2018年1月
Association between post-dialysis hemoglobin level and the survival of vascular access
Journal of Vascular Access
- 巻
- 19
- 号
- 1
- 開始ページ
- 69
- 終了ページ
- 75
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.5301/jva.5000798
- 出版者・発行元
- SAGE PUBLICATIONS LTD
Introduction: Although a few dialysis facilities conduct a complete blood cell count for some patients at post-dialysis, including hemoglobin, clinical findings supporting the interpretation of results are scarce. The aim of this study was to investigate the association between post-dialysis hemoglobin level and vascular access failure with clinical data.Methods: Study design: Case crossover design. Setting: Japanese dialysis facilities, which routinely take post-dialysis blood samples, including complete blood cell counts at least once a month. Participants: Hemodialysis patients who experienced vascular access failure in January 2010 until December 2014. Exposure: Post-dialysis hemoglobin level. Main outcome: Vascular access failure treated with endovascular treatment or operation. Statistical analysis: Self-matched odds ratios and 95% confidence intervals were estimated by comparing post-dialysis hemoglobin just before events ("case") with levels at 6 and 12 months before events ("control") using conditional logistic regression, and presented with restricted cubic spline.Results: Two hundred and thirty hemodialysis patients with vascular access failure were identified. Mean post-dialysis hemoglobin level before the failure was 11.8 g/dL (standard deviation 1.7). The spline curve showed that higher post-dialysis hemoglobin levels above 11.8 g/dL had a greater odds ratio for vascular access failure. Post-dialysis hemoglobin levels and odds ratios (95% confidence interval) for vascular access failure relative to the reference value (Hb 11.8 g/dL) were Hb 12.0 g/dL, 1.1 (1.0-1.1); Hb 14.0 g/dL, 1.4 (1.0-2.0); and Hb 16.0 g/dL, 2.1 (1.1-4.3).Conclusions: A higher post-dialysis hemoglobin level was associated with vascular access failure. Higher post-dialysis Hb could be a factor that triggers vascular access failure.
- リンク情報
-
- DOI
- https://doi.org/10.5301/jva.5000798
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/29076517
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000428729800011&DestApp=WOS_CPL
- Scopus
- https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85053467998&origin=inward
- Scopus Citedby
- https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85053467998&origin=inward
- ID情報
-
- DOI : 10.5301/jva.5000798
- ISSN : 1129-7298
- eISSN : 1724-6032
- PubMed ID : 29076517
- SCOPUS ID : 85053467998
- Web of Science ID : WOS:000428729800011