Ayana Kon

Profile Information

Affiliation: Kyoto University

Degree: 医学博士(東京大学)

J-GLOBAL ID: 201601004260315918
researchmap Member ID: 7000015375

External link: https://www.med.kyoto-u.ac.jp/organization-staff/research/doctoral_course/r-006/

Research Interests

Research Areas

Life sciences / Hematology and oncology /

Research History

Apr, 2023 - Present

Department of Pathology and Tumor Biology, Kyoto University, Graduate School of Medicine
Apr, 2018 - Mar, 2023

Graduate School of Medicine, Kyoto University
Apr, 2016 - Mar, 2018

Graduate School of Medicine, Kyoto University
Apr, 2015 - Mar, 2016

日本学術振興会特別研究員(PD)
Apr, 2014 - Mar, 2015

日本学術振興会特別研究員(DC2)
Apr, 2009 - Mar, 2011

内科レジデント, 国家公務員共済組合連合会虎の門病院
Apr, 2008 - Mar, 2009

研修医, 社会福祉法人三井記念病院
Apr, 2007 - Mar, 2008

研修医, 東京大学医学部付属病院

Education

Apr, 2011 - Mar, 2015

Graduate School of Medicine, The University of Tokyo
Apr, 2001 - Mar, 2007

School of Medicine, Faculty of Medicine, The University of Tokyo

Committee Memberships

Apr, 2023 - Present

環境管理専門委員会有機廃液情報管理小委員会全学委員, 京都大学
Apr, 2017 - Present

医学研究科動物実験施設運営委員会, 京都大学

Awards

Jul, 2023

第13回JSH国際シンポジウム Best Symposium Award, 日本血液学会
2018

日本癌学会奨励賞
2015

日本血液学会奨励賞
2015

ISEH 44th Annual Scientific Meeting Travel Grant Award
2015

20th Congress of EHA Travel Award
2013

AACR-Bristol-Myers Squibb Oncology Scholar-in-Training Award
2012

ASH Abstract Achievement Award
2012

17th Congress of EHA Travel Award

Papers

SETBP1 is dispensable for normal and malignant hematopoiesis.

Atsushi Tanaka, Koutarou Nishimura, Wataru Saika, Ayana Kon, Yui Koike, Hiromi Tatsumi, June Takeda, Masaki Nomura, Weijia Zang, Manabu Nakayama …

Leukemia, Jul 18, 2023
Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato …

Blood, 141(5) 534-549, Feb 2, 2023 Peer-reviewed
Amplified EPOR/JAK2 genes define a unique subtype of acute erythroid leukemia.

June Takeda, Kenichi Yoshida, Masahiro M Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi …

Blood cancer discovery, 3(5) 410-427, Jul 15, 2022 Peer-reviewed
A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells

Keita Yamamoto, Susumu Goyama, Shuhei Asada, Takeshi Fujino, Taishi Yonezawa, Naru Sato, Reina Takeda, Akiho Tsuchiya, Tomofusa Fukuyama, Yosuke Tanaka …

Cell Reports, 36(8) 109576-109576, Aug, 2021 Peer-reviewed
Clonal evolution of myeloid malignancies

Ayana Kon

[Rinsho ketsueki] The Japanese journal of clinical hematology, 61(9) 1120-1129, Sep, 2020 Peer-reviewedLead author
Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.

Yotaro Ochi, Ayana Kon, Toyonori Sakata, Masahiro M Nakagawa, Naotaka Nakazawa, Masanori Kakuta, Keisuke Kataoka, Haruhiko Koseki, Manabu Nakayama, Daisuke Morishita …

Cancer discovery, 10(6) 836-853, Jun, 2020 Peer-reviewed
[Clonal evolution of myelodysplastic syndromes].

Ayana Kon

[Rinsho ketsueki] The Japanese journal of clinical hematology, 61(4) 358-367, Apr, 2020 Peer-reviewed
Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.

Nobuyuki Kakiuchi, Kenichi Yoshida, Motoi Uchino, Takako Kihara, Kotaro Akaki, Yoshikage Inoue, Kenji Kawada, Satoshi Nagayama, Akira Yokoyama, Shuji Yamamoto …

Nature, 577(7789) 260-265, Jan, 2020 Peer-reviewed
Molecular pathogenesis of disease progression in MLL-rearranged AML.

Shinichi Kotani, Akinori Yoda, Ayana Kon, Keisuke Kataoka, Yotaro Ochi, Yusuke Shiozawa, Cassandra Hirsch, June Takeda, Hiroo Ueno, Tetsuichi Yoshizato …

Leukemia, 33(3) 612-624, Mar, 2019 Peer-reviewed
Myelodysplastic Syndrome-Associated SRSF2 Mutations Cause Splicing Changes by Altering Binding Motif Sequences.

So Masaki, Shun Ikeda, Asuka Hata, Yusuke Shiozawa, Ayana Kon, Seishi Ogawa, Kenji Suzuki, Fumihiko Hakuno, Shin-Ichiro Takahashi, Naoyuki Kataoka

Frontiers in genetics, 10 338-338, 2019 Peer-reviewed
ゲノム解析から見た赤白血病(Genomic characteristics of acute erythroid leukemia)

竹田淳恵, Shih Lee-Yung, 千葉健一, 白石友一, 塩澤裕介, 牧島秀樹, 吉里哲一, 永田安伸, 半下石明, 石山謙 …

臨床血液, 59(9) 1521-1521, Sep, 2018
A novel genetic and morphologic phenotype of ARID2-mediated myelodysplasia

H. Sakai, N. Hosono, H. Nakazawa, B. Przychodzen, C. Polprasert, H. E. Carraway, M. A. Sekeres, T. Radivoyevitch, K. Yoshida, M. Sanada …

Leukemia, 32(3) 839-843, Mar 1, 2018 Peer-reviewed
Physiological Srsf2 P95H expression causes impaired hematopoietic stem cell functions and aberrant RNA splicing in mice

Ayana Kon, Satoshi Yamazaki, Yasuhito Nannya, Keisuke Kataoka, Yasunori Ota, Masahiro Marshall Nakagawa, Kenichi Yoshida, Yusuke Shiozawa, Maiko Morita, Tetsuichi Yoshizato …

Blood, 131(6) 621-635, Feb 8, 2018 Peer-reviewed
Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia

Masafumi Seki, Shunsuke Kimura, Tomoya Isobe, Kenichi Yoshida, Hiroo Ueno, Yaeko Nakajima-Takagi, Changshan Wang, Lin Lin, Ayana Kon, Hiromichi Suzuki …

Nature Genetics, 49(8) 1274-1281, Aug 1, 2017 Peer-reviewed
Somatic PHF6 mutations in 1760 cases with various myeloid neoplasms

T. Mori, Y. Nagata, H. Makishima, M. Sanada, Y. Shiozawa, A. Kon, T. Yoshizato, A. Sato-Otsubo, K. Kataoka, Y. Shiraishi …

Leukemia, 30(11) 2270-2273, Nov 1, 2016 Peer-reviewed
Variegated RHOA mutations in adult T-cell leukemia/lymphoma

Yasunobu Nagata, Kenji Kontani, Terukazu Enami, Keisuke Kataoka, Ryohei Ishii, Yasushi Totoki, Tatsuki R. Kataoka, Masahiro Hirata, Kazuhiro Aoki, Kazumi Nakano …

BLOOD, 127(5) 596-604, Feb, 2016 Peer-reviewed
BRCC3 mutations in myeloid neoplasms

Dayong Huang, Yasunobu Nagata, Vera Grossmann, Tomas Radivoyevitch, Yusuke Okuno, Genta Nagae, Naoko Hosono, Susanne Schnittger, Masashi Sanada, Bartlomiej Przychodzen …

HAEMATOLOGICA, 100(8) 1051-1057, Aug, 2015 Peer-reviewed
Somatic Mutations and Clonal Hematopoiesis in Aplastic Anemia

T. Yoshizato, B. Dumitriu, K. Hosokawa, H. Makishima, K. Yoshida, D. Townsley, A. Sato-Otsubo, Y. Sato, D. Liu, H. Suzuki …

NEW ENGLAND JOURNAL OF MEDICINE, 373(1) 35-47, Jul, 2015 Peer-reviewed
骨髄系腫瘍541例におけるPHF6異常の解明

森拓人, 永田安伸, 吉田健一, 塩澤祐介, 吉里哲一, 昆彩奈, 佐藤亜以子, 白石友一, 千葉健一, 田中洋子 …

臨床血液, 55(9) 1296-1296, Sep, 2014
Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome

Yusuke Sato, Shigekatsu Maekawa, Ryohei Ishii, Masashi Sanada, Teppei Morikawa, Yuichi Shiraishi, Kenichi Yoshida, Yasunobu Nagata, Aiko Sato-Otsubo, Tetsuichi Yoshizato …

SCIENCE, 344(6186) 917-920, May, 2014 Peer-reviewed

Misc.

Splicing factor mutations in hematological malignancies

Ayana Kon

41(13), Aug, 2023 Peer-reviewedInvitedLead authorCorresponding author
【がんと慢性炎症】骨髄異形成症候群と慢性炎症

昆彩奈

別冊Bio Clinica: 慢性炎症と疾患, 11(2) 37-41, Nov, 2022
血液疾患におけるBCOR遺伝子変異の意義

昆彩奈

血液内科, 85(3) 384-389, Sep, 2022
骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明(Elucidating the mechanism of clonal evolution of DDX41 mutated cells in myeloid malignancies)

昆彩奈, 中川正宏, 片岡圭亮, 垣内伸之, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本癌学会総会記事, 81回 E-1066, Sep, 2022
Mis-splicing due to somatic U2AF2 mutations in myeloid neoplasms(和訳中)

Qi Xingxing, Yoshizatoi Tetuichi, 南谷泰仁, Nakagawa Masahiro M., 森拓人, 昆彩奈, 依田成玄, 越智陽太郎, 竹田淳恵, 佐伯龍之介 …

日本癌学会総会記事, 81回 P-1255, Sep, 2022
単一細胞マルチオミクス解析によるクローン性造血の病態解明(Distinct pathogenesis of clonal hematopoiesis revealed by single-cell multi-omics sequencing)

中川正宏, 稲垣良作, 南谷泰仁, 佐伯龍之介, 越智陽太郎, 竹田淳恵, 趙蘭英, 威星星, 依田成玄, 昆彩奈 …

日本癌学会総会記事, 81回 IS8-6, Sep, 2022
骨髄異形成症候群におけるSRSF2変異とSTAG2変異と協調的関係(Cooperative effects of SRSF2 and STAG2 mutations on development of myelodysplastic syndrome and its related disorders)

森拓人, 越智陽太郎, 昆彩奈, 吉里哲一, 古関明彦, 依田成玄, 中川正宏, 竹田淳恵, 永田安伸, 吉田健一 …

日本癌学会総会記事, 81回 IS11-6, Sep, 2022
Amplified EPOR/JAK2 genes definea unique subtype of acute erythroid leukemia.

June Takeda, Kenichi Yoshida, Masahiro M. Nakagawa, Yasuhito Nannya, Akinori Yoda, Ryunosuke Saiki, Yotaro Ochi, Lanying Zhao, Rurika Okuda, Xingxing Qi …

CANCER RESEARCH, 82(12), Jun, 2022
【赤血球系疾患診療の最近の進歩】MDSにおけるゲノム解析研究の進歩

昆彩奈

血液内科, 84(1) 65-71, Jan, 2022
Distinct pathogenesis of clonal hematopoiesis revealed by single-cell sequencing(和訳中)

中川正宏, 稲垣良作, 黒田隆, 南谷泰仁, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈 …

日本血液学会学術集会, 83回 OS1-3, Sep, 2021
ETNK1 mutations defines a subclass of der(1;7)(q10;p10) in myelodysplastic syndromes(和訳中)

奥田瑠璃花, 南谷泰人, 越智陽太郎, 蝶名林和久, 牧島秀樹, 吉里哲一, 永田安伸, 竹田淳恵, 吉田健一, 眞田昌 …

日本血液学会学術集会, 83回 OS1-4, Sep, 2021
The functional role of compound DDX41 germline and somatic R525H mutations in the development of myeloid neoplasms

Ayana Kon, Masahiro Nakagawa, Ryosaku Inagaki, Keisuke Kataoka, Yotaro Ochi, Hideki Makishima, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa

CANCER SCIENCE, 112 454-454, Feb, 2021
Early Clonal evolution of myeloid malignancies

Masahiro Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Xingxing Qi, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi …

CANCER SCIENCE, 112 969-969, Feb, 2021
Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes.

Rurika Okuda, Yasuhito Nannya, Yotaro Ochi, Kazuhisa Chonabayashi, Maria Creignou, Hideki Makishima, June Takeda, Ayana Kon, Satoru Miyano, Hiroshi Handa …

CANCER SCIENCE, 112 310-310, Feb, 2021
JAK STAT Pathway is a Promising Therapeutic target in Acute Erythroid Leukemia

June Takeda, Kenichi Yoshida, Akinori Yoda, Yasuhito Nannya, Masahiro Nakagawa, Yotaro Ochi, Ayana Kon, Tetsuichi Yoshizato, Yusuke Shiozawa, Yuichi Shiraishi …

CANCER SCIENCE, 112 453-453, Feb, 2021
The molecular pathogenesis of DDX41-mutated myeloid neoplasms

昆彩奈, 中川正宏, 片岡圭亮, 片岡圭亮, 稲垣良作, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁 …

日本血液学会学術集会抄録(Web), 83rd, 2021
骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明

昆彩奈, 中川正宏, 片岡圭亮, 片岡圭亮, 稲垣良作, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁 …

日本癌学会学術総会抄録集(Web), 80th, 2021
変異と発現のマルチオミクス単一細胞解析によって明らかにされたクローン造血における初期変異細胞の有する非細胞自律性作用

中川正宏, 稲垣良作, 南谷泰仁, 趙蘭英, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈 …

日本癌学会学術総会抄録集(Web), 80th, 2021
Functional Characterization of Compound DDX41 Germline and Somatic R525H Mutations in the Development of Myeloid Malignancies

Ayana Kon, Masahiro Marshall Nakagawa, Ryosaku Inagaki, Keisuke Kataoka, Hideki Makishima, Yotaro Ochi, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa

BLOOD, 136, Nov, 2020
Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Qi Xingxing, Akinori Yoda, Ayana Kon …

BLOOD, 136, Nov, 2020

Presentations

骨髄異形成症候群におけるSRSF2変異とSTAG2変異と協調的関係(Cooperative effects of SRSF2 and STAG2 mutations on development of myelodysplastic syndrome and its related disorders)

森拓人, 越智陽太郎, 昆彩奈, 吉里哲一, 古関明彦, 依田成玄, 中川正宏, 竹田淳恵, 永田安伸, 吉田健一, 眞田昌, 牧島秀樹, 高折晃史, 熱田由子, 南谷泰仁, 小川誠司

日本癌学会総会記事, Sep, 2022, (一社)日本癌学会
単一細胞マルチオミクス解析によるクローン性造血の病態解明(Distinct pathogenesis of clonal hematopoiesis revealed by single-cell multi-omics sequencing)

中川正宏, 稲垣良作, 南谷泰仁, 佐伯龍之介, 越智陽太郎, 竹田淳恵, 趙蘭英, 威星星, 依田成玄, 昆彩奈, 垣内伸之, 牧島秀樹, 松田秀一, 小川誠司

日本癌学会総会記事, Sep, 2022, (一社)日本癌学会
Mis-splicing due to somatic U2AF2 mutations in myeloid neoplasms(和訳中)

Qi Xingxing, Yoshizatoi Tetuichi, 南谷泰仁, Nakagawa Masahiro M., 森拓人, 昆彩奈, 依田成玄, 越智陽太郎, 竹田淳恵, 佐伯龍之介, Lanying Zhao, Haferlach Torsten, Kanemura Nobuhiro, Kasahara Senji, 牧島秀樹, 小川誠司

日本癌学会総会記事, Sep, 2022, (一社)日本癌学会
骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明(Elucidating the mechanism of clonal evolution of DDX41 mutated cells in myeloid malignancies)

昆彩奈, 中川正宏, 片岡圭亮, 垣内伸之, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本癌学会総会記事, Sep, 2022, (一社)日本癌学会
ETNK1 mutations defines a subclass of der(1;7)(q10;p10) in myelodysplastic syndromes(和訳中)

奥田瑠璃花, 南谷泰人, 越智陽太郎, 蝶名林和久, 牧島秀樹, 吉里哲一, 永田安伸, 竹田淳恵, 吉田健一, 眞田昌, 昆彩奈, 白石雄一, 宮野悟, 熱田由子, 笠原千嗣, 半田寛, 千葉滋, 大屋敷一馬, 吉田善紀, 小川誠司

日本血液学会学術集会, Sep, 2021, (一社)日本血液学会
Distinct pathogenesis of clonal hematopoiesis revealed by single-cell sequencing(和訳中)

中川正宏, 稲垣良作, 黒田隆, 南谷泰仁, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈, 吉里哲一, 垣内伸之, 牧島秀樹, 松田秀一, 小川誠司

日本血液学会学術集会, Sep, 2021, (一社)日本血液学会
The molecular pathogenesis of DDX41-mutated myeloid neoplasms(和訳中)

昆彩奈, 中川正宏, 片岡圭亮, 稲垣良作, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本血液学会学術集会, Sep, 2021, (一社)日本血液学会
骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明

昆彩奈, 中川正宏, 片岡圭亮, 稲垣良作, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本癌学会総会記事, Sep, 2021, (一社)日本癌学会
一細胞解像度のがん生物学変異と発現のマルチオミクス単一細胞解析によって明らかにされたクローン造血における初期変異細胞の有する非細胞自律性作用

中川正宏, 稲垣良作, 南谷泰仁, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈, 吉里哲一, 垣内伸之, 牧島秀樹, 松田秀一, 小川誠司

日本癌学会総会記事, Sep, 2021, (一社)日本癌学会
変異と発現のマルチオミクス単一細胞解析によって明らかにされたクローン造血における初期変異細胞の有する非細胞自律性作用

中川正宏, 稲垣良作, 南谷泰仁, 趙蘭英, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈, 吉里哲一, 垣内伸之, 牧島秀樹, 松田秀一, 小川誠司, 小川誠司, 小川誠司

日本癌学会学術総会抄録集(Web), 2021
骨髄系腫瘍におけるDDX41胚細胞変異・体細胞変異の分子病態の解明

昆彩奈, 中川正宏, 片岡圭亮, 片岡圭亮, 稲垣良作, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本癌学会学術総会抄録集(Web), 2021
The molecular pathogenesis of DDX41-mutated myeloid neoplasms

昆彩奈, 中川正宏, 片岡圭亮, 片岡圭亮, 稲垣良作, 牧島秀樹, 越智陽太郎, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本血液学会学術集会抄録(Web), 2021
Genotype-Phenotype Relationships and Therapeutic Targets in Acute Erythroid Leukemia

June Takeda, Kenichi Yoshida, Akinori Yoda, Lee-Yung Shih, Yasuhito Nannya, Yotaro Ochi, Ayana Kon, Kenichi Chiba, Yuichi Shiraishi, Yusuke Shiozawa, Tetsuichi Yoshizato, Cassandra M. Kerr, Yasunobu Nagata, Toshiyuki Kitano, Akira Hangaishi, Ken Ishiyama, Hisashi Tsurumi, Yasushi Miyazaki, Nobuhiro Hiramoto, Takayuki Ishikawa, Masahiro Marshall Nakagawa, Akifumi Takaori-Kondo, Shigeru Chiba, Hideyuki Nakazawa, Ming-Chung Kuo, Keisuke Kataoka, Ryunosuke Saiki, Hiroko Tanaka, Kensuke Usuki, Shuichi Miyawaki, Satoru Miyano, Jaroslaw P. Maciejewski, Arnold Ganser, Michael Heuser, Felicitas Thol, Hideki Makishima, Seishi Ogawa

BLOOD, Nov, 2020, AMER SOC HEMATOLOGY
Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Qi Xingxing, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda, Seishi Ogawa

BLOOD, Nov, 2020, AMER SOC HEMATOLOGY
Functional Characterization of Compound DDX41 Germline and Somatic R525H Mutations in the Development of Myeloid Malignancies

Ayana Kon, Masahiro Marshall Nakagawa, Ryosaku Inagaki, Keisuke Kataoka, Hideki Makishima, Yotaro Ochi, Manabu Nakayama, Haruhiko Koseki, Yasuhito Nannya, Seishi Ogawa

BLOOD, Nov, 2020, AMER SOC HEMATOLOGY
がんの一細胞生物学骨髄系腫瘍の早期クローン進展の解析

中川正宏, 稲垣良作, 南谷泰仁, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈, 垣内伸之, 牧島秀樹, 松田秀一, 小川誠司

日本癌学会総会記事, Oct, 2020, (一社)日本癌学会
骨髄異形成症候群における新規DDX41胚細胞変異・体細胞変異の機能解析

昆彩奈, 中川正宏, 稲垣良作, 片岡圭亮, 越智陽太郎, 牧島秀樹, 中山学, 古関明彦, 南谷泰仁, 小川誠司

日本癌学会総会記事, Oct, 2020, (一社)日本癌学会
急性赤白血病におけるJAK阻害剤の検討

竹田淳恵, 吉田健一, 依田成玄, 南谷泰仁, 中川正宏, 越智陽太郎, 昆彩奈, 吉里哲一, 塩澤裕介, 白石友一, 千葉健一, 田中洋子, 真田昌, 宮野悟, 牧島秀樹, 小川誠司

日本癌学会総会記事, Oct, 2020, (一社)日本癌学会
骨髄異形成症候群におけるder(1;7)の民族的、臨床的、遺伝的特徴(Distinct ethnic, clinical, and genetic characteristics of der(1;7) in myelodysplastic syndromes)

奥田瑠璃花, 南谷泰仁, 越智陽太郎, 蝶名林和久, Creignou Maria, 牧島秀樹, 竹田淳恵, 昆彩奈, 宮野悟, 半田寛, 千葉滋, 大屋敷一馬, Haferlach Torsten, Lindberg Eva, 小川誠司

日本癌学会総会記事, Oct, 2020, (一社)日本癌学会
がんの一細胞生物学骨髄系腫瘍の早期クローン進展の解析

中川正宏, 稲垣良作, 南谷泰仁, 趙蘭英, 越智陽太郎, 竹田淳恵, 戚星星, 依田成玄, 昆彩奈, 垣内伸之, 牧島秀樹, 松田秀一, 小川誠司

日本癌学会総会記事, Oct, 2020, (一社)日本癌学会

Teaching Experience

2016 - Present

Pathology (Kyoto University)

Professional Memberships

Research Projects

Elucidating the mechanisms of clonal evolution of myeloid neoplasms with germline predisposition

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
comprehensive studies on the molecular basis of early development and clonal evolution in cancer using advanced genomics.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (S), Japan Society for the Promotion of Science, Jun, 2019 - Mar, 2024
Elucidating the contribution of the order of mutation acquisition to the clonal evolution of cancer using single-cell sequencing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jul, 2020 - Mar, 2022

Ogawa Seishi
Elucidating the molecular mechanisms underlying the clonal evolution of leukemic stem cells

Grants-in-Aid for Scientific Research, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Kon Ayana
Computational reconstruction of the higher-order structure of chromosomes and linkage analysis between chromosome structure and phenotype

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2015 - Mar, 2020

Itoh Takehiko
Molecular pathogenesis of bone marrow failure elucidated by comprehensive sequencing.

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

MAKISHIMA HIDEKI, YOSHIDA Kenichi, KON Ayana, KATAOKA Keisuke, ONO Kinji, KOSEKI Haruhiko, Miyazaki Yasushi, Chiba Shigeru, Nakao Shinji
Biological characterization of DDX41 germline and somatic mutations in myeloid neoplasms

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2018

Kon Ayana, OGAWA Seishi, KOSEKI Haruhiko, NAKAYAMA Manabu
新規遺伝子変異標的ＳＦ３Ｂ１などによる骨髄異形成症候群の発症メカニズムの解明

科学研究費助成事業, 特別研究員奨励費, 日本学術振興会, Apr, 2014 - Mar, 2016

昆彩奈

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