論文

査読有り 筆頭著者 責任著者 本文へのリンクあり 国際誌
2021年9月

Cross-sectional assessment of sleep and fatigue in middle-aged Japanese women with primary Sjogren syndrome or rheumatoid arthritis using self-reports and wrist actigraphy

Medicine (Baltimore)
  • Miyauchi K
  • ,
  • Fujimoto K
  • ,
  • Abe T
  • ,
  • Takei M
  • ,
  • Ogawa K

17;100(37):e27233.
37
開始ページ
1
終了ページ
7
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1097/MD.0000000000027233.

ABSTRACT: To investigate fatigue, health-related quality of life (HR-QOL), and sleep quality in women with primary Sjogren syndrome (pSS) or rheumatoid arthritis (RA) as compared with healthy controls using self-reports and wrist actigraphy.In this cross-sectional observational study, we evaluated a total of 25 patients (aged 40-75 years) with pSS, 10 with RA, and 17 healthy control subjects living in Japan. The HR-QOL was assessed using the Short Form-36. Fatigue was evaluated using the Short Form-36 vitality score, visual analog scale (VAS) for fatigue, and 2 questionnaire items using scores based on a 4-point Likert scale. Sleep quality was measured using the Japanese version of the Pittsburgh Sleep Quality Index, VAS for sleep quality, and wrist actigraphy for 14 days.Patients with pSS reported severer fatigue and lower HR-QOL than healthy controls, especially in mental health. Based on the Pittsburgh Sleep Quality Index score, 56% of the patients with pSS were poor sleepers, which was higher than healthy controls (29.4%). Furthermore, the patients with pSS scored significantly lower on the VAS for sleep quality than healthy controls (40.5 vs 63.7, P = .001). Although subjective assessments revealed slight sleep disturbances in patients with pSS, wrist actigraphy revealed no differences when compared with healthy controls for total sleep time (421.8 minutes vs 426.5 minutes), sleep efficiency (95.2% vs 96.4%), number of awakenings (1.4 vs 0.9), and wake after sleep onset (22.4 minutes vs 16.1 minutes). Poor subjective sleep quality was associated with enhanced fatigue. However, sleep efficiency, as determined by actigraphy, was not associated with fatigue. Notably, the patients with RA and healthy controls did not differ significantly in terms of fatigue or sleep quality, although patients with RA experienced more nocturnal awakenings than healthy controls (1.7 vs 0.9, P = .04).Patients with pSS experience severe fatigue, poor HR-QOL, and sleep disturbances, which are associated with fatigue. However, wrist actigraphy did not reveal differences in sleep quality, suggesting that it may not be an appropriate measure of sleep in patients with pSS.

リンク情報
DOI
https://doi.org/10.1097/MD.0000000000027233. 本文へのリンクあり
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34664865
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448038
共同研究・競争的資金等の研究課題
リウマチ性疾患を持つ中高年女性の睡眠の質と慢性疲労の評価
URL
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8448038/ 本文へのリンクあり
ID情報
  • DOI : 10.1097/MD.0000000000027233.
  • PubMed ID : 34664865
  • PubMed Central 記事ID : PMC8448038

エクスポート
BibTeX RIS