謙次八木

Profile Information

Affiliation: Kawasaki Medical School

J-GLOBAL ID: 201601003530480456
researchmap Member ID: 7000015928

Research Areas

Life sciences / Neurosurgery /

Papers

Association between Carotid Bifurcation Angle and Vulnerable Plaque Volume Using Black Blood Magnetic Resonance Imaging

Hiroki TAKAI, Shunji MATSUBARA, Yukari MINAMI-OGAWA, Satoshi HIRAI, Eiji SHIKATA, Kenji YAGI, Naoki OYAMA, Yoshiki YAGITA, Masaaki UNO

Neurologia medico-chirurgica, 2023
Acute surgical treatment for stroke

80(最新臨床脳卒中学(第2 版)上増刊号1) 527-532, Jan 31, 2022 Invited
自然血栓化・閉塞する過程を造影 CTA で確認できた大型前交通動脈瘤の 1 例

砂田芳宏, 八木謙次, 松原俊二, 宇野昌明

脳卒中, 2022
Bow hunter’s syndrome caused by compression of extracranially originated posterior inferior cerebellar artery.

Enomoto N, Yagi K, Matsubara S, Uno M

Frontiers in Neurology, 12 1-3, Oct 25, 2021
Variations and management for patients with craniocervical junction arteriovenous fistulas: Comparison of dural, radicular, and epidural arteriovenous fistulas.

Matsubara S, Toi H, Takai H, Miyazaki Y, Kinoshita K, Sunada Y, Yamada S, Tao Y, Enomoto N, Ogawa Minami Y …

Surgical Neurology International, 12 1-11, Aug 17, 2021 Peer-reviewed
両側infraoptic course of anterior cerebral artery に多数の破格を伴った内頸動脈瘤の1 例

高井洋樹, 松原俊二, 木下景太, 宮崎裕子, 船橋卯, 南祐佳里, 平井聡, 原慶次郎, 八木謙次, 宇野昌明

脳卒中, 43(4) 354-359, Jul 25, 2021
Clinical Features of Cytotoxic Lesions of the Corpus Callosum Associated with Aneurysmal Subarachnoid Hemorrhage.

Toi H, Yagi K, Matsubara S, Hara K, Uno M

AJNR Am J Neuroradiology, 42 1046-1051, Jun 15, 2021 Peer-reviewed
Improvement of Hemifacial Spasm after Stent-assisted Coil Embolization for Ipsilateral Vertebral Artery Dissecting Aneurysm.

Miyazaki Y, Matsubara S, Ishihara M, Ogawa Minami Y, Kinoshita K, Takai H, Hirai S, Hara K, Yagi K, Uno M

MC Case Report Journal, 8 143-150, Jun 7, 2021
Effectiveness of transvenous aspiration thrombectomy for cerebral venous sinus thrombosis: A report of three cases. Journal of Neuroendovascular Therapy

Minami (Ogawa) Y, Matsubara S, Hirai S, Miyazakin Y, Takai H, Yagi K, Iwamoto T, Goda T, Oyama N, Yagita Y …

Journal of Neuroendovascular Therapy, 15 1-8, Jun 1, 2021
Postoperative recurrence of chronic subdural hematoma is more frequent in patients with blood type A

Hirai S, Yagi K, Hara K, Kanda E, Matsubara S, Uno M

Journal of neurosurgery, In press, Jun, 2021 Peer-reviewed
Comparison of Single and Dual Monitoring during Carotid Endarterectomy

Masaaki UNO, Kenji YAGI, Hiroyuki TAKAI, Naoki OYAMA, Yoshiki YAGITA, Keita HAZAMA, Hideki NAKATSUKA, Shunji MATSUBARA

Neurologia medico-chirurgica, 61(2) 124-133, Feb 15, 2021 Peer-reviewed
Combination therapy using prothrombin complex concentrate and vitamin K in anticoagulated patients with traumatic intracranial hemorrhage prevents progressive hemorrhagic injury: a historically controlled study.

Koyama Hiroshi, Yagi Kenji, Hara Keijiro, Matsubara Shunji, Tao Yoshifumi, Uno Masaaki

Neurologia medico-chirurgica, 61(1) 47-54, Jan 15, 2021 Peer-reviewed
Effectiveness of Transvenous Aspiration Thrombectomy for Cerebral Venous Sinus Thrombosis: A Report of Three Cases

Yukari Minami (Ogawa), Shunji Matsubara, Satoshi Hirai, Yuko Miyazaki, Hiroki Takai, Kenji Yagi, Takanori Iwamoto, Toshiaki Goda, Naoki Oyama, Yoshiki Yagita …

Journal of Neuroendovascular Therapy, 15(8) 546-553, 2021
Increased plasma plasmin-α2-plasmin inhibitor complex levels correlate with postoperative rebleeding after endoscopic surgery for spontaneous intracerebral hemorrhage.

Kenji Yagi, Yoshifumi Tao, Keijirou Hara, Eiichiro Kanda, Satoshi Hirai, Hiroki Takai, Keita Kinoshita, Yukari Mimani, Yuko Miyazaki, Naoki Oyama …

Acta neurochirurgica, 162(12) 3129-3136, Dec, 2020
Increased plasma plasmin-alpha2-plasmin inhibitor complex levels correlate with postoperative rebleeding after endoscopic surgery for spontaneous intracerebral hemorrhage.

Yagi Kenji, Tao Yoshifumi, Hara Keijirou, Kanda Eiichiro, Hirai Satoshi, Takai Hiroki, Kinoshita Keita, Mimani Yukari, Miyazaki Yuko, Oyama Naoki …

Acta neurochirurgica, 162(12) 3129-3136, Nov 28, 2020 Peer-reviewed
Cardiogenic cerebral embolism caused by a severe hypoglycemic attack: a case report.

Koyama Hiroshi, Fujiwara Mika, Okita Shinya, Shirakawa Norihito, Yamada Hirotsugu, Ito Hiroyuki, Takagi Yasushi, Uno Masaaki, Yagi Kenji, Matsubara Syunji …

The Journal of Medical Investigation, 67(3.4) 362-364, Nov 5, 2020
Surgical technique of carotid endarterectomy: current methods and problems.

Uno Masaaki, Takai Hiroki, Yagi Kenji, Matsubara Shunji

Neurologia medico-chirurgica, 60(9) 419-428, Sep 15, 2020
Spontaneous improvement of secondary empty sella syndrome due to re-expansion of an intrasellar cyst: a case report.

Yamada Shodai, Yagi Kenji, Hirano Kazuhiro, Uno Masaaki

Surgical Neurology International, 11(282) 1-4, Sep 12, 2020
Markedly improved function in severe Hirayama disease by anterior cervical fusion: a case report.

Yagi Kenji, Kinoshita Keita, Hara Keijiro, Matsubara Shunji, Uno Masaaki

Interdisciplinary Neurosurgery, 21 1-4, Sep 1, 2020
Diagnosis and Operative Management of Carotid Endarterectomy in Patients with Twisted Carotid Bifurcation

Masaaki UNO, Kenji YAGI, Hiroyuki TAKAI, Keijiro HARA, Naoki OYAMA, Yoshiki YAGITA, Shunji MATSUBARA

Neurologia medico-chirurgica, 60(8) 383-389, Aug 15, 2020 Peer-reviewed

Books and Other Publications

Brain Nursing

(Role: Joint author)

Jun, 2019
原因別、病型別の再発予防-脳出血-「脳卒中後の管理と再発・重症化予防」

八木謙次, 宇野昌明 (Role: Joint author)

日本医事新報社, Mar, 2019
第12脳神経「後頭蓋窩の開頭とCEAとに必要な解剖」「第32回日本微小脳神経外科解剖研究会講演集」

八木謙次, 宇野昌明 (Role: Joint author)

メデット, 2018
術後管理の基本「パーフェクトマスター頸動脈狭窄症」

八木謙次, 里見淳一郎 (Role: Joint author)

メジカルビュー社, Apr, 2017
最新のエビデンス（外科系） STICH「分子脳血管病」

八木謙次, 永廣信治 (Role: Joint author)

先端医学社, 2006

Presentations

破裂動脈瘤クリッピングにおける術中未破裂動脈瘤化の前処置

八木謙次, 宇野昌明

第51回脳卒中の外学会学術集会, Mar 17, 2022
CEAの役割と課題、そして展望

宇野昌明, 高井洋樹, 八木謙次, 榎本紀哉, 南祐佳里, 田尾良文, 山田翔大, 砂田芳宏, 平井聡, 松原俊二

日本脳神経外科学会第80回学術総会, Oct 28, 2021
Craniocervical junction arteriovenous fistula: variations and management.

Oct 27, 2021
整容を意識した前頭-側頭開頭術

八木謙次, 宇野昌明

第80回日本脳神経外科学会総会, Oct 27, 2021
The greater the bifurcation angle between the common and internal carotid arteries, the higher the rate of vulnerable plaque volume.

Mar 11, 2021
血液型A型の慢性硬膜下血腫患者は術後再発が多い

平井聡, 山田翔大, 田尾良文, 榎本紀哉, 高井洋樹, 八木謙次, 松原俊二, 宇野昌明

第44回日本脳神経外傷学会, Feb 26, 2021
Two cases of middle cranial base osseous AVF.

Nov 19, 2020
A case of internal carotid aneurysm with multiple variations in the bilateral infraoptic course of ACAs.

Nov 19, 2020
前方固定が有効であった進行した平山病の一例

八木謙次, 木下景太, 宇野昌明

第35回日本脊髄外科学会, Nov 9, 2020
The greater the bifurcation angle between the common and internal carotid arteries, the higher the rate of vulnerable plaque volume.

Oct 15, 2020
Thrombectomy for ICA terminus, M1 proximal and M1 distal artery occlusion

Aug 23, 2020
高齢者の頸椎・頚髄疾患

八木謙次, 宇野昌明

第33回日本老年脳神経外科学会, Jul 15, 2020
難治性慢性硬膜下血腫に対する中硬膜動脈塞栓術後に再発した症例

宮崎裕子, 松原俊二, 高井洋樹, 南祐佳里, 木下景太, 平井聡, 原慶次郎, 八木謙次, 宇野昌明

第35回NPO法人日本脳神経血管内治療学会学術総会, Nov 21, 2019
Endovascular treatment for the patients with IC/MC tandem occlusion -antegrade approach or retrograde approach?-

The 35th Annual Meeting of The Japanese Society for Neuroendovascular Therapy, Nov 21, 2019
Twisted Carotid Bifurcation症例に対するCEA -診断と手術方法

宇野昌明, 八木謙次, 高井洋樹

日本脳神経外科学会第78回学術総会, Oct 11, 2019, 宮本享
慢性硬膜下血腫再発と ABO 血液型との関連

平井聡, 小川祐佳里, 木下景太, 高井洋樹, 宮崎裕子, 原慶次郎, 八木謙次, 松原俊二, 宇野昌明

日本脳神経外科学会第７８回学術総会, Oct 10, 2019
M1近位部閉塞に対する血栓回収療法ーIC先端部、 M1遠位部閉塞との相違点

松原俊二, 合田敏章, 岩本高典, 高井洋樹, 小川祐佳里, 木下景太, 平井聡, 宮崎裕子, 原慶次郎, 八木謙次, 谷本慧太, 大山直紀, 宇野昌明, 八木田佳樹

日本脳神経外科学会第78回学術総会, Oct 10, 2019
Hematomasa increases in chronic subdural hematomas with intracranial hypotension syndrome temporarily if epidural blood patch is performed previously.

The 78th Annual Meeting of the Japan Neurosurgical Society, Oct 10, 2019
慢性硬膜下血腫患者の術前の認知機能低下と予後の関連

原慶次郎, 小川祐佳里, 木下景太, 高井洋樹, 平井聡, 宮崎裕子, 八木謙次, 松原俊二, 宇野昌明

日本脳神経外科学会第78回学術総会, Oct 10, 2019
解離性椎骨動脈瘤に対するステントアシスト下コイル塞栓術後に治癒した片側顔面痙攣の一例

宮崎裕子, 松原俊二, 石原学, 南祐佳里, 高井洋樹, 平井聡, 原慶次郎, 八木謙次, 宇野昌明

第28回NPO法人日本脳神経血管内治療学会中国四国地方会, Sep 7, 2019

Research Projects

脳動脈瘤破裂におけるinflammasome活性化とsirtuinの役割

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

兼松康久, 高木康志, 八木謙次, 多田恵曜, 島田健司, 高麗雅章, 宮本健志, 四方英二
歯周病巣のexosomeによる脳動脈瘤破裂への影響

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

島田健司, 高木康志, 兼松康久, 八木謙次, 多田恵曜, 高麗雅章, 宮本健志, 四方英二, 山口泉
脳梗塞後PPARγ賦活による脳保護作用と神経再生

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2017 - Mar, 2020

木内智也, 多田恵曜, 高麗雅章, 八木謙次, 兼松康久
Intracranial aneurysms related to periodontal disease in basic- and clinical studies

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

KANEMATSU Yasuhisa
Early diagnosis and pharmacological treatment to prevent the rupture of cerebral aneurysms

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

NAGAHIRO Shinji
脳梗塞発症後のマクロファージ活性化とその制御による脳保護作用

科学研究費補助金 (基盤研究C), 文部科学省, Apr, 2015 - Mar, 2018
Bidirectional effects of statins on the formation and growth of cerebral aneurysms

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2009 - 2011

SATOMI Junichiro, NAGAHIRO Shinji, KANEMATSU Yasuhisa, YAGI Kenji, TADA Yoshiteru, SATA Masataka
molecular mechanisms in the formation and rupture of cerebral aneurysm and impact of drug treatment

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2009 - 2010

NAGAHIRO Shinji, SATA Masataka, SATOMI Junichiro, KANEMATSU Yasuhisa, YAGI Kenji, TADA Yoshiteru
Reductionof endothelial tight junction proteins on experimental cerebral aneurysm in rats

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2008 - 2010

NISHI Kyoko, NAGAHIRO Shinji, KANEMATSU Yasuhisa, UNO Masaaki, MATSUBARA Shunji, YAGI KENJI, TADA Yoshiteru

Industrial Property Rights

第5263548 イブジラストを有効成分とする脳動脈瘤の予防、形成抑制又は治療剤

永廣信治, 八木謙次, 北里慶子, 下河辺尚史

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