室伏善照 (Yoshiteru Murofushi) - マイポータル

基本情報

所属: 名古屋大学大学院医学系研究科

J-GLOBAL ID: 201401055282392493
researchmap会員ID: 7000010577

研究分野

ライフサイエンス / 腫瘍生物学 /

経歴

京都大学

論文

Transgelin defines pro-tumorigenic cancer-associated fibroblasts in pancreatic cancer

Xingxing Wang, Keiko Shinjo, Kohei Kumegawa, Reo Maruyama, Shinji Mii, Yukihiro Shiraki, Tastunori Nishimura, Yoshiteru Murofushi, Miho Suzuki, Takanobu Kabasawa …

British Journal of Cancer 134(4) 577-588 2025年12月16日
A stress granule-associated RNA-binding protein FAM120A drives cisplatin resistance in non-small cell lung cancer.

Shunsaku Hayai, Miho M Suzuki, Kenta Iijima, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Tatsunori Nishimura, Makoto Ishii, Yutaka Kondo

Journal of biochemistry 2025年12月2日
Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma.

Keiko Shinjo, Takashi Umehara, Hideaki Niwa, Shin Sato, Keisuke Katsushima, Shinya Sato, Xingxing Wang, Yoshiteru Murofushi, Miho M Suzuki, Hiroo Koyama …

Cancer gene therapy 31(12) 1884-1894 2024年12月
TUG1-mediated R-loop resolution at microsatellite loci as a prerequisite for cancer cell proliferation.

Miho M Suzuki, Kenta Iijima, Koichi Ogami, Keiko Shinjo, Yoshiteru Murofushi, Jingqi Xie, Xuebing Wang, Yotaro Kitano, Akira Mamiya, Yuji Kibe …

Nature communications 14(1) 4521-4521 2023年8月22日
Fusobacterium infection facilitates the development of endometriosis through the phenotypic transition of endometrial fibroblasts.

Ayako Muraoka, Miho Suzuki, Tomonari Hamaguchi, Shinya Watanabe, Kenta Iijima, Yoshiteru Murofushi, Keiko Shinjo, Satoko Osuka, Yumi Hariyama, Mikako Ito …

Science translational medicine 15(700) eadd1531 2023年6月14日
Newly established patient-derived organoid model of intracranial meningioma.

Shintaro Yamazaki, Fumiharu Ohka, Masaki Hirano, Yukihiro Shiraki, Kazuya Motomura, Kuniaki Tanahashi, Takashi Tsujiuchi, Ayako Motomura, Kosuke Aoki, Keiko Shinjo …

Neuro-oncology 23(11) 1936-1948 2021年11月2日
Cancer-Specific Targeting of Taurine-Upregulated Gene 1 Enhances the Effects of Chemotherapy in Pancreatic Cancer.

Yoshihiko Tasaki, Miho Suzuki, Keisuke Katsushima, Keiko Shinjo, Kenta Iijima, Yoshiteru Murofushi, Aya Naiki-Ito, Kazuki Hayashi, Chenjie Qiu, Akiko Takahashi …

Cancer research 81(7) 1654-1666 2021年4月1日
A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer.

Keiko Shinjo, Kazuo Hara, Genta Nagae, Takayoshi Umeda, Keisuke Katsushima, Miho Suzuki, Yoshiteru Murofushi, Yuta Umezu, Ichiro Takeuchi, Satoru Takahashi …

PloS one 15(6) e0233782 2020年
Deletion of caveolin scaffolding domain alters cancer cell migration.

Sunaho Okada, Sadaf A Raja, Jonathan Okerblom, Aayush Boddu, Yousuke Horikawa, Supriyo Ray, Hideshi Okada, Itta Kawamura, Yoshiteru Murofushi, Fiona Murray …

Cell cycle (Georgetown, Tex.) 18(11) 1268-1280 2019年6月
Development of ghrelin transgenic mice for elucidation of clinical implication of ghrelin.

Daisuke Aotani, Hiroyuki Ariyasu, Satoko Shimazu-Kuwahara, Yoshiyuki Shimizu, Hidenari Nomura, Yoshiteru Murofushi, Kentaro Kaneko, Ryota Izumi, Masaki Matsubara, Hajime Kanda …

Endocrine journal 64(Suppl.) S31-S33 2017年
Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias.

Toshitaka Yajima, Yoshiteru Murofushi, Hanbing Zhou, Stanley Park, Jonathan Housman, Zhao-Hua Zhong, Michinari Nakamura, Mitsuyo Machida, Kyung-Kuk Hwang, Yusu Gu …

Circulation 124(24) 2690-701 2011年12月13日
Efficacy of autologous fat injection laryngoplasty with an adenoviral vector expressing hepatocyte growth factor in a canine model.

H Umeno, S Chitose, Y Murofushi, K Kosai, K Sato, A Kawahara, T Nakashima

The Journal of laryngology and otology. Supplement (31) 24-9 2009年
Cell cycle-specific changes in hTERT promoter activity in normal and cancerous cells in adenoviral gene therapy: a promising implication of telomerase-dependent targeted cancer gene therapy.

Yoshiteru Murofushi, Satoshi Nagano, Junichi Kamizono, Tomoyuki Takahashi, Hisayoshi Fujiwara, Setsuro Komiya, Toyojiro Matsuishi, Ken-ichiro Kosai

International journal of oncology 29(3) 681-8 2006年9月
In vivo hepatic HB-EGF gene transduction inhibits Fas-induced liver injury and induces liver regeneration in mice: a comparative study to HGF.

Ngin Cin Khai, Tomoyuki Takahashi, Hiroaki Ushikoshi, Satoshi Nagano, Kentaro Yuge, Masayasu Esaki, Takao Kawai, Kazuko Goto, Yoshiteru Murofushi, Takako Fujiwara …

Journal of hepatology 44(6) 1046-54 2006年6月
Local overexpression of HB-EGF exacerbates remodeling following myocardial infarction by activating noncardiomyocytes.

Hiroaki Ushikoshi, Tomoyuki Takahashi, Xuehai Chen, Ngin Cin Khai, Masayasu Esaki, Kazuko Goto, Genzou Takemura, Rumi Maruyama, Shinya Minatoguchi, Takako Fujiwara …

Laboratory investigation; a journal of technical methods and pathology 85(7) 862-73 2005年7月
Adenoviral gene transduction of hepatocyte growth factor elicits inhibitory effects for hepatoma.

Kentaro Yuge, Tomoyuki Takahashi, Satoshi Nagano, Yasuhiro Terazaki, Yoshiteru Murofushi, Hiroaki Ushikoshi, Takao Kawai, Ngin Cin Khai, Toshikazu Nakamura, Hisayoshi Fujiwara …

International journal of oncology 27(1) 77-85 2005年7月
Survivin-responsive conditionally replicating adenovirus exhibits cancer-specific and efficient viral replication.

Junichi Kamizono, Satoshi Nagano, Yoshiteru Murofushi, Setsuro Komiya, Hisayoshi Fujiwara, Toyojiro Matsuishi, Ken-ichiro Kosai

Cancer research 65(12) 5284-91 2005年6月15日

共同研究・競争的資金等の研究課題

疾患特異的iPS細胞を用いたヒト遺伝性腫瘍疾患モデルの構築

日本学術振興会科学研究費助成事業若手研究(B) 2015年4月 - 2017年3月

室伏善照
ライブラリースクリーニングを用いたCRPCに対する新規創薬標的分子の探索

日本学術振興会科学研究費助成事業挑戦的萌芽研究 2014年4月 - 2016年3月

中村英二郎, 室伏善照, 井上貴博
エピジェネティック制御異常に着目した腎細胞癌の新規治療標的分子の探索

日本学術振興会科学研究費助成事業若手研究(B) 2013年4月 - 2015年3月

室伏善照
小児の固形癌への革新的遺伝子治療法となる増殖制御型アデノウイルスの開発

日本学術振興会科学研究費助成事業基盤研究(B) 2007年 - 2009年

小戝健一郎, 小宮節郎, 河野嘉文, 高橋知之, 前薗理恵, 室伏善照