2021年4月
Dirhodium-Catalyzed Chemo- and Site-Selective C–H Amidation of N,N-Dialkylanilines
Synlett
- ,
- ,
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- 巻
- 32
- 号
- 07
- 開始ページ
- 728
- 終了ページ
- 732
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1055/a-1334-6450
- 出版者・発行元
- Georg Thieme Verlag KG
<title>Abstract</title>A method for dirhodium-catalyzed C(sp3)–H amidation of N,N-dimethylanilines was developed. Chemoselective C(sp3)–H amidation of N-methyl group proceeded exclusively in the presence of C(sp2)–H bonds of the electron-rich aromatic ring. Site-selective C(sp3)–H amidation proceeded exclusively at the N-methyl group of N-methyl-N-alkylaniline derivatives with secondary, tertiary, and benzylic C(sp3)–H bonds α to a nitrogen atom.
- リンク情報
- ID情報
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- DOI : 10.1055/a-1334-6450
- ISSN : 0936-5214
- eISSN : 1437-2096