SAKASEGAWA Yuji

J-GLOBAL         Last updated: Sep 4, 2017 at 16:44
 

Academic & Professional Experience

 
 
   
 
Assistant Professor, Tohoku University Graduate School of Medicine
 
2005
   
 
- Graduate School of Medical Science, Graduate school of Tohoku University Assistant professor
 

Awards & Honors

 
2013
APPS 2013 Selected Poster Award
 

Misc

 
Nishizawa, Keiko Oguma, Ayumi Kawata, Maki Sakasegawa, Yuji Teruya, Kenta Doh-ura, Katsumi
J Virol   88(8) 4083-4099   2014
Detection of Proteinase K - resistant p rion protein (PrPres) in mouse neuroblastoma cells
倉橋洋史 逆瀬川裕二 堂浦克美
蛋白質科学会アーカイブ   7 e074   2014
Dominant negative inhibition by GPI anchor-less recombinant prion proteins is observed in persistently prion infected N2a cells in a culture medium-dependent manner.
Sakasegawa, Y Goto, Y Hachiya, N Kaneko, K Doh-Ura, K
PRION   6 29-29   2012
[Creutzfeldt-Jakob disease and its therapeutic approaches].
Sakasegawa, Yuji Doh-Ura, Katsumi
Nihon Rinsho   69 Suppl 10(Pt 2) 411-414   2011
プリオン病の疫学から治療まで プリオン病の分子標的治療薬の開発
逆瀬川 裕二 木村 朋寛 堂浦 克美
NEUROINFECTION   16(1) 79-86   2011

Conference Activities & Talks

 
A platinum compound enhances the protease sensitivity of PrPres in cell lysates
APPS2014   2014   
Cell biology and biochemistry for prion regulation
第86回日本生化学会大会   2013   
Glycerol enhances the PrPres production via a PI3K signaling pathway in prion-infected neuroblastoma cells
APPS2013   2013   
Extracellular heat shock protein 90 enhances PrPres production in prion-infected neuroblastoma
APPS2012   2012   
Dominant negative inhibition by GPI anchor-less recombinant prion proteins is observed in persistently prion infected N2a cells in a culture medium-dependent manner.
Neuroprion2012   2012   

Works

 
BSE発症前診断に役立つバイオ代理マーカー
2008 - 2013
Development of herbal cure for prion and Alzheimer's diseases
2008 - 2014
プリオン病に関わる細胞内因子の探索とプリオン病発症機序の解明
2005 - 2014
Elucidation of the mechanism of action of anti-prion compounds related to quinacrine
2009 - 2011
DNAアプタマーを用いた組織上の蛋白質検出法の開発
2005 - 2007

Research Grants & Projects

 
Development of therapeutics and diagnostics for prion diseases
Basic Science Research Program
Project Year: 2005