論文

査読有り
2020年5月1日

Anti-LRP4 Antibody-associated Myasthenia Gravis with a Rare Complication of Thymoma Successfully Treated by Thymectomy.

Internal medicine (Tokyo, Japan)
  • Sho Aoki
  • Kazuaki Nagashima
  • Minori Furuta
  • Kouki Makioka
  • Yukio Fujita
  • Kazuma Saito
  • Tomoyuki Kashima
  • Nozomi Nakajima
  • Hayato Ikota
  • Osamu Higuchi
  • Yoshio Ikeda
  • 全て表示

59
9
開始ページ
1219
終了ページ
1222
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2169/internalmedicine.3828-19

We herein report the case of a 65-year-old woman diagnosed with myasthenia gravis (MG) after complaining of double vision. The patient had anti-low-density lipoprotein receptor-related protein 4 (LRP4) antibody in her serum, although antibodies against the acetylcholine receptor and muscle-specific tyrosine kinase were not detected. Chest computed tomography showed an anterior mediastinal tumor with a high uptake on fluorodeoxyglucose-positron emission tomography. Endoscopic thymectomy successfully ameliorated her ocular symptoms and showed the lesion to be thymoma. The present case revealed that anti-LRP4 antibody-associated MG can be associated with thymoma, which has been regarded as a rare complication of this disease thus far.

リンク情報
DOI
https://doi.org/10.2169/internalmedicine.3828-19
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32051380
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270769
ID情報
  • DOI : 10.2169/internalmedicine.3828-19
  • PubMed ID : 32051380
  • PubMed Central 記事ID : PMC7270769

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