Hayata Tadayoshi

J-GLOBAL         Last updated: May 1, 2019 at 21:20
 
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Name
Hayata Tadayoshi
E-mail
hayata.tadayoshi.mphrs.tus.ac.jp
Affiliation
Tokyo University of Science
Section
Faculty of Pharmaceutical Sciences Department of Medicinal and Life Science
Job title
Associate Professor
Degree
PhD(The University of Tokyo)
Research funding number
40420252

Research Areas

 
 

Academic & Professional Experience

 
Sep 2005
 - 
Apr 2014
Assistant Professor, Medical Research Institute, Tokyo Medical & Dental University
 
Jan 2008
 - 
Mar 2008
Visiting Scholar, Department of Genetics, Harvard Medical School
 
Apr 2002
 - 
Aug 2005
Postgraduate Researcher, Department of Developmental & Cell Biology, University of California, Irvine
 
Jun 2001
 - 
Mar 2002
Department of Developmental & Cell Biology, University of California, Irvine
 

Education

 
Apr 1994
 - 
Mar 1996
Department of Biology (animal), Faculty of Science, The University of Tokyo
 
Apr 1996
 - 
Mar 1998
Department of Life Sciences, Master course, Graduate School of Arts and Sciences, The University of Tokyo
 
Apr 1998
 - 
Mar 2001
Department of Life Sciences, Doctor course, Graduate School of Arts and Sciences, The University of Tokyo
 

Awards & Honors

 
Aug 2015
OUTSTANDING POSTER AWARD, 12th Bone Biology Forum
 

Published Papers

 
Hayashi N, Sato T, Yumoto M, Kokabu S, Fukushima Y, Kawata Y, Kajihara T, Mizuno Y, Mizuno Y, Kawakami T, Kirita T, Hayata T, Noda M, Yoda T
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology      Jan 2019   [Refereed]
Hayata T, Chiga M, Ezura Y, Asashima M, Katabuchi H, Nishinakamura R, Noda M.
Genes Cells   23(5) 345-356   May 2018   [Refereed]
In mammals, the ovarian follicles are regulated at least in part by bone morphogenetic protein (BMP) family members. Dullard (also known as Ctdnep1) gene encodes a phosphatase that suppresses BMP signaling by inactivating or degrading BMP receptor...
Kajikawa S, Taguchi Y, Hayata T, Ezura Y, Ueta R, Arimura S, Inoue JI, Noda M, Yamanashi Y
Biochemical and biophysical research communications   498(4) 967-974   Apr 2018   [Refereed]
Kawasaki,M;Izu,Y;Hayata,T;Ideno,H;Nifuji,A;Sheffield,VC;Ezura,Y;Noda,M
Bone   101 179-190   Aug 2017   [Refereed]
Nakamoto,T;Izu,Y;Kawasaki,M;Notomi,T;Hayata,Tadayoshi;Noda,M;Ezura,Y
J Cell Biochem   117(4) 970-977   Apr 2016   [Refereed]
Aryal,A C S;Miyai,K;Izu,Y;Hayata,Tadayoshi;Notomi,T;Noda,M;Ezura,Y
Proc Natl Acad Sci U S A.   112(50) 15432-15437   Dec 2015   [Refereed]
Kawasaki,M;Ezura,Y;Hayata,T;Notomi,T;Izu,Y;Noda,M
J Cell Physiol   230(11) 2788-2795   Nov 2015   [Refereed]
Yamada,T;Ezura,Y;Hayata,Tadayoshi;Moriya,S;Shirakawa,J;Notomi,T;Arayal,S;Kawasaki,M;Izu,Y;Harada,K;Noda,M
J Cell Biochem   116(6) 1144-1152   Jun 2015   [Refereed]
再生医療と幹細胞
早田,匡芳;浅島誠
日本臨牀 再生医療   1080 40-46   Jun 2015
Hayata,Tadayoshi;Ezura,Y;Asashima,M;Nishinakamura,R;Noda,M
J Bone Miner Res   30(2) 318-29   Feb 2015   [Refereed]
Ezura,Y;Nagata,J;Nagao,M;Hemmi,H;Hayata,T;Rittling,S;Denhardt,DT;Noda,M
J Bone Miner Metab   33(1) 48-54   Jan 2015
Moriya,S;Hayata,Tadayoshi;Notomi,T;Aryal,S;Namamoto,T;Izu,Y;Kawasaki,M;Yamada,T;Shirakawa,J;Kaneko,K;Ezura,Y;Noda,M
J Cell Biochem   116(1) 142-8   Jan 2015   [Refereed]
Shirakawa,J;Ezura,Y;Moriya,S;Kawasaki,M;Yamada,T;Notomi,T;Nakamoto,T;Hayata,Tadayoshi;Miyawaki,A;Omura,K;Noda,M
J Cell Physiol   229(10) 1353-1358   Oct 2014   [Refereed]
骨におけるメッセンジャーRNAの安定性と生体制御について
野田,政樹;早田,匡芳;渡辺,千穂;白川,純平;守屋,秀一;山田,峻之;江面,陽一
生物の科学 遺伝   68(5) -458   Sep 2014
Watanabe,C;Morita,M;Hayata,T;Nakamoto,T;Kikuguchi,C;Li,X;Kobayashi,Y;Takahashi,N;Notomi,T;Moriyama,K;Yamamoto,T;Ezura,Y;Noda,M
Proc Natl Acad Sci U S A   111(7) 2692-7   Feb 2014   [Refereed]
Aryal,AC;Miyai,K;Hayata,Tadayoshi;Notomi,T;Nakamoto,T;Pawson,T;Ezura,Y;Noda,M
J Cell Physiol   228(7) 1397-1403   Jul 2013   [Refereed]
Suzuki,T;Notomi,T;Miyajima,D;Mizoguchi,F;Hayata,T;Nakamoto,T;Hanyu,R;Kamolratanakul,P;Mizuno,A;Suzuki,M;Ezura,Y;Izumi,Y;Noda,M
Bone   54(1) 172-178   May 2013   [Refereed]
III. 骨研究フロンティア-基礎から臨床まで- 骨形成・骨吸収における関連因子の働き PTH
野田政樹;江面陽一;早田,匡芳;守屋秀一;白川純平;Smriti,Aryal;納富拓也;渡辺千穂;長尾雅史;羽生亮
日本臨牀 最新の骨粗鬆症学—骨粗鬆症の最新知見—   71(2) 161-166   Apr 2013
Miyajima,D;Hayata,Tadayoshi;Suzuki,T;Hemmi,H;Nakamoto,T;Notomi,T;Amagasa,T;Böttcher,RT;Costell,M;Fässler,R;Ezura,Y;Noda,M
J Biol Chem   287(40) 33545-33553   Sep 2012   [Refereed]
骨のメカノバイオロジー
野田政樹;江面陽一;早田,匡芳;納富拓也;中元哲也;渡辺千穂;Smriti,Aryal A.C.
細胞工学   31(9) 1030-32   Sep 2012

Conference Activities & Talks

 
Profilin1 deficiency in osteoclasts causes osteolytic developmental bone deformities due to increased osteoclast movements and differentiation.
Kajikawa S, Shirakawa J, Hayata T, Izu Y, Böttcher RT, Costell M, Noda M, Ezura Y
2 Sep 2018   
Profilin1 negatively regulates osteoclast migration in postnatal skeletal growth and remodeling in mice.
15th Bone Biology Forum   17 Aug 2018   
破骨細胞遊走を抑制するプロフィリン1の遺伝子欠損は骨吸収亢進を伴う骨格形成障害を引き起こす
江面, 陽一;白川, 純平;ベッチャー, ラルフ;Hayata, Tadayoshi;野田, 政樹
2017年度生命科学系学会合同年次大会   6 Dec 2017   
分子生物学的アプローチによる運動器研究の新展開:イントロダクション
早田, 匡芳
2017年度生命科学系学会合同年次大会   8 Dec 2017   
Dullard deficiency causes hemorrhage in the adult ovarian follicles.
Hayata, Tadayoshi;Masahiko C, Ezura Y, Asashima M, Katabuchi H, Nishinakamura R, Noda M
第50回日本発生生物学会   11 May 2017   
Skeletal anomaly caused by the phosphatase Dullard gene deficiency is ameliorated by administration of TGF-β receptor inhibitor.
早田,匡芳;江面,陽一;浅島,誠;西中村,隆一;野田,政樹
第90回日本薬理学会年会   15 Mar 2017   
Profilin1 Deficiency in Osteoclasts Causes Osteolytic Erlenmeyer-Flask Deformity of the Femurs Due to the Increased Migratory Potential.
Shirakawa,J;Ezura,Y;Hayata,Tadayoshi;Izu,Y;Botcher,R;Fässler,R;Noda,M
American Society for Bone and Mineral Research   16 Sep 2016   
Osteoclasts require the Profilin1 for postnatal skeletal growth, remodeling and homeostasis.
Shirakawa,J;Böttcher,RT;Hayata,Tadayoshi;Izu,Y;Fässler,R;Noda,M;Ezura,Y
The Joint Annual Scientific Meetings of the Endocrine Society of Australia and the Society for Reproductive Biology and the Australian and New Zealand Bone and Mineral Society   21 Aug 2016   
Dullard/Ctdnep1遺伝子は、TGF-βシグナルの抑制を介して、内軟骨性骨化を制御する [Invited]
早田,匡芳;江面,陽一;浅島,誠;西中村,隆一;野田,政樹
第21回日本軟骨代謝学会   19 Feb 2016   
Dokアダプターによる破骨細胞の分化制御機構
梶川,修平;田口,祐;早田,匡芳;江面,陽一;有村,純暢;井上,純一郎;野田,政樹;山梨,裕司
第38回 日本分子生物学会年会   1 Dec 2015   
Ciliary Protein BBS3 is required for normal patterning of cranial base.
Kawasaki,M;Hayata,Tadayoshi;Izu,Y;Ezura,Y;Noda,M
Australian and New Zealand Bone and Mineral Society Annual Scientific Meeting 2015   1 Nov 2015   
副甲状腺ホルモン(PTH)による骨量増加作用に対するTobの機能解析 [Invited]
守屋,秀一;早田,匡芳;伊豆,弥生;江面,陽一;鈴木,亨;金子,和夫;山本,雅;野田,政樹
第30回日本整形外科学会基礎学術集会   22 Oct 2015   
Bardet-Biedl Syndrome 3 Is Involved in the Development of Cranial Base.
Kawasaki,M;Hayata,Tadayoshi;Izu,Y;Ezura,Y;Noda,M
American Society for Bone and Mineral Reserch 2015 Annual Meeting   9 Oct 2015   
Interleukin-1β Suppresses Expression of Osteoblastic Genes as well as the Regulators of Ecto-nucleotides and Pyrophosphate That Negatively Regulate Bio-mineralization in Mouse Bone Marrow Stromal Cells.
Ezura,Y;Hatta,A;Shin,L;Izu,Y;Hayata,Tadayoshi;Noda,M
American Society for Bone and Mineral Reserch 2015 Annual Meeting   9 Oct 2015   
Negative regulation of TGF-β signaling by Dullard is required for endochondral ossification.
Hayata,Tadayoshi;Ezura,Y;Asashima,M;Nishinakamura,R;Noda,M
12th Bone Biology Forum   21 Aug 2015   
一次繊毛関連分子BBS3の頭蓋顔面領域における骨格形成制御
川崎,真希理;早田,匡芳;伊豆,弥生;江面,陽一;野田,政樹
第33回日本骨代謝学会学術集会   23 Jul 2015   
β2-adrenergic receptor expression in osteoblastic MC3T3-E1 cells is regulated by PTH
Moriya,S;Hayata,Tadayoshi;Yamada,T;Shirakawa,J;Kawasaki,M;Kaneko,K;Ezura,Y;Noda,M
13th Congress of the International Society of Bone Morphometry   27 Apr 2015   
BMP-induced alkaline phosphatase expression in osteoblast-like MC3T3E1 cells is suppressed by β2 adrenergic receptor activation
Yamada,T;Ezura,Y;Hayata,Tadayoshi;Moriya,S;Shirakawa,J;Notomi,T;Aryal,S;Kawasaki,M;Izu,Y;Harada,K;Noda,M
13th Congress of the International Society of Bone Morphometry   27 Apr 2015   
TGF-beta impairs cilia morphology via suppression of Ift88 expression in chondrocytic ATDC5 cells.
Kawasaki,M;Hayata,Tadayoshi;Nakamoto,T;Notomi,T;Moriya,S;Yamada,T;Izu,Y;Ezura,Y;Noda,M
13th Congress of the International Society of Bone Morphometry   27 Apr 2015   
Morphological and dynamic analysis of migration linked to FUCCI-indicated cell cycle under the influence of PTH and mechanical flow signals.
Shirakawa,J;Ezura,Y;Moriya,S;Kawasaki,M;Yamada,T;Notomi,T;Hayata,Tadayoshi;Miyawaki,A;Omura,K;Noda,M
13th Congress of the International Society of Bone Morphometry   27 Apr 2015   

Teaching Experience

 
 

Others

 
Peer-review
Journal of Bone and Mineral Research, International Journal of Developmental Biology, KEIO SFC Journal, Regenerative Therapy