Tomonori Tamura

Profile Information

Affiliation: Kyoto University

J-GLOBAL ID: 201401054098801783
researchmap Member ID: 7000010395

Research Areas

Life sciences / Bioorganic chemistry /

Papers

Endogenous Cell-Surface Receptor Modification by Metal Chelation-Assisted Pyridinium Oxime Catalyst

Vikram Thimaradka, Hayata Utsunomiya, Tomonori Tamura, Itaru Hamachi

Organic Letters, 25(12) 2118-2122, Mar 22, 2023 Peer-reviewedCorresponding author
Organelle-selective click labeling coupled with flow cytometry allows pooled CRISPR screening of genes involved in phosphatidylcholine metabolism.

Masaki Tsuchiya, Nobuhiko Tachibana, Kohjiro Nagao, Tomonori Tamura, Itaru Hamachi

Cell metabolism, Mar 7, 2023
Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes

Chem, 9(2) 523-540, Feb, 2023 Peer-reviewed
Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes

Hiroshi Nonaka, Takeharu Mino, Seiji Sakamoto, Jae Hoon Oh, Yu Watanabe, Mamoru Ishikawa, Akihiro Tsushima, Kazuma Amaike, Shigeki Kiyonaka, Tomonori Tamura …

Chem, 9(2) 523-540, Feb, 2023 Peer-reviewed
Chemical biology tools for imaging-based analysis of organelle membranes and lipids

Tomonori Tamura, Itaru Hamachi

Current Opinion in Chemical Biology, 70 102182-102182, Oct, 2022 Peer-reviewedInvitedLead authorCorresponding author
Concomitant Mitral Regurgitation in Severe Aortic Stenosis-A Report From the CURRENT AS Registry

R Murai, Y Kawase, T Taniguchi, T Morimoto, K Kadota, M Ohya, T Shimada, T Maruo, Y Fuku, T Komiya …

CIRCULATION JOURNAL, 86(3) 427-+, Mar, 2022
システイン以外のアミノ酸残基を標的とする不可逆阻害薬

田村朋則

日本薬理学雑誌, 157(5) 383-383, 2022
Light-induced stabilization of microtubules by photo-crosslinking of a Tau-derived peptide

Soei Watari, Hiroshi Inaba, Tomonori Tamura, Arif Md. Rashedul Kabir, Akira Kakugo, Kazuki Sada, Itaru Hamachi, Kazunori Matsuura

Chemical Communications, 2022 Peer-reviewedInvited
Organelle‐Selective Labeling of Choline‐Containing Phospholipids (CPLs) and Real‐Time Imaging in Living Cells

Masaki Tsuchiya, Tomonori Tamura, Itaru Hamachi

Current Protocols, 1(4), Apr 22, 2021 Peer-reviewedInvited
Enhanced Suppression of a Protein–Protein Interaction in Cells Using Small-Molecule Covalent Inhibitors Based on an N-Acyl-N-alkyl Sulfonamide Warhead

Tsuyoshi Ueda, Tomonori Tamura, Masaharu Kawano, Keiya Shiono, Fruzsina Hobor, Andrew J. Wilson, Itaru Hamachi

Journal of the American Chemical Society, 143(12) 4766-4774, Mar 31, 2021 Corresponding author
オルガネラ膜特異的なホスファチジルコリンのライブイメージング

田村朋則, 浜地格

実験医学, 39 594-600, 2021
Site-specific covalent labeling of His-tag fused proteins with N-acyl-N-alkyl sulfonamide reagent

Vikram Thimaradka, Jae Hoon Oh, Christina Heroven, A. Radu Aricescu, Michisuke Yuzaki, Tomonori Tamura, Itaru Hamachi

Bioorganic & Medicinal Chemistry, 30 115947-115947, Jan, 2021 Corresponding author
Organelle membrane-specific chemical labeling and dynamic imaging in living cells

Tomonori Tamura, Alma Fujisawa, Masaki Tsuchiya, Yuying Shen, Kohjiro Nagao, Shin Kawano, Yasushi Tamura, Toshiya Endo, Masato Umeda, Itaru Hamachi

Nature Chemical Biology, 16(12) 1361-1367, Dec, 2020 Lead author
Imaging and Profiling of Proteins under Oxidative Conditions in Cells and Tissues by Hydrogen-Peroxide-Responsive Labeling

Hao Zhu, Tomonori Tamura, Alma Fujisawa, Yuki Nishikawa, Rong Cheng, Mikiko Takato, Itaru Hamachi

Journal of the American Chemical Society, 142(37) 15711-15721, Sep 16, 2020
Chemical Tools for Endogenous Protein Labeling and Profiling

Kazuki Shiraiwa, Rong Cheng, Hiroshi Nonaka, Tomonori Tamura, Itaru Hamachi

CELL CHEMICAL BIOLOGY, 27(8) 970-985, Aug, 2020 Peer-reviewed
Development of a Photoactivatable Proximity Labeling Method for the Identification of Nuclear Proteins

Tomonori Tamura, Mikiko Takato, Keiya Shiono, Itaru Hamachi

CHEMISTRY LETTERS, 49(2) 145-148, Feb, 2020 Peer-reviewed
Development of a Cell-Based Ligand-Screening System for Identifying Hsp90 Inhibitors

Tsuyoshi Ueda, Tomonori Tamura, Itaru Hamachi

BIOCHEMISTRY, 59(2) 179-182, Jan, 2020 Peer-reviewed
Development of a Nitric Oxide-Responsive Labeling Reagent for Proteome Analysis of Live Cells.

Yuki Nishikawa, Takayuki Miki, Masashi Awa, Keiko Kuwata, Tomonori Tamura, Itaru Hamachi

ACS chemical biology, 14(3) 397-404, Mar 15, 2019 Peer-reviewed
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.

Naoya Shindo, Hirokazu Fuchida, Mami Sato, Kosuke Watari, Tomohiro Shibata, Keiko Kuwata, Chizuru Miura, Kei Okamoto, Yuji Hatsuyama, Keisuke Tokunaga …

Nature chemical biology, 15(3) 250-258, Mar, 2019 Peer-reviewed
Chemistry for Covalent Modification of Endogenous/Native Proteins: From Test Tubes to Complex Biological Systems

Tomonori Tamura, Itaru Hamachi

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 141(7) 2782-2799, Feb, 2019 Peer-reviewed

Misc.

生体金属動態の分子科学-「生命金属科学」への展開コンディショナルプロテオミクスによる亜鉛関連タンパク質群の同定

田村朋則, 三木卓幸, 西川雄貴, 清中茂樹, 若林真樹, 石濱泰, 浜地格

生命科学系学会合同年次大会, 2017年度 [1PW06-4], Dec, 2017
コンディショナルプロテオミクスによる亜鉛関連タンパク質群の同定

田村朋則, 三木卓幸, 西川雄貴, 清中茂樹, 若林真樹, 石濱泰, 浜地格, 浜地格

日本生化学会大会(Web), 90th ROMBUNNO.1PW06‐4 (WEB ONLY), 2017
4価型人工ペプチドを用いたホスファチジン酸結合プローブの開発

小川莉奈, 長尾耕治郎, 原雄二, 田村朋則, 浜地格, 井上飛鳥, 青木淳賢, 高橋美帆, 西川喜代孝, 梅田真郷

脂質生化学研究, 57 170-173, May, 2015

Books and Other Publications

生命金属ダイナミクス : 生体内における金属の挙動と制御

古川, 良明, 神戸, 大朋, 城, 宜嗣, 津本, 浩平 (Role: Contributor)

エヌ・ティー・エス, Jan, 2021 (ISBN: 9784860437060)

Research Projects

オルガネラ代謝物の化学標識による時空間メタボローム解析

科学研究費助成事業, 基盤研究(B), 日本学術振興会, Apr, 2021 - Mar, 2025

田村朋則
生命金属動態の理解に向けた金属イオンConditionalプロテオミクス法の開発

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Jun, 2019 - Mar, 2024

田村朋則
Development of a novel chemical modification method to enable electron microscopic observation of voltage-dependent calcium channels

Grants-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2020

Tamura Tomonori
Development of novel protein chemical modification method for imaging analysis of endogenous protein-protein interaction in live cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2017

Tamura Tomonori
Development of a technique for selective chemical labeling and modification of intracellular proteins

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, Nov, 2011 - Mar, 2014

TSUKIJI Shinya, HAMACHI Itaru, TAMURA Tomonori, ISHIDA Manabu, KIKUCHI Tamaki
LDT化学による新しい細胞内蛋白質間相互作用解析技術の開発

科学研究費助成事業, 特別研究員奨励費, 日本学術振興会, 2010 - 2012

田村朋則

Profile Information

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