大澤光次郎 (Mitsujiro Osawa) - マイポータル

Bi-allelic loss of function variants of TBX6 causes a spectrum of malformation of spine and rib including congenital scoliosis and spondylocostal dysostosis.

Nao Otomo, Kazuki Takeda, Shunsuke Kawai, Ikuyo Kou, Long Guo, Mitsujiro Osawa, Cantas Alev, Noriaki Kawakami, Noriko Miyake, Naomichi Matsumoto …

Journal of medical genetics 56(9) 622-628 2019年9月査読有り

Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I.

Suga M, Kondo T, Imamura K, Shibukawa R, Okanishi Y, Sagara Y, Tsukita K, Enami T, Furujo M, Saijo K …

Stem cell research 36 101406-101406 2019年4月査読有り

Rescue of recurrent deep intronic mutation underlying cell type-dependent quantitative NEMO deficiency.

Bertrand Boisson, Yoshitaka Honda, Masahiko Ajiro, Jacinta Bustamante, Matthieu Bendavid, Andrew R Gennery, Yuri Kawasaki, Jose Ichishima, Mitsujiro Osawa, Hiroshi Nihira …

The Journal of clinical investigation 129(2) 583-597 2019年2月1日査読有り

Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development.

Karagiannis P, Takahashi K, Saito M, Yoshida Y, Okita K, Watanabe A, Inoue H, Yamashita JK, Todani M, Nakagawa M …

Physiological reviews 99(1) 79-114 2019年1月査読有り

Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors.

Koichi Oshima, Norikazu Saiki, Michihiro Tanaka, Hiromi Imamura, Akira Niwa, Ayako Tanimura, Ayako Nagahashi, Akiyoshi Hirayama, Keisuke Okita, Akitsu Hotta …

Biochemical and biophysical research communications 497(2) 719-725 2018年3月4日査読有り

Pluripotent stem cell models of Blau syndrome reveal an IFN-γ-dependent inflammatory response in macrophages.

Takada S, Kambe N, Kawasaki Y, Niwa A, Honda-Ozaki F, Kobayashi K, Osawa M, Nagahashi A, Semi K, Hotta A …

The Journal of allergy and clinical immunology 141(1) 339-349 2018年1月査読有り

Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation

Valentina Sanghez, Anna Luzzi, Don Clarke, Dustin Kee, Steven Beuder, Danielle Rux, Mitsujiro Osawa, Joaquin Madrenas, Tsui-Fen Chou, Michael Kyba …

PLOS ONE 12(10) e0186818 2017年10月査読有り

Identification of a High-Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell-Based Phenotype Dissection

Yuri Kawasaki, Hirotsugu Oda, Jun Ito, Akira Niwa, Takayuki Tanaka, Atsushi Hijikata, Ryosuke Seki, Ayako Nagahashi, Mitsujiro Osawa, Isao Asaka …

ARTHRITIS & RHEUMATOLOGY 69(2) 447-459 2017年2月査読有り

Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice (vol 89, pg 132, 2013)

Changshan Wang, Shunsuke Nakamura, Motohiko Oshima, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Mitsujiro Osawa, Yoichiro Kusunoki, Seishi Kyoizumi, Kazue Imai, Kei Nakachi …

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 91(8) 687-687 2015年8月査読有り

Sox17 as a candidate regulator of myeloid restricted differentiation potential

Maha Anani, Ikuo Nobuhisa, Mitsujiro Osawa, Atsushi Iwama, Kaho Harada, Kiyoka Saito, Tetsuya Taga

DEVELOPMENT GROWTH & DIFFERENTIATION 56(6) 469-479 2014年8月査読有り

Sox17-Mediated Maintenance of Fetal Intra-Aortic Hematopoietic Cell Clusters

Ikuo Nobuhisa, Mitsujiro Osawa, Mami Uemura, Yoko Kishikawa, Maha Anani, Kaho Harada, Haruna Takagi, Kiyoka Saito, Masami Kanai-Azuma, Yoshiakira Kanai …

MOLECULAR AND CELLULAR BIOLOGY 34(11) 1976-1990 2014年6月査読有り

Manipulation of Hematopoietic Stem Cells for Regenerative Medicine

Yaeko Nakajima-Takagi, Mitsujiro Osawa, Atsushi Iwama

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY 297(1) 111-120 2014年1月査読有り

Compromised hematopoiesis and increased DNA damage following non-lethal ionizing radiation of a human hematopoietic system reconstituted in immunodeficient mice

Changshan Wang, Shunsuke Nakamura, Motohiko Oshima, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Mitsujiro Osawa, Yoichiro Kusunoki, Seishi Kyoizumi, Kazue Imai, Kei Nakachi …

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 89(2) 132-137 2013年2月査読有り

Role of SOX17 in hematopoietic development from human embryonic stem cells

Yaeko Nakajima-Takagi, Mitsujiro Osawa, Motohiko Oshima, Haruna Takagi, Satoru Miyagi, Mitsuhiro Endoh, Takaho A. Endo, Naoya Takayama, Koji Eto, Tetsuro Toyoda …

Blood 121(3) 447-458 2013年1月17日査読有り

New approaches to expand hematopoietic stem and progenitor cells

Taito Nishino, Mitsujiro Osawa, Atsushi Iwama

EXPERT OPINION ON BIOLOGICAL THERAPY 12(6) 743-756 2012年6月査読有り

Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells

Shunsuke Nakamura, Motohiko Oshima, Jin Yuan, Atsunori Saraya, Satoru Miyagi, Takaaki Konuma, Satoshi Yamazaki, Mitsujiro Osawa, Hiromitsu Nakauchi, Haruhiko Koseki …

PLOS ONE 7(5) e36209 2012年5月査読有り

Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase

Taito Nishino, Changshan Wang, Makiko Mochizuki-Kashio, Mitsujiro Osawa, Hiromitsu Nakauchi, Atsushi Iwama

PLOS ONE 6(9) e24298 2011年9月査読有り

Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells

Motohiko Oshima, Mitsuhiro Endoh, Takaho A. Endo, Tetsuro Toyoda, Yaeko Nakajima-Takagi, Fumihiro Sugiyama, Haruhiko Koseki, Michael Kyba, Atsushi Iwama, Mitsujiro Osawa

BLOOD 117(15) E142-E150 2011年4月査読有り

A JAK2 Interdomain Linker Relays Epo Receptor Engagement Signals to Kinase Activation

Lequn Zhao, Hongyun Dong, Cheng Cheng Zhang, Lisa Kinch, Mitsujiro Osawa, Michelina Iacovino, Nikolai V. Grishin, Michael Kyba, Lily Jun-shen Huang

JOURNAL OF BIOLOGICAL CHEMISTRY 284(39) 26988-26998 2009年9月査読有り

Transcriptional profiling of hematopoietic stem cells by high-throughput sequencing

Yoshimi Yashiro, Hideo Bannai, Takashi Minowa, Tomohide Yabiku, Satoru Miyano, Mitsujiro Osawa, Atsushi Iwama, Hiromitsu Nakauchi

INTERNATIONAL JOURNAL OF HEMATOLOGY 89(1) 24-33 2009年1月査読有り

大澤光次郎

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