We proposed a plasmonic-WGM hybrid system composed of a tapered-fiber-coupled microsphere resonator and a PIC-attached gold tip to focus the incident light into a nanoscale domain(similar to 728.8 nm(2)) with high coupling efficiency of similar to 80.3 % and the Q factor of similar to 1.9x10(6). In order to experimentally verify the strong interaction between light and matter owing to efficient excitation of localized surface plasmon at the gold-coated tip, we demonstrated to observe two-photon excited fluorescence from PIC dye molecules attached on the gold-coated tip even under a weak CW excitation condition via a tapered-fiber-coupled microsphere resonator.