INABA Kenji

J-GLOBAL         Last updated: Apr 26, 2019 at 10:22
 
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Name
INABA Kenji
URL
http://db.tohoku.ac.jp/whois/e_detail/9a4e9bbe892d39ecd2bcf123aac9befc.html
Affiliation
Tohoku University
Section
Institute of Multidisciplinary Research for Advanced Materials Division of Organic- and Bio-materials Research Biomolecular Structure
Job title
Professor

Research Areas

 
 

Academic & Professional Experience

 
Apr 2013
 - 
Today
professor, Tohoku University
 
Dec 2006
 - 
Mar 2013
associate professor, Kyushu University
 

Education

 
Apr 1988
 - 
Mar 1993
Kyoto University
 

Published Papers

 
Structural basis of sarco/endoplasmic reticulum Ca2+-ATPase 2b regulation via transmembrane helix interplay
Inoue, M., Sakuta, N., Watanabe, S., Zhang, Y., Yoshikaie, K., Tanaka, Y., Ushioda, R., Kato, Y., Takagi, J., Tsukazaki, T., Nagata, K. and Inaba, K.*
Cell Reports   27 1221-1230   Apr 2019   [Refereed]
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway
Watanabe S., Amagai Y., Sannino S., Tempio T., Anelli T., Harayama M., Masui S., Sorrentino I., Yamada M., Sitia R, and Inaba K*
Nature Communications   10(1) 603   Feb 2019   [Refereed]
Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding
Okada, S., Matsusaki, M., Arai, K., Hidaka, Y., Inaba, K., Okumura, M. and Muraoka, T.
Chem. Commun.   55(6) 759-762   Jan 2019   [Refereed]
Dynamic assembly of protein disulfide isomerase in catalysis of oxidative folding
Okumura, M., Noi, K., Kanemura, S., Kinoshita, M., Saio, T., Inoue, Y., Hikima, T., Akiyama, S., Ogura, T. and Inaba, K.*
Nature Chemical Biology   15 499-509   Mar 2019   [Refereed]
Characterization and optimization of two-chain folding pathways of insulin via native chain assembly
Arai, K., Takei, T., Shinozaki, R., Noguchi, M., Fujisawa, S., Katayama, H., Moroder, M., Ando, S., Okumura, M., Inaba, K., Hojo, H. and Iwaoka, M.
Cummunications Chemistry   26 1-15   May 2018   [Refereed]
Ero1-mediated reoxidation of PDI accelerates the folding of cone snail
O'Brien, H., Kanemura, S., Okumura, M., Baskin, P., Bandyopadhyay, P., Ellgaard, L., Inaba, K. and Safavi-Hemami, H.
Int. J. Mol. Sci.   19(11) E3418   Oct 2018   [Refereed]
Methods to identify the substrates of thiol-disulfide oxidoreductases
Fujimoto, T., Inaba, K. and Kadokura, H.
Protein Science   28(1) 30-40   Jan 2019   [Refereed]
Identification of the physiological substrates of PDIp, a pancreas-specific protein disulfide isomerase family member protein, from a mouse tissue
Fujimoto, T., Nakamura, O., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K. and Kdokura, H.
J. Biol. Chem.   293(48) 18421-18433   Nov 2018   [Refereed]
Akaike T, Ida T, Wei FY, Nishida M, Kumagai Y, Alam MM, Ihara H, Sawa T, Matsunaga T, Kasamatsu S, Nishimura A, Morita M, Tomizawa K, Nishimura A, Watanabe S, Inaba K, Shima H, Tanuma N, Jung M, Fujii S, Watanabe Y, Ohmuraya M, Nagy P, Feelisch M, Fukuto JM, Motohashi H
Nature Communications   8(1) 1177   Oct 2017   [Refereed]
Maegawa KI, Watanabe S, Noi K, Okumura M, Amagai Y, Inoue M, Ushioda R, Nagata K, Ogura T, Inaba K*
Structure (London, England : 1993)   25(6) 846-857.e4   Jun 2017   [Refereed]
Arai K, Takei T, Okumura M, Watanabe S, Amagai Y, Asahina Y, Moroder L, Hojo H*, Inaba K.*, Iwaoka M.* (*co-corresponding authors)
Angewandte Chemie (International ed. in English)   56(20) 5522-5526   May 2017   [Refereed]
Watanabe S, Harayama M, Kanemura S, Sitia R, Inaba K.*
Proceedings of the National Academy of Sciences of the United States of America   114(16) E3224-E3232   Apr 2017   [Refereed]
Kanemura, S., Okumura, M., Yutani, K., Ramming, T., Hikima, T., Appenzeller-Herzog, C., Akiyama, S., Inaba, K.*
J. Biol. Chem.   291(46) 23952-23964   Nov 2016   [Refereed]
8830
Ushioda R, Miyamoto A, Inoue M, Watanabe S, Okumura M, Maegawa KI, Uegaki K, Fujii S, Fukuda Y, Umitsu M, Takagi J, Inaba K, Mikoshiba K, Nagata K
Proceedings of the National Academy of Sciences of the United States of America   113(41) E6055-E6063   Oct 2016   [Refereed]
Cao, Z, van Lith, M., Mitchell, L. J., Pringle, M. A., Inaba, K., Bulleid, N. J.
Biochem. J   473(7) 851-858   Apr 2016   [Refereed]
8639
Ramming, T., Kanemura, S., Okumura, M., Inaba, K.*, Appenzeller-Herzog, C.* (*co-corresponding authors)
Redox Biology   7 14-20   Apr 2016   [Refereed]
8638
Murata A, Ito Y, Kashima R, Kanbayashi S, Nanatani K, Igarashi C, Okumura M, Inaba K, Tokino T, Takahashi S, Kamagata K
Journal of molecular biology   427(16) 2663-2678   Aug 2015   [Refereed]
Watanabe, S., Kawashima, T., Nishitani, Y., Kanai, T., Wada, T., Inaba, K., Atomi, H., Imanaka, T., Miki, K.
Proc. Natl. Acad. Sci. USA.   112 7701-7706   Jun 2015   [Refereed]
8635
Okumura M, Kadokura H, Inaba K.*
Free Radical Biology & Medicine   83 314-322   Jun 2015   [Refereed]
Ramming, T., Okumura, M., Kanemura, S., Baday, S., Birk, J., Moes, S., Spiess, M., Jeno, P., Berneche, S., Inaba, K., Appenzeller-Herzog, C.
Free Radical Biology & Medicine   83 361-372   Jun 2015   [Refereed]
8634
Sannino, S., Anelli, T., Cortini, M., Masui, S., Degano, M., Fagioli, C, Inaba, K., Sitia, R.
Journal of Cell Science   127(19) 4260-4269   Oct 2014   [Refereed]
8038
Okumura, M.,Kadokura, K., Hashimoto, S., Yutani, K., Kanemura, S., Hikima, T., Hidaka, Y., Ito, L., Shiba, K., Masui, S., Imai, D., Imaoka, S., Yamaguchi, H., Inaba, K.*
Journal of Biological Chemistry   289(39) 27004-27018   Sep 2014   [Refereed]
8037
Kojima, R., Okumura, M., Masui, S., Kanemura, S., Inoue, M., Saiki, M., Yamaguchi, H., Hikima, T., Suzuki, M., Akiyama, S., Inaba, K.*
Structure   22 431-443   Mar 2014   [Refereed]
7803
Appenzeller-Herzog, C., Inaba, K., Delaunay-Moisan, A.
Int. J. Cell Biol.   2014 157038-157039   Feb 2014
Walden, P. M., Halili, M. A., Archbold, J. K., Lindahl, F., Fairlie, D. P., Inaba, K.*, Martin, J. L.* (*co-corresponding authors)
PLoS One   8(11) e81440   Nov 2013   [Refereed]
7800
Kadokura, H., Saito, M., Tsuru, A., Hosoda, A., Iwawaki, T., Inaba, K. Kohno, K.
Biochem. Biophys. Res. Comm.   440(2) 245-250   Oct 2013   [Refereed]
7802
Structural basis of disulfide bond formation in the bacterial periplasm and ER.
Kojima, R., Okumura, M., Inaba, K.*
Encyclopedia of Life Science   10(1002)    Sep 2013
Sato, Y., Kojima, R., Okumura, M., Hagiwara, M., Masui, S., Maegawa, K., Saiki, M., Horibe, T., Suzuki, M., Inaba, K.*
Scientific Reports   3(2456) 10.1038   Aug 2013   [Refereed]
7799
Vavassori, S., Cortini, M., Masui, S., Sannino, S., Anelli, T., Caserta, I. R., Fagioli, C., Fornili, A., Mossuto, M. F., Degano, M, Inaba, K., Sitia, R.
Molecular Cell   50(6) 783-792   Jun 2013   [Refereed]
7801
Bisphenol A induces a conformational change in protein disulfide isomerase.
Okumura, M., Hashimoto, S., Nawata, M., Yutani, K., Hikima, T., Hamada, D., Hidaka, Y., Ito, L., Shiba, K., Hosokawa, K., Inoue, T., Maekawa, S., Imaoka, S., Inaba, K., Yamaguchi, H.
Peptide Science   331-332   Jun 2013   [Refereed]
7804
Sato Y, Inaba K.*
The FEBS journal   279(13) 2262-2271   Jul 2012   [Refereed]
Araki K, Inaba K.*
Antioxidants & redox signaling   16(8) 790-799   Apr 2012   [Refereed]
Ishitani, S., Inaba, K., Matsumoto, K. and Ishitani, T.
Mol. Biol. Cell   22 266-277   2011   [Refereed]
Hagiwara, M., Maegawa, K., Suzuki, M., Ushioda, R., Araki, K., Matsimoto, Y., Hoseki, J., Nagata, K.* and Inaba, K.*
Molecular Cell   41 432-444   2011   [Refereed]
Masui, S., Vavassori, S., Fagioli, C., Sitia, R. and Inaba, K.*
J. Biol. Chem.   286 16262-16271   2011   [Refereed]
Inaba K.*, Masui S, Iida H, Vavassori S, Sitia R, Suzuki M
The EMBO journal   29(19) 3330-3343   Oct 2010   [Refereed]
Inaba K.*
Genes to cells : devoted to molecular & cellular mechanisms   15(9) 935-943   Sep 2010   [Refereed]
Serve O, Kamiya Y, Maeno A, Nakano M, Murakami C, Sasakawa H, Yamaguchi Y, Harada T, Kurimoto E, Yagi-Utsumi M, Iguchi T, Inaba K, Kikuchi J, Asami O, Kajino T, Oka T, Nakasako M, Kato K
Journal of molecular biology   396(2) 361-374   Feb 2010   [Refereed]
Inaba K.*
Journal of biochemistry   146(5) 591-597   Nov 2009   [Refereed]
Inaba K.*, Murakami S, Nakagawa A, Iida H, Kinjo M, Ito K, Suzuki M
The EMBO journal   28(6) 779-791   Mar 2009   [Refereed]
Ito K, Inaba K
Current opinion in structural biology   18(4) 450-458   Aug 2008   [Refereed]
Inaba K.*
Journal of synchrotron radiation   15(Pt 3) 199-201   May 2008   [Refereed]
Inaba K, Ito K
Biochimica et biophysica acta   1783(4) 520-529   Apr 2008   [Refereed]
Inaba, K., Suzuki, M. Maegawa, K., Akiyama, S., Ito, K. and Akiyama, Y.
J. Biol. Chem.   283 35042-35052   2008   [Refereed]
Inaba K.*, Murakami S, Suzuki M, Nakagawa A, Yamashita E, Okada K, Ito K.*
Cell   127(4) 789-801   Nov 2006   [Refereed]
Takahashi YH, Inaba K, Ito K
Antioxidants & redox signaling   8(5-6) 743-752   May 2006   [Refereed]
Inaba K, Takahashi YH, Ito K, Hayashi S
Proceedings of the National Academy of Sciences of the United States of America   103(2) 287-292   Jan 2006   [Refereed]
Inaba K, Takahashi YH, Ito K
The Journal of biological chemistry   280(38) 33035-33044   Sep 2005   [Refereed]
Takahashi YH, Inaba K, Ito K
The Journal of biological chemistry   279(45) 47057-47065   Nov 2004   [Refereed]
Inaba K, Takahashi YH, Fujieda N, Kano K, Miyoshi H, Ito K
The Journal of biological chemistry   279(8) 6761-6768   Feb 2004   [Refereed]

Misc

 
奥村 正樹, 金村 進吾, 稲葉 謙次
日本生物物理学会誌   55 34-36   Dec 2014
哺乳動物細胞の小胞体におけるジスルフィド結合形成ネットワークの構造基盤
奥村 正樹, 稲葉 謙次
実験医学   30 208-215   Apr 2014
分泌タンパク質の成熟化を監視するpHに依存的な新たなタンパク質品質管理機構の発見
増井 翔史, Roberto Sitia, 稲葉 謙次
ライフサイエンス新着論文レビュー   7229    May 2013

Books etc

 
Structural insights into disulfide bond formation and protein quality control in the mammalian endoplasmic reticulum
Okumura, M., Watanabe, S. and Inaba, K. (Part:Contributor)
Royal Society of Chemistry   2018   

Conference Activities & Talks

 
Zinc ions have a new physiological role in protein quality control in the early secretory pathway [Invited]
INABA Kenji
CWRU-Tohoku joint symposium   Aug 2018   
Zinc ions regulate ERp44-mediated protein quality control in the early secretory pathway [Invited]
INABA Kenji
International Meeting “Proteins: from the cradle to the grave”   Aug 2018   
The highly dynamic nature of ERdj5 plays a key role in efficient ER-associated degradation of aberrant protein oligomers [Invited]
INABA Kenji
International Forum "Redpx Biology"   Mar 2018   
How do PDI family member proteins act on unfolded/misfolded proteins to ensure protein quality control in the ER? [Invited]
INABA Kenji
Nascent Chain Biology meeting   Aug 2016   
Dynamic natures of PDI family members in catalysis of oxidative protein folding and ER associated degradation [Invited]
INABA Kenji
EMBO meeting   Sep 2015   
Dynamic natures of PDI family members in catalysis of oxidative protein folding and ER associated degradation [Invited]
INABA Kenji
Case Western Reserve University-Tohoku University joint symposium   Jul 2015   
Dual conformations of ERdj5 play a significant role in acceleration of the ER associated degradation.
INABA Kenji
ER & Redox club meeting   Apr 2015   
The protein disulfide bond formation system in mammalian cells [Invited]
INABA Kenji
Kyushu-U and Stanford-U Joint Research and Education Program   Mar 2015   
Structural and mechanistic basis of the protein disulfide bond formation system in mammalian cells [Invited]
INABA Kenji
The 15th RIES-Hokudai International Symposium   Dec 2014   
Structural and mechanistic basis of the protein disulfide bond formation system in mammalian cells [Invited]
INABA Kenji
The 7th Korea-Japan Seminars on Biomolecular Sciences   Nov 2014   
Structural and mechanistic basis of protein disulfide bond formation network in mammalian cells [Invited]
INABA Kenji
17th Biennial Meeting of Society for Free Radical Research International   Mar 2014   
Structural and mechanistic basis of regulated and specific protein disulfide bond formation in human cells
INABA Kenji
Quality control; folding and degradation of proteins in the endoplasmic reticulum   Sep 2011   
Structure and mechanism of protein disulfide bond formation systems in human cells
INABA Kenji
ESF research conference; Glutathione and related thiols in living cells   Sep 2011   
Structural basis of regulated protein disulfide bond formation in human cells [Invited]
INABA Kenji
The 3rd international symposium on protein community   Sep 2010   
Crystal structures of mammalian human Ero1 and ERdj5, the enzymes involved in ER quality control [Invited]
INABA Kenji
Gordon Research Conference on thiol-based redox regulation & signaling   May 2010   
Structure and mechanism of the DsbB-DsbA protein disulfide generation system in E. coli [Invited]
INABA Kenji
XXI Congress and General Assembly of the International union of Crystallography   Aug 2008   
Structural basis for protein disulfide generation in the cell [Invited]
INABA Kenji
Gordon Research Conference on thiol-based redox regulation & signaling   May 2008   
Crystal structure of the DsbB-DsbA complex reveals a mechanism of protein disulfide bond generation in E. coli. [Invited]
INABA Kenji
2nd International Symposium on Diffraction structural Biology   Sep 2007   
Structural basis of the DsbA-DsbB-UQ oxidative system in E. coli. [Invited]
INABA Kenji
Boden Conference on disulfide bonds and their role in protein folding and function   Jul 2007   
How are protein disulfide bonds generated in the cell? [Invited]
INABA Kenji
International Symposium on Milestone of Life of Proteins, Kyoto   Mar 2007   
Crystal Structure of DsbB-DsbA Complex Revealing a Cysteine Relocation Mechanism [Invited]
INABA Kenji
Joint Conference of the Asian Crystallographic association and the Crystallographic Society of Japan   Nov 2006   
Crystal structure of the DsbB-DsbA complex revealing a cysteine relocation process for disulfide bond generation [Invited]
Inaba, K., Murakami, S., Suzuki, M., Nakagawa, A., Yamashita, E., Okada, K. and Ito, K.
Switzerland-Japan Symposium on Structural Biology 2006   Sep 2006   
Crystal Structure of DsbB-DsbA Complex Revealing a Cysteine Relocation Mechanism
INABA Kenji
Inaba K. and Ito K.   Jul 2006   

Research Grants & Projects

 
JST: PRESTO
Project Year: Dec 2001 - Mar 2005    Investigator(s): INABA Kenji