PUJALS Silvia RIATOS (Silvia Pujals-riatos) - マイポータル

基本情報

所属: 京都大学

J-GLOBAL ID: 201401065837751600
researchmap会員ID: 7000010536

論文

Effect of the Attachment of a Penetration Accelerating Sequence and the Influence of Hydrophobicity on Octaarginine-Mediated Intracellular Delivery

Kentaro Takayama, Hisaaki Hirose, Gen Tanaka, Silvia Pujals, Sayaka Katayama, Ikuhiko Nakase, Shiroh Futaki

MOLECULAR PHARMACEUTICS 9(5) 1222-1230 2012年5月査読有り
Transient Focal Membrane Deformation Induced by Arginine-rich Peptides Leads to Their Direct Penetration into Cells

Hisaaki Hirose, Toshihide Takeuchi, Hiroko Osakada, Silvia Pujals, Sayaka Katayama, Ikuhiko Nakase, Shouhei Kobayashi, Tokuko Haraguchi, Shiroh Futaki

MOLECULAR THERAPY 20(5) 984-993 2012年5月査読有り
Transformation of an antimicrobial peptide into a plasma membrane-permeable, mitochondria-targeted peptide via the substitution of lysine with arginine

Ikuhiko Nakase, Shinya Okumura, Sayaka Katayama, Hisaaki Hirose, Silvia Pujals, Hirofumi Yamaguchi, Satoko Arakawa, Shigeomi Shimizu, Shiroh Futaki

CHEMICAL COMMUNICATIONS 48(90) 11097-11099 2012年査読有り
Electrochemical Investigation of Cellular Uptake of Quantum Dots Decorated with a Proline-Rich Cell Penetrating Peptide

Sergio Marin, Silvia Pujals, Ernest Giralt, Arben Merkoci

BIOCONJUGATE CHEMISTRY 22(2) 180-185 2011年2月査読有り
Homogeneous Conjugation of Peptides onto Gold Nanoparticles Enhances Macrophage Response

Neus G. Bastus, Ester Sanchez-Tillo, Silvia Pujals, Consol Farrera, Carmen Lopez, Ernest Giralt, Antonio Celada, Jorge Lloberas, Victor Puntes

ACS NANO 3(6) 1335-1344 2009年6月査読有り
Cytosolic Targeting of Macromolecules Using a pH-Dependent Fusogenic Peptide in Combination with Cationic Liposomes

Sachiko Kobayashi, Ikuhiko Nakase, Noriko Kawabata, Hao-Hsin Yu, Silvia Pujals, Miki Imanishi, Ernest Giralt, Shiroh Futaki

BIOCONJUGATE CHEMISTRY 20(5) 953-959 2009年5月査読有り
Shuttling Gold Nanoparticles inside Tumoral Cells with an Amphipathic Pro-rich Peptide.

Pujals, S, Gómez-Bastús, N, Pereiro, E, López, C, F. Puntes, V, Kogan, M.J, Giralt, E

ChemBioChem, 10(6), 1025–1031, (2009). 2009年4月17日査読有り
A proline-rich peptide improves cell transfection of solid lipid nanoparticle-based non-viral vectors for gene therapy.

Pozo-Rodriguez, A, Pujals, S, Delgado, D, Solinis, M.A, Gascon, A.R, Giralt, E, Pedraz, J.L

Journal of Controlled Release, 133(1) 52-59, (2009). 2009年1月5日査読有り
Proline-rich, amphipathic cell-penetrating peptides

Silvia Pujals, Ernest Giralt

ADVANCED DRUG DELIVERY REVIEWS 60(4-5) 473-484 2008年3月査読有り
all-D proline-rich cell-penetrating peptides: a preliminary in vivo internalization study.

Pujals, S, Sabido, E, Tarrago, T, Giralt, E

Biochemical Society Transactions, 35 (4), 794-796, (2007). 2007年8月査読有り
Replacement of a proline with silaproline causes a 20-fold increase in the cellular uptake of a pro-rich peptide

S Pujals, J Fernandez-Carneado, MJ Kogan, J Martinez, F Cavelier, E Giralt

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 128(26) 8479-8483 2006年7月査読有り

MISC

Custom engineering of natural mesoscale-materials for targeted drug and gene-delivery, part 2: Electron microscopic evaluation of polyarganine-derivatized hemocyanins as improved adjuvants and immunogens.

Silvia Pujals-Riatos, Azumi Yoshimura, Ikuhiko Nakase, Nobuhiro Morone, Shiroh Futaki, John. E. Heuser

6th Annual Symposium on Nanobiotechnology, Kyoto Cell-Material Integration, Shiran Kaikan, Kyoto University, Japan. 2012年11月8日
Elucidating effects of amphipathic peptides on cell-membrane architecture

Pujals, S, Taniuchi, K, Miyamae, H, Umeda, M, Futaki, S

5th International Peptide Symposium, Kyoto, Japan 2010年12月4日
Amphipathic Pro-rich peptides: efficient and protease stable CPPs able to transport intracellularly different cargoes.

Pujals, S, Fernandez-Carneado, J, Giralt, E

CPP Satellite Meeting of the 30th European Peptide Symposium, Helsinki, Finland. 2008年9月
Amphipathic Pro-rich cell-penetrating peptides as intracellular drug delivery systems

Pujals, S, Fernandez-Carneado, J, Giralt, E

30th European Peptide Symposium, Helsinki, Finland. 2008年9月
Amphipathic Pro-rich peptides as intracellular drug delivery systems

Pujals, S. Fernandez-Carneado, J, Giralt, E

3rd Western Mediterranean Meeting, Montpellier, France. 2007年
Amphipathic Pro-rich peptides with increased metabolic stability

Pujals, S, Fernandez-Carneado, J, Kogan, M.J, Giralt, E

10th Iberian Peptide Meeting, Universidad de Zaragoza, Zaragoza, Spain. 2006年2月1日
Pro-rich cell-penetrating peptides. Study of the influence of D-amino acids

Pujals, S, Fernandez-Carneado, J, Kogan, M.J, Giralt, E

2nd West Mediterranean Chemistry Meeting, Universitat de Girona, Platja d’Aro, Spain. 2005年6月3日
Pro-rich cell-penetrating peptides. Study of the influence of D-amino acids”

Pujals, S, Fernandez-Carneado, J, Kogan, M.J, Giralt, E

VIth EuropeanSymposium of the Protein Society, Protein Society, Barcelona, Spain. 2005年4月10日

講演・口頭発表等

Epsin derived amphipathic peptide as positive membrane curvature promoter

The 5th “MEXT Project of Integrated Research on Chemical Synthesis” Forum, Unique peptide assemblies with biological functions 2012年9月15日
Membrane active peptides: from cell-penetrating peptides to membrane curvature inducing peptides

Frontier Research Center For Post-Genome Science and Technology, Special Lecture. 2011年9月26日
Expressed Protein Ligation with Cell Penetrating Peptides: a means of endotoxin-free fusion proteins’ preparation

455th WE-Heraeus-Seminar, Biophysics of Membrane-Active Peptides 2010年4月11日 Physikzentrum Bad Honnef, Germany.
Amphipathic Pro-rich cell-penetrating peptides: from development to cargo transport

Institute for Research in Biomedicine seminars, Chemistry and Molecular Pharmacology Program 2008年7月10日
Carrying gold nanoparticles inside the cell.

XXII Scientific Meeting of the Mediterranean, Nanoscience and Nanotechnology. 2006年

産業財産権

特許 08382058.9-1216 (European patent) Conjugates having colloidal stability in a medium comprising nanoparticles coated with peptides

Neus G. Bastus, Ester Sanchez-Tillo, Silvia Pujals, Consol Farrera, Ernest Giralt, Antonio Celada, Jorge Lloberas, Victor Puntes