2020年9月
Totally transparent hydrogel-based subdural electrode with patterned salt bridge
Biomedical Microdevices
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- 巻
- 22
- 号
- 3
- 開始ページ
- 57
- 終了ページ
- 57
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1007/s10544-020-00517-0
- 出版者・発行元
- Springer Science and Business Media LLC
A totally transparent subdural electrode was developed by embedding a conductive poly (vinyl alcohol) (PVA)-filled microchannel made of poly(dimethylsiloxane) (PDMS) into an another PVA hydrogel substrate. Tight bonding between the PVA substrate and the PDMS microchannel (salt bridge) was achieved by mechanical interlocking utilizing the microprotrusions formed on the microchannel. This simple method of bonding without the use of any additives such as silane molecules or nanofibers is very suitable for constructing biomedical devices. The salt bridge electrode (total thickness, ca. 1.5 mm) was sufficiently soft, and showed superior shape conformability that makes it an excellent choice as a subdural electrode used on the brain surface. In vivo measurement proved that the salt bridge electrode makes close contact to the exposed porcine brain and can record brain wave signals of frequencies 1 ~ 15 Hz. In addition, the high transparency of the electrode provided a clear view of the brain surface that would assist the effective surgical operation and optogenetic research.
- リンク情報
- ID情報
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- DOI : 10.1007/s10544-020-00517-0
- ISSN : 1387-2176
- eISSN : 1572-8781
- PubMed ID : 32827271