2012年12月
Photo-Controllable DNA Origami Nanostructures Assembling into Predesigned Multiorientational Patterns
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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- 巻
- 134
- 号
- 51
- 開始ページ
- 20645
- 終了ページ
- 20653
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ja307785r
- 出版者・発行元
- AMER CHEMICAL SOC
We demonstrate a novel strategy for constructing multidirectional programmed 2D DNA nanostructures in various unique patterns by introducing photoresponsive oligonucleotides (Azo-ODNs) into hexagonal DNA origami structures. We examined regulation of assembly and disassembly of DNA nanostructures reversibly by different photoirradiation conditions in a programmed manner. Azo-ODNs were incorporated to the hexagonal DNA origami structures, which were then employed as self-assembly units for building up nanosized architectures in regulated arrangements. By adjusting the numbers and the positions of Azo-ODNs in the hexagonal units, the specific nanostructures with face controlling can be achieved, resulting in construction of ring-shaped nanostructures. By combining DNA origami strategy with photoregulating system, remote controlling of assembly and disassembly of DNA nanostructures has been accomplished simply by photo irradiation.
- リンク情報
- ID情報
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- DOI : 10.1021/ja307785r
- ISSN : 0002-7863
- PubMed ID : 23210720
- Web of Science ID : WOS:000313154200018