Aoki Hitomi

J-GLOBAL         Last updated: Dec 11, 2019 at 02:48
Aoki Hitomi
Gifu University

Research Areas


Published Papers

Sugiyama K, Nagashima K, Miwa T, Shimizu Y, Kawaguchi T, Iida K, Tamaoki N, Hatakeyama D, Aoki H, Abe C, Morita H, Kunisada T, Shibata T, Fukumitsu H, Tezuka KI
Journal of bone and mineral metabolism   37(3) 467-474   May 2019   [Refereed]
Taguchi N, Hata T, Kamiya E, Kobayashi A, Aoki H, Kunisada T
Journal of dermatological science   92(3) 286-289   Dec 2018   [Refereed]
Aoki H
Medical molecular morphology   51(3) 129-138   Sep 2018   [Refereed]
Ibaraki K, Mizuno M, Aoki H, Niwa A, Iwamoto I, Hara A, Tabata H, Ito H, Nagata KI
Acta histochemica et cytochemica   51(3) 119-128   Jun 2018   [Refereed]
Nakamura M, Suetsugu A, Hasegawa K, Matsumoto T, Aoki H, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM
Journal of cellular biochemistry   118(12) 4216-4221   Dec 2017   [Refereed]
Aoki H, Hara A, Kunisada T
JCI insight   2(19)    Oct 2017   [Refereed]
Nakamura M, Suetsugu A, Hasegawa K, Matsumoto T, Aoki H, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM
Anticancer research   37(7) 3429-3434   Jul 2017   [Refereed]
Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Aoki H, Kunisada T, Shimizu M, Saji S, Moriwaki H, Hoffman RM
Anticancer research   37(7) 3435-3440   Jul 2017   [Refereed]
Hashimoto K, Yamada Y, Semi K, Yagi M, Tanaka A, Itakura F, Aoki H, Kunisada T, Woltjen K, Haga H, Sakai Y, Yamamoto T, Yamada Y
Proceedings of the National Academy of Sciences of the United States of America   114(4) 758-763   Jan 2017   [Refereed]
Yuriguchi M, Aoki H, Taguchi N, Kunisada T
Journal of dermatological science   84(1) 80-87   Oct 2016   [Refereed]
Matsumoto T, Suetsugu A, Hasegawa K, Nakamura M, Shibata Y, Aoki H, Kunisada T, Tsurumi H, Shimizu M, Bouvet M, Hoffman RM
Anticancer research   36(9) 4483-4487   Sep 2016   [Refereed]
Imaging Nuclear-Cytoplasmic Dynamics in Primary and Metastatic Colon Cancer in Nude Mice.
Hasegawa K, Suetsugu A, Nakamura M, Matsumoto T, Aoki H, Kunisada T, Bouvet M, Shimizu M, Hoffman RM
Anticancer research   36(5) 2113-2117   May 2016   [Refereed]
Color-Coded Imaging of Syngeneic Orthotopic Malignant Lymphoma Interacting with Host Stromal Cells During Metastasis.
Matsumoto T, Suetsugu A, Hasegawa K, Nakamura M, Aoki H, Kunisada T, Tsurumi H, Shimizu M, Hoffman RM
Anticancer research   36(4) 1473-1478   Apr 2016   [Refereed]
Aoki H, Ogino H, Tomita H, Hara A, Kunisada T
PloS one   11(9) e0163042   2016   [Refereed]
Hitomi Aoki Takahiro Kunisada
pigment cell and melanoma research      Jun 2013
Aoki Hitomi, Hara Akira, Motohashi Tsutomu, Kunisada Takahiro
J Invest Dermatol.      Apr 2013
Yoshimura N, Motohashi T, Aoki H, Tezuka K, Watanabe N, Wakaoka T, Era T, Kunisada T
Dev Growth Differ   55(2) 270-281   Jan 2013
Takamatsu M, Aoki H, Hirose Y, Kobayashi K, Tomita H, Kuno T, Koumura H, Hara A.
Oncol Lett.   3(5) 1023-1026   May 2012
Aoki H, Hara A, Era T, Kunisada T, Yamada Y.
Development   139(4) 667-677   Feb 2012
Hatano Y, Yamada Y, Hata K, Phutthaphadoong S, Aoki H, Hara A.
Cancer Sci.   102(9) 1659-1664   Sep 2011
Aoki H, Hara A, Era T, Kunisada T, Yamada Y.
Development.   131(9) 1906-1914   Sep 2011
Motohashi T, Yamanaka K, Chiba K, Miyajima K, Aoki H, Hirobe T, Kunisada T.
Dev Dyn.   240(7) 1681-1693   Jul 2011
Aoki H, Hara A, Motohashi T, Osawa M, Kunisada T.
Pigment Cell Melanoma Res.   24(1) 125-135   Feb 2011
Tamaoki Naritaka(dental suegery),Tezuka Kenichi(Tissue and Organ Develpment),Aoki Hitomi(Tissue and Organ development),Kunisada Takahiro(Tissue andOrgan Development),Takahashi Kazutoshi(Kyoto University),Ichisaka Tomoko(kyoto University),Takeda Tomoko(Dental Surgery),IIda Kazuki(Dental Surgery),Shibata Toshiyuki(Dental Surgery),Shinya Yamanaka(Kyouto University)
89(8) 773-778   Jun 2010
Hara A, Taguchi A, Aoki H, Hatano Y, Niwa M, Yamada Y, Kunisada T.
477(3) 138-143   Jan 2010
Motohashi T, Yamanaka K, Chiba K, Aoki H, Kunisada T.
Stem Cells.   27(4) 888-897   Apr 2009
Suetsugu A, Nagaki M, Aoki H, Motohashi T, Kunisada T, Moriwaki H.
Transplantation.   86(9) 1178-1186   Nov 2008
Niwa M, Hara A, Taguchi A, Aoki H, Kozawa O, Mori H
Neurol Res.   31(7) 721-727   Sep 2008
Hara A, Aoki H, Taguchi A, Niwa M, Yamada Y, Kunisada T, Mori H.
17(4) 619-628   Aug 2008
Tsuji Y, Yoshimura N, Aoki H, Sharov AA, Ko MS, Motohashi T, Kunisada T.
Dev Dyn   237(8) 2129-2138   Aug 2008
Aoki H, Kunisada T.
21(3) 338-339   Jun 2008
Transplantation of melanocytes into iris: method for iris repigmentation.
Aoki H, Yoshida H, Hara A, Suzuki T, Kunisada T.
85(3) 492-494   Feb 2008
Soeda A, Inagaki A, Oka N, Ikegame Y, Aoki H, Yoshimura SI, Nakashima S, Kunisada T, Iwama T.
. J Biol Chem   29(3) 666-672   2008


Takuro Matsumoto, Atsushi Suetsugu, Atsushi Suetsugu, Atsushi Suetsugu, Yuhei Shibata, Nobuhiko Nakamura, Hitomi Aoki, Takahiro Kunisada, Hisashi Tsurumi, Masahito Shimizu, Robert M. Hoffman, Robert M. Hoffman
Anticancer Research   35 4647-4654
Aim: A syngeneic color-coded imageable lymphoma model has been developed to visualize recruitment of host stromal cells by malignant lymphoma during metastasis. The EL4 cell line was previously derived from a lymphoma induced in a C57/BL6 mouse by...
Akira Hara, Masayuki Niwa, Masayuki Niwa, Hitomi Aoki, Masako Kumada, Takahiro Kunisada, Takeru Oyama, Tetsuya Yamamoto, Osamu Kozawa, Hideki Mori
Brain Research   1109 192-200
Retinal photoreceptor cell degeneration was induced by cobalt chloride, a chemical hypoxia-mimicking agent in rodents. Time course and dose-response of photoreceptor cell degeneration in mouse retina after intravitreal injection of cobalt chloride...
Hitomi Aoki, Akira Hara, Masayuki Niwa, Tsutomu Motohashi, Takashi Suzuki, Takahiro Kunisada
Experimental Eye Research   84 868-875
The aim of this study was to investigate the developmental potential of embryonic stem (ES) cell-derived eye-like structures as a replacement cell therapy model for retinas with N-methyl-d-aspartate (NMDA)-induced damage. For this purpose mouse ES...
T. Mizuno, N. Suzuki, H. Makino, T. Furui, E. Morii, H. Aoki, T. Kunisada, M. Yano, S. Kuji, Y. Hirashima, A. Arakawa, S. Nishio, K. Ushijima, K. Ito, Y. Itani, K. Morishige
Gynecologic Oncology   137 299-305
© 2014 Elsevier Inc. Objective. In ovarian cancer cases, recurrence after chemotherapy is frequently observed, suggesting the involvement of ovarian cancer stem-like cells (CSCs). The chemoresistance of ovarian clear cell carcinomas is particularl...
Atsushi Suetsugu, Masahito Nagaki, Hitomi Aoki, Tsutomu Motohashi, Takahiro Kunisada, Hisataka Moriwaki
Biochemical and Biophysical Research Communications   351 820-824
The CD133 antigen, identified as a hematopoietic stem cell marker, appears in various human embryonic epithelia including the neural tube, gut, and kidney. We herein investigated whether CD133+ cells isolated from human hepatocellular carcinoma ce...

Conference Activities & Talks

第26回日本色素細胞学会   2015   日本色素細胞学会
Rest function in neuronal or neural crest cell lineage revealed by the conditional gene ablation
第58回日本神経化学会大会   2015   日本神経化学会
Keratinocyte stem cells as a primary target for radiation-induced hair graying
第24回日本色素細胞学会   2012   日本色素細胞学会
Rest is dispensable for the proper intrinsic regulations of neuronal gene expression in the specification of cell fate during neurogenesis in vivo
第44回日本発生生物学会年会   2011   日本発生生物学会
第23回日本色素細胞学会   2010   日本色素細胞学会
第9回 日本再生医療学会総会   2010   日本再生医療学会
ヒトES 細胞の眼胞様構造へのin vitro 及びin vivo 分化系
第113回日本眼科学会総会   2009   日本眼科学会
第8回 日本再生医療学会総会   2009   日本再生医療学会
第22回日本色素細胞学会   2008   日本色素細胞学会
眼球の前房における免疫特権を活かしたマウスES細胞由来色素細胞の移植による虹彩の有色化とin vivoにおける分化制御
第29回日本炎症・再生医学会   2008   日本炎症・再生医学会
第112回日本眼科学会総会   2008   日本眼科学会
第7回 日本再生医療学会総会   2008   日本再生医療学会
眼、ハーダー腺, 耳の色素細胞の維持機構:皮膚の色素細胞とのc-kitとendothelin 3シグナルに対する感受性の比較
第21回日本色素細胞学会   2007   日本色素細胞学会
第28回 日本炎症・再生医学会   2007   日本炎症・再生医学会
第111回日本眼科学会総会   2007   日本眼科学会
日本眼科学会専門別研究会   2007   日本眼科学会専門別研究会
ES細胞由来細胞の色素細胞への分化〜鶏胚と成体マウスの目におけるin vivoでの解析〜
第20回日本色素細胞学会   2006   日本色素細胞学会
第19回日本色素細胞学会   2005   日本色素細胞学会
第4回日本再生医療学会   2005   日本再生医療学会
第18回日本色素細胞学会   2004   日本色素細胞学会
第17回日本色素細胞学会   2003   日本色素細胞学会

Research Interests


Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2010 - 2011    Investigator(s): Hitomi AOKI
In the present study, we have generated Rest conditional knockout mice, which allow the effect of genetic ablation of Rest during embryonic neurogenesis to be examined in vivo. We show that Rest plays a role in suppressing the expression of neuron...
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: 2013 - 2014
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: 2013 - 2014

Social Contribution

日経ヘルス 2019年2月号 白髪ケア革命2019
[Commentator]  日経BP  (64-75ページ)  2019 - 2019
[Commentator, Media coverage cooperation, Advisor, Informant]  日刊ゲンダイ  2018 - 2018
et Rouge No.17 2018年白髪研究最前線。
[Media coverage cooperation, Advisor, Informant]  日経BP  (70-74ページ)  2018 - 2018
研究現場発 REST遺伝子の多彩な機能
[Informant, Contribution]  中部経済新聞  2017 - 2017
再生医療を目指した基礎研究の現状 - iPS細胞とES細胞・幹細胞生物学 ー
[Lecturer, Advisor]  岐阜市産学官連携事業  平成25年度 「岐阜市ヒ_シ_ネススクール」  (JR 岐阜駅内 ハートフルスクエアー G 2F 中研修室)  2013 - 2013