論文

査読有り
2015年1月

Sequential Synthesis of Coordination Polymersomes

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
  • Ryo Ohtani
  • ,
  • Munehiro Inukai
  • ,
  • Yuh Hijikata
  • ,
  • Tetsuya Ogawa
  • ,
  • Mikihito Takenaka
  • ,
  • Masaaki Ohba
  • ,
  • Susumu Kitagawa

54
4
開始ページ
1139
終了ページ
1143
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1002/anie.201408101
出版者・発行元
WILEY-V C H VERLAG GMBH

Novel organic-inorganic hybrid liposomes, so-called coordination polymersomes (CPsomes), with artificial domains that exhibit strong lateral cohesion were prepared by a three-step procedure that formed a coordinative interaction leading to a lipid bilayer. First, the lipophilic complex (dabco-C-18)[Mn(N)(CN)(4)(dabco-C-18)] (1; dabco-C-18(+)=1,4-diazabicyclo[2,2,2]octane-(CH2)(17)CH3 cation), was synthesized. 1 has a lipophilic alkyl tail part and a tetracyanometallate head group, which can be used for an expansion to two-dimensional coordination networks. Second, 1 and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine were mixed to prepare the liposomes. Finally, CPsomes were obtained by the addition of transition-metal ions (M) to form unilamellar faceted liposomes with plain CP raft domains with MnCNM linkages. The concentration of 1 influences the size of the CP raft domains and the shape of the CPsomes. The synthesis of coordination polymers in lipid bilayers is a novel approach for the construction of artificial architectures as raft domains, for example, in cell membranes.

Web of Science ® 被引用回数 : 10

リンク情報
DOI
https://doi.org/10.1002/anie.201408101
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000348372900009&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?eid=2-s2.0-84921056863&partnerID=MN8TOARS
URL
http://orcid.org/0000-0003-4830-6888

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