MISC

2017年9月

Is there an obesity paradox in the Japanese elderly population? A community-based cohort study of 13 280 men and women

GERIATRICS & GERONTOLOGY INTERNATIONAL
  • Kenji Yamazaki
  • ,
  • Etsuji Suzuki
  • ,
  • Takashi Yorifuji
  • ,
  • Toshihide Tsuda
  • ,
  • Toshiki Ohta
  • ,
  • Kazuko Ishikawa-Takata
  • ,
  • Hiroyuki Doi

17
9
開始ページ
1257
終了ページ
1264
記述言語
英語
掲載種別
DOI
10.1111/ggi.12851
出版者・発行元
WILEY

AimDespite increased interest in an obesity paradox (i.e. a survival advantage of being obese), evidence remains sparse in Japanese populations. We aimed to verify this phenomenon among community-dwelling older adults in Japan.
MethodsOlder adults aged 65-84 years randomly chosen from all 74 municipalities in Shizuoka Prefecture completed questionnaires including body mass index information. Participants were followed from 1999 to 2009. Following World Health Organization guidelines, participants were classified using an appropriate body mass index for Asian populations as follows: <18.5 kg/m(2) (underweight), 18.5-23.0 kg/m(2) (normal weight), 23.0-27.5 kg/m(2) (overweight) and 27.5 kg/m(2) (obesity). We estimated hazard ratios and their 95% confidence intervals for all-cause mortality, controlling for sex, age, smoking status, alcohol consumption, physical activity, hypertension and diabetes mellitus.
ResultsCompared with normal-weight participants, overweight/obese participants tended to have lower hazard ratios; the multivariate hazard ratios (95% confidence interval) were 0.86 (0.62-1.19) for obesity, 0.83 (0.73-0.94) for overweight and 1.60 (1.40-1.82) for underweight. In subgroup analyses by sex and age, the hazard ratios tended to be lower among obese men, albeit not significantly; hazard ratios (95% confidence interval) were 0.56 (0.25-1.27) in men aged 65-74 years, and 0.78 (0.41-1.45) in men aged 75-84 years.
ConclusionsThe present study provides evidence of a conservative obesity paradox among older Japanese people, using the appropriate body mass index cut-off points for Asian populations. In particular, obese older men tend to have a lower risk of all-cause mortality. Geriatr Gerontol Int 2017; 17: 1257-1264.

Web of Science ® 被引用回数 : 22

リンク情報
DOI
https://doi.org/10.1111/ggi.12851
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000412071800003&DestApp=WOS_CPL

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