Kohno, Koji Kawakami

MOLECULAR CANCER 11 2012年8月査読有り
Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells

Tomohisa Horibe, Aya Torisawa, Masayuki Kohno, Koji Kawakami

MOLECULAR CANCER 11 59 2012年8月査読有り
Cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90

Tomohisa Horibe, Megumi Kawamoto, Masayuki Kohno, Koji Kawakami

JOURNAL OF BIOSCIENCE AND BIOENGINEERING 114(1) 96-103 2012年7月査読有り
Targeting Interleukin-4 Receptor alpha with Hybrid Peptide for Effective Cancer Therapy

Liying Yang, Tomohisa Horibe, Masayuki Kohno, Mari Haramoto, Koji Ohara, Raj K. Puri, Koji Kawakami

MOLECULAR CANCER THERAPEUTICS 11(1) 235-243 2012年1月査読有り
Semaphorin 3A lytic hybrid peptide binding to neuropilin-1 as a novel anti-cancer agent in pancreatic cancer

Hanae Ueyama, Tomohisa Horibe, Oumi Nakajima, Koji Ohara, Masayuki Kohno, Koji Kawakami

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 414(1) 60-66 2011年10月査読有り
A novel transferrin receptor-targeted hybrid peptide disintegrates cancer cell membrane to induce rapid killing of cancer cells

Megumi Kawamoto, Tomohisa Horibe, Masayuki Kohno, Koji Kawakami

BMC CANCER 11 2011年8月査読有り
Characterization of antilytic peptide antibody: application for the detection of lytic-based hybrid peptide in serum samples

Koji Ohara, Tomohisa Horibe, Masayuki Kohno, Koji Kawakami

JOURNAL OF PEPTIDE SCIENCE 17(7) 493-498 2011年7月査読有り

もっとみる

産業財産権

特願特願2008-309176国際特許PTC出願中「EGFRを標的にした新規抗癌キメラペプチド」

川上浩司, 河野雅之, 堀部智久, 中島央美, 楊麗英, 原本真里
特願特願2008-292849国際特許PTC出願中「Hsp90を標的にした新規抗癌キメラペプチド」

川上浩司, 河野雅之, 堀部智久