論文

査読有り 国際誌
2007年5月7日

Involvement of hippocampal metabotropic glutamate receptors in radial maze performance.

Neuroreport
  • Kazuko Hayashi
  • ,
  • Toru Yoshihara
  • ,
  • Yukio Ichitani

18
7
開始ページ
719
終了ページ
23
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1097/WNR.0b013e3280d9e880
出版者・発行元
LIPPINCOTT WILLIAMS & WILKINS

We investigated the role of hippocampal metabotropic glutamate receptors in spatial learning and memory, using an eight-arm radial maze task. (S)-4-Carboxyphenylglycine, a group I metabotropic glutamate receptor antagonist, or trans-(+/-)-1-amino-(1S,3R)-cyclopentanedicarboxylic acid, a broad-spectrum metabotropic glutamate receptor agonist, was administered into the dorsal hippocampus after rats had acquired the task. Both of these agents significantly impaired radial maze performance, suggesting a functional importance of hippocampal metabotropic glutamate receptors in spatial working memory.

Web of Science ® 被引用回数 : 7

リンク情報
DOI
https://doi.org/10.1097/WNR.0b013e3280d9e880
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/17426606
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000245856000020&DestApp=WOS_CPL
ID情報
  • DOI : 10.1097/WNR.0b013e3280d9e880
  • ISSN : 0959-4965
  • PubMed ID : 17426606
  • Web of Science ID : WOS:000245856000020

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