Takushi Takata

Profile Information

Affiliation: Kyoto University

J-GLOBAL ID: 201401033084994182
researchmap Member ID: 7000009604

Research Areas

Life sciences / Radiology /

Papers

Neutron flux evaluation algorithm with a combination of Monte Carlo and removal‐diffusion calculation methods for boron neutron capture therapy

Mai Nojiri, Takushi Takata, Naonori Hu, Yoshinori Sakurai, Minoru Suzuki, Hiroki Tanaka

Medical Physics, Jan 11, 2024
HER-2-targeted Boron Neutron Capture Therapy with Carborane-integrated Immunoliposomes Prepared via an Exchanging Reaction.

Riku Kawasaki, Ayano Oshige, Keita Yamana, Hidetoshi Hirano, Kotaro Nishimura, Yamato Miura, Ryuji Yorioka, Yu Sanada, Kaori Bando, Anri Tabata …

Chemistry (Weinheim an der Bergstrasse, Germany), e202302486, Oct 4, 2023
悪性神経膠腫に対する葉酸受容体標的ホウ素キャリアを用いたホウ素中性子捕捉療法

辻野晃平, 川端信司, 柏木秀基, 香山諒, 藤川喜貴, 福尾祐介, 平松亮, 宮武伸一, 呼尚徳, 高田卓志 …

日本癌治療学会学術集会抄録集, 61回 O23-4, Oct, 2023
Development of a prompt gamma-ray detector with an 8 × 8 array LaBr 3(Ce) scintillator and a multi-pixel photon counter for boron neutron capture therapy

Keita Okazaki, Hiroki Tanaka, Takushi Takata, Shinji Kawabata, Naonori Hu, Nishiki Matsubayashi, Tetsuya Mukawa, Yoshinori Sakurai, Minoru Suzuki

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1055 168546-168546, Oct, 2023
Proposal of recommended experimental protocols for in vitro and in vivo evaluation methods of boron agents for neutron capture therapy.

Yoshihide Hattori, Tooru Andoh, Shinji Kawabata, Naonori Hu, Hiroyuki Michiue, Hiroyuki Nakamura, Takahiro Nomoto, Minoru Suzuki, Takushi Takata, Hiroki Tanaka …

Journal of radiation research, Sep 16, 2023
Evaluation of the Effectiveness of Boron Neutron Capture Therapy with Iodophenyl-Conjugated closo-Dodecaborate on a Rat Brain Tumor Model.

Yoshiki Fujikawa, Yusuke Fukuo, Kai Nishimura, Kohei Tsujino, Hideki Kashiwagi, Ryo Hiramatsu, Naosuke Nonoguchi, Motomasa Furuse, Toshihiro Takami, Naonori Hu …

Biology, 12(9), Sep 15, 2023
Influence of lung physical density on dose calculation in boron neutron capture therapy for malignant pleural mesothelioma.

Hiroyuki Sato, Takushi Takata, Minoru Suzuki, Yoshinori Sakurai

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 198 110857-110857, Aug, 2023
5-Aminolevulinic acid increases boronophenylalanine uptake into glioma stem cells and may sensitize malignant glioma to boron neutron capture therapy.

Masao Fukumura, Naosuke Nonoguchi, Shinji Kawabata, Ryo Hiramatsu, Gen Futamura, Koji Takeuchi, Takuya Kanemitsu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki …

Scientific reports, 13(1) 10173-10173, Jun 22, 2023
Development of optimization method for uniform dose distribution on superficial tumor in an accelerator-based boron neutron capture therapy system

Akinori Sasaki, Naonori Hu, Nishiki Matsubayashi, Takushi Takata, Yoshinori Sakurai, Minoru Suzuki, Hiroki Tanaka

Journal of Radiation Research, Apr 26, 2023
Development and evaluation of dose calculation algorithm with a combination of Monte Carlo and point-kernel methods for boron neutron capture therapy.

Mai Nojiri, Takushi Takata, Naonori Hu, Yoshinori Sakurai, Minoru Suzuki, Hiroki Tanaka

Biomedical physics & engineering express, 9(3), Apr 6, 2023
Boron uptake of boronophenylalanine and the effect of boron neutron capture therapy in cervical cancer cells.

Shinichi Terada, Satoshi Tsunetoh, Yoshimichi Tanaka, Tomohito Tanaka, Hideki Kashiwagi, Takushi Takata, Shinji Kawabata, Minoru Suzuki, Masahide Ohmichi

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 197 110792-110792, Apr 3, 2023
Carcinogenesis Observed in the Spleens of Balb/c Mice After Head-neutron Irradiation

Yuko Kinashi, Takushi Takata, Yoshinori Sakurai, Hiroki Tanaka

ANTICANCER RESEARCH, 43 1455-1461, Mar, 2023 Peer-reviewed
Improved Boron Neutron Capture Therapy Using Integrin αvβ3-Targeted Long-Retention-Type Boron Carrier in a F98 Rat Glioma Model

Kohei Tsujino, Hideki Kashiwagi, Kai Nishimura, Ryo Kayama, Kohei Yoshimura, Yusuke Fukuo, Hiroyuki Shiba, Ryo Hiramatsu, Naosuke Nonoguchi, Motomasa Furuse …

Biology, 12(3) 377-377, Feb 27, 2023
Carborane bearing pullulan nanogel-boron oxide nanoparticle hybrid for boron neutron capture therapy.

Riku Kawasaki, Hidetoshi Hirano, Keita Yamana, Hinata Isozaki, Shogo Kawamura, Yu Sanada, Kaori Bando, Anri Tabata, Kouhei Yoshikawa, Hideki Azuma …

Nanomedicine : nanotechnology, biology, and medicine, 49 102659-102659, Feb 21, 2023
The impact of TP53 status of tumor cells including the type and the concentration of administered 10B delivery agents on compound biological effectiveness in boron neutron capture therapy.

Shin-Ichiro Masunaga, Yu Sanada, Takushi Takata, Hiroki Tanaka, Yoshinori Sakurai, Minoru Suzuki, Mitsunori Kirihata, Koji Ono

Journal of radiation research, 64(2) 399-411, Feb 10, 2023
Multi-Targeted Neutron Capture Therapy Combined with an 18 kDa Translocator Protein-Targeted Boron Compound Is an Effective Strategy in a Rat Brain Tumor Model.

Hideki Kashiwagi, Yoshihide Hattori, Shinji Kawabata, Ryo Kayama, Kohei Yoshimura, Yusuke Fukuo, Takuya Kanemitsu, Hiroyuki Shiba, Ryo Hiramatsu, Toshihiro Takami …

Cancers, 15(4), Feb 6, 2023
Characteristics of optically stimulated luminescent dosimeter of beryllium oxide in BNCT irradiation field

Nishiki Matsubayashi, Naonori Hu, Takushi Takata, Akinori Sasaki, Tetsuya Mukawa, Keita Suga, Yoshinori Sakurai, Hiroki Tanaka

Radiation Measurements, 161 106900-106900, Feb, 2023
Air ionization chamber combined with LiCaAlF6 scintillator for <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e326" altimg="si58.svg"><mml:mi>γ</mml:mi></mml:math>-ray dose evaluation in boron neutron capture therapy

Nishiki Matsubayashi, Naonori Hu, Takushi Takata, Akinori Sasaki, Mai Nojiri, Tetsuya Mukawa, Yoshinori Sakurai, Hiroki Tanaka

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 1047 167883-167883, Feb, 2023
Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation

Natsuko Kondo, Yoshinori Sakurai, Takushi Takata, Kuniyuki Kano, Kyo Kume, Munetoshi Maeda, Nobuhiko Takai, Shugo Suzuki, Fumihiro Eto, Kenji Kikushima …

Scientific Reports, 12(1) 8718-8718, Dec, 2022 Peer-reviewed
Measurements of γ-rays and neutrons in BNCT irradiation field using thermoluminescent phosphor

Kiyomitsu Shinsho, Ryoken Oh, Masaya Tanaka, Natsumi Sugioka, Hiroki Tanaka, Genichiro Wakabayashi, Takushi Takata, Weishan Chang, Shinnosuke Matsumoto, Go OKADA …

Japanese Journal of Applied Physics, 62(1) 010502-010502, Oct 3, 2022

Misc.

126

Attempts to enhance the anti-tumor effects of BNCT by targeting the tumor microenvironment

真田悠生, 高田卓志, 田中浩基, 櫻井良憲, 渡邉翼

KURNS-EKR (Web), (17), 2023
Examination of a Large-Area Thermal neutron flux distribution Measurements using Cr doped Al₂O₃ ceramic plates with Cd converter

佐々木瑛麻, 杉岡菜津美, 松本真之介, 田中浩基, 高田卓志, 渡辺賢一, 大島裕也, 若林源一郎, 眞正浄光

応用物理学会春季学術講演会講演予稿集(CD-ROM), 70th, 2023
Gamma dose evaluation method with BeO OSLD in BNCT

松林錦, 高田卓志, 呼尚徳, 笹木彬礼, 武川哲也, 菅啓大, 櫻井良憲, 田中浩基

KURNS-EKR (Web), (17), 2023
Study of dose distribution formation by neutron intensity-modulated irradiation method for accelerator-based BNCT

笹木彬礼, HU Naonori, HU Naonori, 高田卓志, 松林錦, 櫻井良憲, 鈴木実, 田中浩基

KURNS-EKR (Web), (17), 2023
BNCT照射場におけるBeO光刺激ルミネッセンス線量計の利用

松林錦, 高田卓志, 呼尚徳, 笹木彬礼, 武川哲也, 菅啓大, 櫻井良憲, 田中浩基

放射線(Web), 48(2), 2023
ラットを用いた脊髄神経膠腫に対するホウ素中性子捕捉療法の橋渡し研究

藤川喜貴, 川端信司, 香山諒, 辻野晃平, 柏木秀基, 福尾祐介, 平松亮, 高田卓志, 田中浩基, 鈴木実 …

日本分子脳神経外科学会プログラム・抄録集, 23rd, 2023
アルブミンを基盤としたホウ素中性子捕捉療法用DDS薬剤のラット悪性神経膠腫モデルを用いた基礎研究

辻野晃平, 川端信司, 柏木秀基, 香山諒, 藤川喜貴, 福尾祐介, 竹内孝治, 平松亮, 高田卓志, 田中浩基 …

日本分子脳神経外科学会プログラム・抄録集, 23rd, 2023
Cdコンバータを設置したクロム添加アルミナ熱蛍光線量計の中性子に対する線量応答性

王良健, 柳澤伸, 田中浩基, 高田卓志, 古場裕介, 田中誠也, 眞正浄光

放射線(Web), 47(3), 2022
Cr添加Al₂O₃熱蛍光板とCdコンバータを用いた熱中性子束分布測定の検討

杉岡菜津美, 田中誠也, 王良健, 田中浩基, 高田卓志, 張維珊, 眞正浄光

放射線(Web), 47(3), 2022
Evaluation of nanopaticulate L-BPA formulation on biodistribution of ¹⁰B after its administration to tumor-bearing mice

安藤徹, 市川秀喜, 鈴木実, 高田卓志, 櫻井良憲

粉体に関する討論会講演論文集, 59th, 2022
Basic research of boron neutron capture therapy using a novel boron compound targeted to integrin

辻野晃平, 川端信司, 柏木秀基, 吉村亘平, 香山諒, 福尾祐介, 金光拓也, 平松亮, 呼尚徳, 宮武伸一 …

日本脳腫瘍学会学術集会プログラム・抄録集, 40th, 2022
Development of albumin ligand-based boron carriers for neutron capture therapy

西村開, 盛田大輝, 盛田大輝, 岡田智, 岡田智, 三浦一輝, 三浦一輝, 柏木秀基, 福尾祐介, 松本孔貴 …

日本薬学会年会要旨集(Web), 142nd, 2022
Development of Fast Neutron Detection Method Discriminating Gamma-ray Events with Single Ionization Chamber in BNCT Field

MATSUBAYASHI Nishiki, SASAKI Akinori, NOJIRI Mai, KO Naonori, TAKATA Takushi, SAKURAI Yoshinori, TANAKA Hiroki

日本放射線技術学会総会学術大会予稿集, 78th, 2022
Study on the Improvement of Neutron Distribution by Overlapping of Irradiation Fields Using Intensity Moderators in Accelerator-based BNCT

SASAKI Akinori, TAKATA Takushi, HU Naonori, HU Naonori, MATSUBAYASHI Nishiki, NOJIRI Mai, SAKURAI Yoshinori, TANAKA Hiroki

日本放射線技術学会総会学術大会予稿集, 78th, 2022
Development of a Hybrid Detector for Simultaneous Measurement of Thermal Neutron Flux and γ-ray Dose Rate for Therapeutic

加藤寛明, 松林錦, 高田卓志, 武川哲也, 菅啓大, 櫻井良憲, 田中浩基

KURNS-EKR (Web), (15), 2022
Development of ionization chamber for fast neutron monitoring in accelerator-based BNCT

松林錦, 笹木彬礼, 高田卓志, 櫻井良憲, 田中浩基

KURNS-EKR (Web), (15), 2022
Study on improvement of neutron distribution by overlapping of irradiation fields using intensity modulators in accelerator-based BNCT

笹木彬礼, 高田卓志, HU Naonori, HU Naonori, 松林錦, 野尻摩依, 櫻井良憲, 田中浩基

KURNS-EKR (Web), (15), 2022
Thermal neutron flux distribution measurements using thermoluminescence phosphor Cr doped Al₂O₃ with Cd converter

杉岡菜津美, 王良健, 田中誠也, 若林源一郎, 田中浩基, 高田卓志, 眞正浄光

応用物理学会秋季学術講演会講演予稿集(CD-ROM), 82nd, 2021
Biological Effects on Blood Brain Barrier Induced by Particle Irradiation

近藤夏子, 櫻井良憲, 高田卓志, 前田宗利, 久米恭

若狭湾エネルギー研究センター研究年報, 23, 2021
Study of Optimal Irradiation Method for Superficial Tumors Using a Hydrogel Bolus in Cyclotron-based BNCT

SASAKI Akinori, TAKATA Takushi, TAMARI Yuki, WATANABE Tsubasa, HU Naonori, HU Naonori, KAWABATA Shinji, KUDO Yoshihiro, MITSUMOTO Toshinori, MATSUBAYASHI Nishiki …

日本放射線技術学会総会学術大会予稿集, 77th, 2021

Research Projects

Characterisation of semiconductor detector in neutron irradiation field

Kyoto University Institute for Integrated Radiation and Nuclear Science, Apr, 2024 - Mar, 2025

Hiroki Tanaka, Yoshinori Sakurai, Takushi Takata, Nishiki Matsubayashi, Anatoly Rozenfeld, Linh Tran
MC法とSuperPosition法を組合せたBNCT線量計算アルゴリズムの開発

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

高田卓志
最適線量分布を実現するBNCT用補償フィルター設計手法

科学研究費助成事業若手研究(B), 若手研究(B), 日本学術振興会, Apr, 2017 - Mar, 2021

高田卓志
Accuracy improvement for dose and beam-quality estimation of irradiation field for boron neutron capture therapy using dual phantom technique

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Sakurai Yoshinori
Beam-profile measurement method using radiation-induced coloration in irradiation field for boron neutron capture therapy

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Sakurai Yoshinori
Development of dosimetric evaluation method for BNCT by using 3D patient surface data

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Takata Takushi

Industrial Property Rights

特許第5464351号高速中性子の線量分布測定方法

高田卓志
特開2011-185600 高速中性子の線量分布測定方法

高田卓志

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