FUJITA MIKAKO

J-GLOBAL         Last updated: Dec 24, 2019 at 09:51
 
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Name
FUJITA MIKAKO
Affiliation
Kumamoto University
Section
Research Institute for Drug Discovery

Research Areas

 
 

Published Papers

 
Halil I. Ciftci, Raymond G. Sierra, Chun Hong Yoon, Zhen Su, Hiroshi Tateishi, Ryoko Koga, Koiwai Kotaro, Fumiaki Yumoto, Toshiya Senda, Mengling Liang, Soichi Wakatsuki, Masami Otsuka, Mikako Fujita, Hasan Demirci
International Journal of Molecular Sciences   20(7)    Apr 2019   [Refereed]
© 2019 by the authors. Licensee MDPI, Basel, Switzerland. The Human immunodeficiency virus-1 (HIV-1) matrix (MA) domain is involved in the highly regulated assembly process of the virus particles that occur at the host cell’s plasma membrane. High...
Ciftci HI, Bayrak N, Yıldırım H, Yıldız M, Radwan MO, Otsuka M, Fujita M, Tuyun AF
Archiv der Pharmazie   352(12) e1900170   Dec 2019   [Refereed]
Sever B, Altıntop MD, Radwan MO, Özdemir A, Otsuka M, Fujita M, Ciftci HI
European journal of medicinal chemistry   182 111648   Nov 2019   [Refereed]
Masunaga T, Murao N, Tateishi H, Koga R, Ohsugi T, Otsuka M, Fujita M
Bioorganic chemistry   92 103240   Nov 2019   [Refereed]
Mohamed O. Radwan, Ryoko Koga, Tomohiro Hida, Tomohiko Ejima, Yosuke Kanemaru, Hiroshi Tateishi, Yoshinari Okamoto, Jun ichiro Inoue, Mikako Fujita, Masami Otsuka
Bioorganic and Medicinal Chemistry Letters   29(16) 2162-2167   Jan 2019   [Refereed]
© 2019 Elsevier Ltd Zinc fingers have rarely been regarded as drug targets. On the contrary, the zinc-binding site of enzymes has often been considered a target of inhibitors. We previously developed a dithiol compound called SN-1 that binds to th...
Bayrak N, Yıldırım H, Yıldız M, Radwan MO, Otsuka M, Fujita M, Tuyun AF, Ciftci HI
Bioorganic chemistry   92 103255   Nov 2019   [Refereed]
Bayrak N, Yıldırım H, Yıldız M, Radwan MO, Otsuka M, Fujita M, Ciftci HI, Tuyun AF
Chemical biology & drug design      Nov 2019   [Refereed]
Shida W, Tateishi H, Tahara Y, Fujita M, Husham Majeed Alsaadi D, Watanabe M, Koga R, Radwan MO, Ciftci HI, Gezici S, Kurauchi Y, Katsuki H, Otsuka M, Sugimura K, Wada M, Sekeroglu N, Watanabe T
Molecules (Basel, Switzerland)   24(21)    Oct 2019   [Refereed]
Radwan MO, Ciftci HI, Ali TFS, Ellakwa DE, Koga R, Tateishi H, Nakata A, Ito A, Yoshida M, Okamoto Y, Fujita M, Otsuka M
Molecules (Basel, Switzerland)   24(18)    Sep 2019   [Refereed]
I Ciftci H, O Radwan M, E Ozturk S, Ulusoy NG, Sozer E, E Ellakwa D, Ocak Z, Can M, F S Ali T, I Abd-Alla H, Yayli N, Tateishi H, Otsuka M, Fujita M
Molecules (Basel, Switzerland)   24(19)    Sep 2019   [Refereed]
Ali TFS, Ciftci HI, Radwan MO, Koga R, Ohsugi T, Okiyama Y, Honma T, Nakata A, Ito A, Yoshida M, Fujita M, Otsuka M
Bioorganic & medicinal chemistry      Mar 2019   [Refereed]
Noguchi K, Ali TFS, Miyoshi J, Orito K, Negoto T, Biswas T, Taira N, Koga R, Okamoto Y, Fujita M, Otsuka M, Morioka M
European journal of medicinal chemistry   163 207-214   Feb 2019   [Refereed]
Ciftci HI, Ozturk SE, Ali TFS, Radwan MO, Tateishi H, Koga R, Ocak Z, Can M, Otsuka M, Fujita M
Biological & pharmaceutical bulletin   41(4) 570-574   Apr 2018   [Refereed]
Luong VH, Chino T, Oyama N, Matsushita T, Sasaki Y, Ogura D, Niwa SI, Biswas T, Hamasaki A, Fujita M, Okamoto Y, Otsuka M, Ihn H, Hasegawa M
Arthritis research & therapy   20(1) 46   Mar 2018   [Refereed]
Koga R, Yamamoto M, Ciftci HI, Otsuka M, Fujita M
FEBS open bio   8(1) 146-153   Jan 2018   [Refereed]
Koga R, Radwan MO, Ejima T, Kanemaru Y, Tateishi H, Ali TFS, Ciftci HI, Shibata Y, Taguchi Y, Inoue JI, Otsuka M, Fujita M
ChemMedChem   12(23) 1935-1941   Dec 2017   [Refereed]
Altıntop MD, Ciftci HI, Radwan MO, Sever B, Kaplancıklı ZA, Ali TFS, Koga R, Fujita M, Otsuka M, Özdemir A
Molecules (Basel, Switzerland)   23(1)    Dec 2017   [Refereed]
Tanaka A, Radwan MO, Hamasaki A, Ejima A, Obata E, Koga R, Tateishi H, Okamoto Y, Fujita M, Nakao M, Umezawa K, Tamanoi F, Otsuka M
Bioorganic & medicinal chemistry letters   27(16) 3862-3866   Aug 2017   [Refereed]
Tateishi H, Monde K, Anraku K, Koga R, Hayashi Y, Ciftci HI, DeMirci H, Higashi T, Motoyama K, Arima H, Otsuka M, Fujita M
Scientific reports   7(1) 8957   Aug 2017   [Refereed]
Yamamoto M, Koga R, Fujino H, Shimagaki K, Ciftci HI, Kamo M, Tateishi H, Otsuka M, Fujita M
The Journal of general virology   98(2) 275-283   Feb 2017   [Refereed]
Nilufer Bayrak, Hatice Yildirim, Amaç Fatih Tuyun, Emel Mataraci Kara, Berna Ozbek Celik, Girish Kumar Gupta, Halil I. Ciftci, Mikako Fujita, Masami Otsuka, Hamid R. Nasiri
Letters in Drug Design and Discovery   14 647-661   Jan 2017
© 2017 Bentham Science Publishers. Background: A set of novel sulfanyl aminonaphthoquinone derivatives (5a-j) were synthesized starting from 2,3-dichloro-1,4-naphthoquinone (1). The amine substituents were introduced via a nucleophilic substitutio...
Mohamed O. Radwan, Sachiko Sonoda, Tomohiko Ejima, Ayumi Tanaka, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
Bioorganic and Medicinal Chemistry   24 4398-4405   Sep 2016
© 2016 Elsevier LtdApolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G (APOBEC3G, A3G), is a human anti-virus restriction protein which works deaminase-dependently and -independently. A3G is known to be ubiquitinated by HIV-1 viral...
Masahiro Kamo, Hiroshi Tateishi, Ryoko Koga, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
Bioorganic and Medicinal Chemistry Letters   26 43-45   Jan 2016
© 2015 Elsevier Ltd.BMMP [2-(benzothiazol-2-ylmethylthio)-4-methylpyrimidine], an inhibitor of HIV-1 replication, was linked to biotin to study the interaction with the presumed target, HIV-1 Pr55Gag or CA, by means of surface plasmon resonance. T...
Muhammed Karabacak, Mehlika Dilek Altintop, Halil Ibrahim Çiftçi, Ryoko Koga, Masami Otsuka, Mikako Fujita, Ahmet Özdemir
Molecules   20 19066-19084   Oct 2015
© 2015 by the authors; licensee MDPI, Basel, Switzerland.New pyrazoline derivatives were synthesized and evaluated for their cytotoxic effects on AsPC-1 human pancreatic adenocarcinoma, U87 and U251 human glioblastoma cell lines. 1-[((5-(4-Methylp...
Taha F S Ali, Kana Iwamaru, Halil Ibrahim Ciftci, Ryoko Koga, Masahiro Matsumoto, Yasunori Oba, Hiromasa Kurosaki, Mikako Fujita, Yoshinari Okamoto, Kazuo Umezawa, Mitsuyoshi Nakao, Takuichiro Hide, Keishi Makino, Jun Ichi Kuratsu, Mohamed Abdel-Aziz, Gamal El Din A A Abuo-Rahma, Eman A M Beshr, Eman A M Beshr, Masami Otsuka
Bioorganic and Medicinal Chemistry   23 5476-5482   Sep 2015
© 2015 Elsevier Ltd.Previously we have reported a metal chelating histidine-pyridine-histidine system possessing a trityl group on the histidine imidazole, namely HPH-2Trt, which induces apoptosis in human pancreatic adenocarcinoma AsPC-1 cells. H...
Satomi Ida, Kana Iwamaru, Mikako Fujita, Yoshinari Okamoto, Yuri Kudo, Hiromasa Kurosaki, Masami Otsuka
Bioorganic Chemistry   62 8-14   Jul 2015
© 2015 Elsevier Inc.Abstract A tetrapeptide, l-histidyl-glycyl-glycyl-l-histidine (HGGH), was synthesized and the pUC19 plasmid DNA cleaving activity by copper(II) complex of HGGH (Cu(II)-HGGH) was investigated. Cu(II)-HGGH showed bleomycin-like D...
Halil Ibrahim Ciftci, Haruna Fujino, Ryoko Koga, Minami Yamamoto, Sogo Kawamura, Hiroshi Tateishi, Yasumasa Iwatani, Masami Otsuka, Mikako Fujita
FEBS Letters   589 1505-1514   Feb 2015
© 2015 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.In this study, we performed a mutational analysis to determine whether the mechanism by which HIV-2 Vpx confers the capacity for infectivity and vi...
Hiroshi Tateishi, Kensaku Anraku, Ryoko Koga, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
Organic and Biomolecular Chemistry   12 5006-5022   Jul 2014
The precursor of Gag protein (Pr55Gag) of human immunodeficiency virus, the principal structural component required for virus assembly, is known to bind d-myo-phosphatidylinositol 4,5-bisphosphate (PIP2). The N-terminus of Pr55Gag, the MA domain, ...
Ariko Miyake, Mikako Fujita, Haruna Fujino, Ryoko Koga, Sogo Kawamura, Masami Otsuka, Hirotaka Ode, Hirotaka Ode, Yasumasa Iwatani, Yosuke Sakai, Naoya Doi, Naoya Doi, Masako Nomaguchi, Akio Adachi, Yasuyuki Miyazaki
Journal of General Virology   95 179-189   Jan 2014
Human immunodeficiency virus type 2 (HIV-2) carries an accessory protein Vpx that is important for viral replication in natural target cells. In its C-terminal region, there is a highly conserved poly-proline motif (PPM) consisting of seven consec...
Ariko Miyake, Yasuyuki Miyazaki, Mikako Fujita, Masako Nomaguchi, Akio Adachi
Frontiers in Microbiology   5    Jan 2014
藤田美歌子
薬学雑誌   133(10) 1103-1111 (J-STAGE)-1111   Jan 2013
Human immunodeficiency virus (HIV) has no more than nine genes expressing approximately twenty proteins. When T lymphocytes and macrophages in a body are infected with HIV, these proteins work in turn at specific time and location, causing acquire...
Mikako Fujita, Masako Nomaguchi, Akio Adachi, Masami Otsuka
Frontiers in Microbiology   3    Jan 2012
Both human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) encode a unique set of accessory proteins that enhance viral replication in the host. Two similar accessory proteins, Vpx and Vpr, are encoded by HIV-2. In contrast, H...
Yasuyuki Miyazaki, Mikako Fujita
Frontiers in Microbiology   3    Jan 2012
Masako Nomaguchi, Mikako Fujita, Yasuyuki Miyazaki, Akio Adachi
Frontiers in Microbiology   3    Jan 2012
Yasuyuki Miyazaki, Mikako Fujita, Masako Nomaguchi, Akio Adachi
Frontiers in Microbiology   3    Jan 2012
Yosuke Kanemaru, Yumi Momiki, Saori Matsuura, Tatsufumi Horikawa, Jin Gohda, Jun Ichiro Inoue, Yoshinari Okamoto, Mikako Fujita, Masami Otsuka
Chemical and Pharmaceutical Bulletin   59 1555-1558   Dec 2011
Nuclear factor-κB (NF-κB) is an inducible transcription factor activated by a variety of cytokines, and promotes the transcription of genes involved in cancer, inflammation, autoimmune disease, and viral infection, among others. Because of its inv...
Tomohiko Ejima, Mayuko Hirota, Tamio Mizukami, Masami Otsuka, Mikako Fujita
International Journal of Molecular Medicine   28 613-616   Oct 2011
Human apoplipoprotein B mRNA-editing enzyme-catalytic polypeptide-like (APOBEC) 3G (A3G) is an antiviral protein that blocks HIV-1 replication. However, the antiviral activity of A3G is overcome by the HIV-1 protein Vif. This inhibitory function o...
Hideki Fujii, Hideki Fujii, Manabu Ato, Yoshimasa Takahashi, Kaori Otake, Shu ichi Hashimoto, Tomohiro Kaji, Yasuko Tsunetsugu-yokota, Mikako Fujita, Akio Adachi, Toshinori Nakayama, Masaru Taniguchi, Shigeo Koyasu, Toshitada Takemori, Toshitada Takemori
International Immunology   23 433-441   Jul 2011
The viral protein Nef is a key element for the progression of HIV disease. Previous in vitro studies suggested that Nef expression in T-cell lines enhanced TCR signaling pathways upon stimulation with TCR cross-linking, leading to the proposal tha...
Masako Nomaguchi, Mikako Fujita, Akio Adachi
Frontiers in Microbiology   2    Jan 2011
Kensaku Anraku, Ryota Fukuda, Nobutoki Takamune, Shogo Misumi, Yoshinari Okamoto, Masami Otsuka, Mikako Fujita
Biochemistry   49 5109-5116   Jun 2010
Human immunodeficiency virus type 1 (HIV-1) Gag protein is the principal structural component f the HIV particle. Localization of the Pr55Gag protein to the plasma membrane initiates virus assembly. Recent studies indicated that d-myo-phosphatidyl...
Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi
Reviews in Medical Virology   20 68-76   Mar 2010
Primate immunodeficiency viruses encode viral proteins that are uniquely auxiliary to their growth in host cells. Of these accessory proteins, those designated Vpr and Vpx are least well understood with respect to their functions in the viral repl...
Abhay Jere, Mikako Fujita, Akio Adachi, Masako Nomaguchi
Microbes and Infection   12 65-70   Jan 2010
The Nef protein of primate lentiviruses (simian and human immunodeficiency viruses; SIV/HIVs) appears to be multi-functional and plays a pivotal role in viral persistence and pathogenesis in vivo. Of its numerous functions reported to date, the ab...
Masako Nomaguchi, Naoya Doi, Sachi Fujiwara, Mikako Fujita, Akio Adachi
Frontiers in Microbiology   1    Jan 2010
HIV-1 Vpu acts positively on viral infectivity by mediating CD4 degradation in endoplasmic reticulum and enhances virion release by counteracting a virion release restriction factor, tetherin. In order to define the impact of Vpu activity on HIV-1...
Mikako Fujita, Masami Otsuka, Masako Nomaguchi, Akio Adachi
Microbes and Infection   10 1387-1392   Oct 2008
To determine functional regions of HIV-2 Vpx, we analyzed a series of site-specific vpx-mutants for their growth potentials in lymphocytic cells and compared the results with those in macrophages. We found that amino acid residues important for vi...
Mikako Fujita, Masami Otsuka, Masami Miyoshi, Boonruang Khamsri, Masako Nomaguchi, Akio Adachi, Akio Adachi
Journal of Virology   82 7752-7756   Aug 2008
The abilities of wild-type and vpx-defective human immunodeficiency virus type 2 (HIV-2) clones to synthesize viral DNA in human monocyte-derived macrophages (MDMs) and lymphocytic cells were comparatively and quantitatively evaluated. While the v...
Masako Nomaguchi, Mikako Fujita, Akio Adachi
Microbes and Infection   10 960-967   Jul 2008
Vpu is an accessory viral protein almost unique to HIV-1 among primate immunodeficiency viruses, and has two major functions: degradation of the CD4 molecule in endoplasmic reticulum and enhancement of virion release from cells. Recent identificat...
Ahmad Piroozmand, Ahmad Piroozmand, Yoshihiko Yamamoto, Boonruang Khamsri, Mikako Fujita, Tsuneo Uchiyama, Akio Adachi, Akio Adachi
Journal of Medical Investigation   54 154-158   Feb 2007
We have established a number of 293T cell lines that express a human anti HIV-1 factor APOBEC3G. Out of seven cell clones examined, four were readily demonstrated to express APOBEC3G by immunoblotting analysis. In particular, two clones (A3G-C1 an...
Kazuya Kamada, Tatsuhiko Igarashi, Malcolm A. Martin, Malcolm A. Martin, Boonruang Khamsri, Kazuki Hatcho, Tomoki Yamashita, Mikako Fujita, Tsuneo Uchiyama, Akio Adachi
Proceedings of the National Academy of Sciences of the United States of America   103 16959-16964   Nov 2006
The narrow host range of human immunodeficiency virus type 1 (HIV-1) is caused in part by innate cellular factors such as apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) and TRIM5α, which restrict virus replication in...
Boonruang Khamsri, Boonruang Khamsri, Mikako Fujita, Kazuya Kamada, Ahmad Piroozmand, Tomoki Yamashita, Tsuneo Uchiyama, Akio Adachi
International Journal of Molecular Medicine   18 679-683   Oct 2006
We previously demonstrated that the expression in cells of human immunodeficiency virus type 1 (HIV-1) Vif is maintained at low level by proteasome-degradation. We examined the contribution of 16 lysines present in Vif (NL432 clone), which is comp...
Ahmad Piroozmand, Boonruang Khamsri, Mikako Fujita, Akio Adachi, Tsuneo Uchiyama, Tsuneo Uchiyama
Journal of Medical Investigation   53 271-276   Aug 2006
We have previously shown that human immunodeficiency virus type 2 (HIV-2) without functional vpx and vpr genes is severely defective for viral growth in lymphocytic cells, and suggested that the virions produced in the absence of Vpx and Vpr are c...
Kazuya Kamada, Akiko Yoshida, Boonruang Khamsri, Ahmad Piroozmand, Tomoki Yamashita, Tsuneo Uchiyama, Mikako Fujita, Akio Adachi
Microbes and Infection   8 1075-1081   Apr 2006
Forty-nine recombinant viral clones between human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus from the rhesus monkey (SIVmac), which carry chimeric gag (capsid/p2 region) genes in the background of the HIV-1 genome, wer...
Boonruang Khamsri, Fumiko Murao, Akiko Yoshida, Akiko Sakurai, Tsuneo Uchiyama, Hiroki Shirai, Hiroki Shirai, Yo Matsuo, Mikako Fujita, Akio Adachi
Microbes and Infection   8 10-15   Jan 2006
The three-dimensional (3-D) structure of human immunodeficiency virus type 2 (HIV-2) Vpr/Vpx was predicted by homology modeling based on the NMR structure of human immunodeficiency virus type 1 (HIV-1) Vpr. The three proteins similarly have three ...
Miho Katoh, Miho Katoh, Kosuke Dodo, Kosuke Dodo, Mikako Fujita, Mikiko Sodeoka, Mikiko Sodeoka, Mikiko Sodeoka
Bioorganic and Medicinal Chemistry Letters   15 3109-3113   Jun 2005
A series of N-methyl-bisindolylmaleimide derivatives was synthesized and evaluated as cell death inhibitors. N-Methyl-2-[1-(3-aminopropyl)-1H-indol-3-yl] -3-(1H-indol-3-yl)maleimide (21) was the most potent inhibitor of H 2O2-induced necrotic deat...
Akiko Yoshida, Ahmad Piroozmand, Akiko Sakurai, Mikako Fujita, Tsuneo Uchiyama, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso, Akio Adachi
Microbes and Infection   7 820-824   May 2005
In order to obtain indicator cell lines that are exquisitely susceptible to human T-lymphotropic virus type 1 (HTLV-1), luciferase gene driven by HTLV-1 long terminal repeat (LTR) was transfected into lymphocytic H9 cells with neo gene, and cell l...
Huaqing Wang, Huaqing Wang, Akiko Sakurai, Boonruang Khamsri, Tsuneo Uchiyama, Hongxi Gu, Akio Adachi, Mikako Fujita
Microbes and Infection   7 385-390   Mar 2005
We examined the steady-state expression in cells of four accessory proteins of human immunodeficiency virus type 1 (HIV-1). For this purpose, a series of single gene expression vectors for these viral proteins were constructed and were monitored f...
Tamiko Nagao, Akiko Yoshida, Akiko Sakurai, Ahmad Piroozmand, Abhay Jere, Mikako Fujita, Tsuneo Uchiyama, Akio Adachi
International journal of molecular medicine   14 1073-1076   Dec 2004
We have established lymphocytic cell lines H9 and M8166 that contain integrated copy of luciferase gene under the control of human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR). While H9 is known to be non-permissive for or inse...
Abhay Jere, Ahmad Piroozmand, Srikanth Tripathy, Ramesh Paranjape, Akiko Sakurai, Mikako Fujita, Akio Adachi
International journal of molecular medicine   14 1087-1090   Dec 2004
The impact of human immunodeficiency virus type 1 (HIV-1) Nef on viral infectivity was evaluated by characterization of chimeric clones. Chimera with respect to the nef gene were constructed between subtypes B and C, and monitored for their replic...
Ahmad Piroozmand, A. Hajime Koyama, Yoshiko Shimada, Mikako Fujita, Tsutomu Arakawa, Akio Adachi
International journal of molecular medicine   14 641-645   Oct 2004
The sensitivity of a Us3-deletion mutant virus of herpes simplex virus type 1 (HSV-1) to consensus interferon (IFN) was compared with that of parental wild-type (wt) and the repaired viruses. Although one-step growth of the Us3-deficient virus in ...
Akiko Sakurai, Abhay Jere, Akiko Yoshida, Takeshi Yamada, Aikichi Iwamoto, Akio Adachi, Mikako Fujita
Microbes and Infection   6 799-805   Jul 2004
We analyzed the function of human immunodeficiency virus type 1 (HIV-1) vif gene from Japanese long-term nonprogressors (LTNPRs) and progressors (PRs) for acquired immunodeficiency syndrome (AIDS). We constructed a basic HIV-1 infectious clone, wh...
Mikako Fujita, Hirofumi Akari, Akiko Sakurai, Akiko Yoshida, Tomoki Chiba, Keiji Tanaka, Klaus Strebel, Akio Adachi
Microbes and Infection   6 791-798   Jul 2004
While the Vif protein of human immunodeficiency virus type 1 (HIV-1) is essential for viral replication in non-permissive cells, it is rapidly degraded intracellularly. We have previously suggested that the rapid turn-over of Vif is biologically m...
Hirofumi Akari, Hirofumi Akari, Mikako Fujita, Sandra Kao, Mohammad A. Khan, Miranda Shehu-Xhilaga, Akio Adachi, Klaus Strebel, Klaus Strebel
Journal of Biological Chemistry   279 12355-12362   Mar 2004
The human immunodeficiency virus type-1 Vif protein has a crucial role in regulating viral infectivity. However, we found that newly synthesized Vif is rapidly degraded by cellular proteases. We tested the dose dependence of Vif in non-permissive ...
Mikako Fujita, Akiko Yoshida, Akiko Sakurai, Junko Tatsuki, Fumiko Ueno, Hirofumi Akari, Akio Adachi
International journal of molecular medicine   11 641-644   May 2003
Susceptibility of HSC-F, a cynomolgus macaque cell line immortalized by Herpesvirus saimiri, to infection with various primate immunodeficiency viruses were monitored. While NL432 clone of human immunodeficiency virus type 1 (HIV-1) did not grow a...
Fumiko Ueno, Hiroshi Shiota, Maki Miyaura, Akiko Yoshida, Akiko Sakurai, Junko Tatsuki, A. Hajime Koyama, Hirofumi Akari, Akio Adachi, Mikako Fujita
Microbes and Infection   5 387-395   Apr 2003
Mutants of human immunodeficiency virus type 2 (HIV-2) carrying a frame-shift mutation in vpx, vpr, and in both genes were monitored for their growth potentials in a newly established lymphocytic cell line, HSC-F. Worthy of note, the replication o...
Mikako Fujita, Akiko Sakurai, Akiko Yoshida, Maki Miyaura, A. Hajime Koyama, Koji Sakai, Akio Adachi
Journal of Virology   77 1626-1632   Jan 2003
A hydrophilic region consisting of strikingly clustered charged amino acids is present at the center of human immunodeficiency virus type 1 (HIV-1) Vif. In this study, the role for this central hydrophilic region (E88WRKKR93) in the virus replicat...
Akio Adachi, Fumiko Ueno, Mikako Fujita
Nippon rinsho. Japanese journal of clinical medicine   61 Suppl 3 497-502   Jan 2003
Mikako Fujita, Akiko Sakurai, Akiko Yoshida, Sora Matsumoto, Maki Miyaura, Akio Adachi
Microbes and Infection   4 621-624   Jun 2002
Mutations were introduced into the region encoding the two cysteine and nearby amino acid residues of human immunodeficiency virus type 1 (HIV-1) Vif protein and, 12 single-amino-acid viral mutants were constructed. Determination of their growth c...
Mikako Fujita, Sora Matsumoto, Akiko Sakurai, Naoya Doi, Maki Miyaura, Akiko Yoshida, Akio Adachi
Microbes and Infection   4 1203-1207   Jan 2002
The vif gene of human immunodeficiency virus type 1 (HIV-1) is essential for virus growth in non-permissive cells such as H9. To elucidate the mechanism of action of the Vif protein, vif mutants, which show trans-dominant negative effects on the r...
A. Adachi, M. Miyaura, A. Sakurai, A. Yoshida, A. H. Koyama, M. Fujita
International journal of molecular medicine   8 641-644   Dec 2001
NM-3 is a prototype of chimeric virus between simian and human immunodeficiency viruses (SHIV). It grows in monkey lymphocytic cells in vitro and in vivo as well as in human cells. A mutant designated NM3-E65, which lacks expression of the entire ...
Mikako Fujita, Akiko Sakurai, Naoya Doi, Maki Miyaura, Akiko Yoshida, Koji Sakai, Akio Adachi
Microbes and Infection   3 1093-1099   Nov 2001
Eleven in-frame vif gene mutants of HIV type 1 produced in non-permissive cells were examined for their replication potentials in various CD4-positive and -negative cell lines. Virus replication for each mutant was monitored by using several singl...
M. Fujita, A. Yoshida, M. Miyaura, A. Sakurai, H. Akari, A. H. Koyama, A. Adachi
Journal of Virology   75 10527-10531   Oct 2001
Hybrid viruses between human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus strain mac (SIVMAC) are invaluable to various fields of HIV-1 research. To date, however, no replication-competent HIV-1 strain containing the gag...
Takatoshi Nagate, Takatoshi Nagate, T. Akashi, K. Numata, K. Sugita, Y. Kaneda, M. Matsuyama, H. Saito, M. Nozawa, A. Onodera, K. Hanada, T. Kobori, M. Fujita, R. Yamamoto, T. Hiyama, K. Kondo
Chemotherapy   47 157-169   Apr 2001
SC-002 is a novel oral cephalosporin possessing a unique thiadiazolylethenyl moiety at the 3 position. In the present study, it was the most active against gram-positive bacteria among oral cephalosporins such as cefdinir (CFDN), cefpodoxime, cefd...
Kyu Bom Koh, Maki Miyaura, Akiko Yoshida, Akiko Sakurai, Mikako Fujita, Akio Adachi
Microbes and Infection   2 1419-1423   Nov 2000
We have previously shown that some of the human immunodeficiency virus type 1 (HIV-1) gag matrix (MA), capsid (CA), and nucleocapsid (NC) mutants display host-cell-dependent replication potential, and that they are defective at the early phase of ...
Kyu Bom Koh, Mikako Fujita, Akio Adachi
Journal of Virological Methods   90 99-102   Oct 2000
Molecular genetics is a powerful tool to analyze the replication cycle of human immunodeficiency virus type 1 (HIV-1). Culture fluids obtained from HIV-1 plasmid-transfected cells by calcium-phosphate co-precipitation were treated with ethylenegly...
Tomoharu Fukumori, Tomoharu Fukumori, Hirofumi Akari, Akiko Yoshida, Mikako Fujita, A. Hajime Koyama, Susumu Kagawa, Akio Adachi
Microbes and Infection   2 1011-1017   Sep 2000
Biological effects of HIV-1 Vpr on CD4+ cells were studied by an infection system. High-titered HIV-1 stocks pseudotyped with vesicular stomatitis virus G protein were prepared and used to inoculate into CD4+ T cells at high multiplicity of infect...
A. Hajime Koyama, Tomoharu Fukumori, Mikako Fujita, Hiroshi Irie, Akio Adachi
Microbes and Infection   2 1111-1117   Sep 2000
In contrast to insect viruses, animal viruses can produce considerable amounts of progeny virus in cells undergoing apoptosis. Nevertheless, viruses in general have acquired the ability to escape apoptosis of infected cells. These facts indicate t...
M. Miyaura, A. Yoshida, A. Sakurai, M. Fujita, A. H. Koyama, A. Adachi
International journal of molecular medicine   6 265-269   Sep 2000
The mature Gag proteins of human immunodeficiency virus type 1 (HIV-1) are major components of infectious virions, and thought to carry out numerous functions throughout the HIV-1 replication cycle. We have recently generated numerous gag gene mut...
A. Yoshida, M. Miyaura, A. Sakurai, T. Fukumori, M. Fujita, H. Akari, A. Adachi
International journal of molecular medicine   6 83-86   Jul 2000
The expression level of major histocompatibility class I (MHC-I) and the extent of down-regulation of MHC-I after an anti-MHC-I antibody treatment in numerous human T-cell leukemia virus type 1 (HTLV-1)-positive and -negative lymphocytic cell line...
A. Yoshida, J. Shimomoto, K. B. Koh, M. Fujita, A. Adachi
International journal of molecular medicine   5 291-294   Mar 2000
We have previously shown that a number of human immunodeficiency virus type 1 (HIV-1) mutants generated in vitro display a replication-defect in a cell-dependent manner. Of the mutants of this category, those of gag, vif, and env mutants do not gr...
Sei Ichi Mizushima, Mikako Fujita, Takaomi Ishida, Sakura Azuma, Katsuaki Kato, Momoki Hirai, Masami Otsuka, Tadashi Yamamoto, Jun Ichiro Inoue
Gene   207 135-140   Jan 1998
A cDNA encoding the human homolog of the tumor necrosis factor receptor-associated factor 5 (TRAF5) protein has been molecularly cloned from a cDNA library of Human Daudi B cell line. The sequence analysis revealed that the cDNA encoded a protein ...
藤田美歌子, 大塚雅巳
有機合成化学協会誌   55(8) 697-704   Aug 1997
NF-κB, HIV-EP1, Sp1, and TBP-E1A are transcriptional proteins involved in the long terminal repeat-directed expression of huaman immunodeficiency virus. Inhibitory effect of eighteen compounds against NF-κB, HIV-EP1, Sp1, and E1A was studied. The ...
Masami Otsuka, Mikako Fujita, Yukio Sugiura, Tadashi Yamamoto, Jun Ichiro Inoue, Toshio Maekawa, Shunsuke Ishii
Bioorganic and Medicinal Chemistry   5 205-215   Jan 1997
NF-κB, HIV-EP1, Sp1, and E1A are transcriptional proteins involved in the long terminal repeat-directed expression of HIV-1. The inhibitory effect of 18 dimethylaminopyridine-based compounds against these regulatory proteins was studied. Experimen...
Mikako Fujita, Masami Otsuka, Yukio Sugiura
Journal of Medicinal Chemistry   39 503-507   Jan 1996
HIV-EP1 is a C2H2 type zinc finger protein which binds to DNA κB site present in the long terminal repeat of HIV provirus. Previously we have reported zinc chelators having histidine-pyridine-histidine skeleton and were successful in inhibiting th...
Masami Otsuka, Mikako Fujita, Tsutomu Aoki, Shunsuke Ishii, Yukio Sugiura, Tadashi Yamamoto, Jun Ichiro Inoue
Journal of Medicinal Chemistry   38 3264-3270   Dec 1995
Both HIV-EP1 (also called PRDII-BF1 or MBP-1), a zinc finger protein, and NF-κB, a Rel family protein, bind to κB site present in the enhancer of multiple cellular and viral genes involved in immune function and inflammatory response including HIV...
Mikako Fujita, Kohei Nimura, Takeo Kobori, Tamejiro Hiyama, Kiyosi Kondo
Heterocycles   41 2413-2417   Nov 1995
The Hurd-Mori reaction of N-ethoxycarbonyl- or p-toluenesulfonylhydrazones of 1,2-alkanediones (1) gave Δ3-1,2,3-thiadiazolin-1-ones (2) as each sole isolable product. Upon HCl treatment 2b was converted into 1,2,3-thiadiazole, an expected product...
Masami Otsuka, Mikako Fujita, Yukio Sugiura, Shunsuke Ishii, Tsutomu Aoki, Tadashi Yamamoto, Jun Ichiro Inoue
Journal of Medicinal Chemistry   37 4267-4269   Dec 1994
Takeo Kobori, Mikako Fujita, Rumi Yamamoto, Tamejiro Hiyama, Kiyosi Konda, Kazuo Numata, Kazuo Numata, Kazuhiko Sugita, Kazuhiko Sugita, Toshi Akashi, Toshi Akashi, Yoshie Kaneda, Yoshie Kaneda, Takatoshi Nagate, Takatoshi Nagate, Kazunori Hanada, Kazunori Hanada
Bioorganic and Medicinal Chemistry Letters   3 2225-2230   Jan 1993
A series of cephalosporins possessing a [(Z-2-(1,2,3-thiadiazolyl)ethenl] moiety at C-3 were synthesized and their biological properties were examined. SC-002 (1a) exhibited excellent activity against both Gram-positive and Gram-negative bacteria....
Mikako Fujita, Takeo Kobori, Tamejiro Hiyama, Kiyosi Kondo
Heterocycles   36 33-36   Jan 1993
Various α-substituted (Y) acetone hydrazones were subjected to the Hurd-Mori reaction to give the 4-methyl-5-Y-substituted 1,2,3-thiadiazoles and/or 4-Y-CH2 derivatives. The ratio of the two products changed drastically depending on the kind of th...

Misc

 
Takeo Kobori, Mikako Fujita, Tamejiro Hiyama, Kiyosi Kondo
Synlett   1992 95-96   Jan 1992
© 1992 Georg Thieme Verlag. All rights reserved. 4-Formyl-1,2,3-thiadiazole(1) was synthesized in high overall yield from 2-oxopropanal bis(ethoxycarbonylhydrazone)(3) and thionyl chloride through the Hurd-Mori reaction.
Takahiro Tezuka, Katsunori Sasaki, Nozomu Narita, Mikako Fujita, Keiichi Ito, Takashi Otsuka
Tetrahedron Letters   30 963-966   Jan 1989
Heating α-azohydroperoxide (1) (ca. 10-3 M) in benzene under reflux with bubbling inert gas for 20 - 23 hours affords biphenyls (2) in high yields (70 - 90%). A mechanism involving an induced decomposition radical chain reaction is suggested. © 1989.
Wataru Ando, Mikako Fujita, Hitoaki Yoshida, Akira Sekiguchi
Journal of the American Chemical Society   110 3310-3311   May 1988

Conference Activities & Talks

 
島垣和功, 古賀涼子, 藤野悠那, CIFTCI Halil Ibrahim, 山本充奈美, 大塚雅巳, 山口佳宏, 藤田美歌子
日本エイズ学会誌   20 Nov 2018   
加茂真宏, 安野拓実, 高橋恭子, 大塚雅巳, 大江知之, 増野匡彦, 藤田美歌子
日本エイズ学会誌   20 Nov 2018   
安楽健作, 立石大, 古賀涼子, 福田亮太, 坂本亜里紗, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2018   
藤田美歌子, 大塚雅巳
日本がん分子標的治療学会学術集会プログラム・抄録集   16 Apr 2018   
島垣和功, 古賀涼子, HALIL IbrahimCiftci, 大塚雅巳, 山口佳宏, 藤田美歌子
日本エイズ学会誌   20 Nov 2017   
立石大, 門出和精, 古賀涼子, 林祐也, 東大志, 本山敬一, 有馬英俊, 安楽健作, 藤田美歌子, 大塚雅巳
メディシナルケミストリーシンポジウム講演要旨集   4 Oct 2017   
安野拓実, CHIFTCI Halil Ibrahim, 大江知之, 高橋恭子, 藤田美歌子, 中村成夫, 大塚雅巳, 増野匡彦
メディシナルケミストリーシンポジウム講演要旨集   4 Oct 2017   
立石大, 門出和精, 村尾直樹, 古賀涼子, 林祐也, 東大志, 本山敬一, 有馬英俊, 安楽健作, 藤田美歌子, 大塚雅巳
万有福岡シンポジウム   3 Jun 2017   
加茂真宏, 立石大, 山本充奈美, 岡本良成, 森川裕子, 三隅将吾, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2017   
立石大, 門出和精, 村尾直樹, 古賀涼子, 林祐也, 東大志, 本山敬一, 有馬英俊, 安楽健作, 藤田美歌子, 大塚雅巳
日本薬学会年会要旨集(CD-ROM)   2017   
古賀涼子, ラドワン モハメドオスマン, 江島智彦, 金丸陽亮, 柴田佑里, 田口祐, 井上純一郎, 大塚雅已, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2017   
野口慶, 折戸公彦, 三好淳子, 森岡基浩, タハ シュハタアリ, 藤田美歌子, 大塚雅巳
脳循環代謝(Web)   2017   
平尚未, タハ ファロウクシェハタアリ, 古賀涼子, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2017   
加茂真宏, 立石大, 山本充奈美, 岡本良成, 森川裕子, 三隅将吾, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2016   
平尚未, アリ タハファロウクシェハタ, 古賀涼子, 大塚雅巳, 藤田美歌子
日本薬学会九州支部大会講演要旨集   19 Nov 2016   
本邑健太, 岡本良成, 古賀涼子, 馬塲菜々美, 藤田美歌子, 梅澤一夫, 大塚雅巳
日本薬学会九州支部大会講演要旨集   19 Nov 2016   
伊東理生, 安田健二, 西並隆, 古賀涼子, 藤田美歌子, 切替照雄, 山縣ゆり子, 黒崎博雅, 山口佳宏
日本薬学会九州支部大会講演要旨集   Nov 2016   
古賀涼子, RADWAN Mohamed O., 江島智彦, 金丸陽亮, 柴田佑里, 田口祐, 井上純一郎, 大塚雅巳, 藤田美歌子
日本分子生物学会年会プログラム・要旨集(Web)   2016   
加茂真宏, 立石大, 山本充奈美, 岡本良成, 森川裕子, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2016   
立石大, 門出和精, 村尾直樹, 古賀涼子, 林祐也, 東大志, 本山敬一, 有馬英俊, 安楽健作, 藤田美歌子, 大塚雅巳
日本薬学会年会要旨集(CD-ROM)   2016   
藤田美歌子, CIFTCI Halil Ibrahim, 藤野悠那, 古賀涼子, 山本充奈美, 大塚雅巳
日本エイズ学会誌   20 Nov 2015   
立石大, 門出和精, 村尾直樹, 古賀涼子, 林祐也, 東大志, 本山敬一, 有馬英俊, 安楽健作, 藤田美歌子, 大塚雅巳
生体膜と薬物の相互作用シンポジウム講演要旨集   19 Nov 2015   
古賀涼子, 江島智彦, 金丸陽亮, 柴田佑里, 田口祐, 井上純一郎, 大塚雅巳, 藤田美歌子
メディシナルケミストリーシンポジウム講演要旨集   1 Nov 2015   
立石大, 門出和精, 村尾直樹, 古賀涼子, 林祐也, 東大志, 本山敬一, 有馬英俊, 安楽健作, 藤田美歌子, 大塚雅巳
メディシナルケミストリーシンポジウム講演要旨集   1 Nov 2015   
藤田美歌子
抗ウイルス宿主因子を基盤とする新規抗HIV戦略の開発・確立に向けた系統的研究 平成24-26年度 総合研究報告書 平成26年度 総括・分担研究報告書   2015   
加茂真宏, 立石大, 山本充奈美, 岡本良成, 森川裕子, 三隅将吾, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2015   
立石大, 安楽健作, 村尾直樹, 門出和精, 原田信志, 古賀涼子, 岡本良成, 藤田美歌子, 大塚雅巳
日本薬学会年会要旨集(CD-ROM)   2015   
古賀涼子, 江島智彦, 金丸陽亮, 柴田佑里, 田口祐, 井上純一郎, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2015   
加茂真宏, 立石大, 岡本良成, 森川裕子, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2014   
立石大, 安楽健作, 村尾直樹, 古賀涼子, 岡本良成, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2014   
安楽健作, 立石大, 古賀涼子, 岡本良成, 藤田美歌子, 大塚雅巳
メディシナルケミストリーシンポジウム講演要旨集   7 Nov 2014   
加茂真宏, 立石大, 岡本良成, 森川裕子, 大塚雅巳, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   31 Oct 2014   
大杉剛生, 若宮誠, 森川沙樹, 中村直子, 川辺正等美, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   31 Oct 2014   
藤野悠那, 山本充奈美, CIFTCI Halil Ibrahim, 島垣和功, 古賀涼子, 大塚雅巳, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   31 Oct 2014   
安野拓実, 高橋恭子, 大江知之, 藤田美歌子, 中村成夫, 増野匡彦
日本薬学会関東支部大会講演要旨集   30 Sep 2014   
古賀涼子, 江島智彦, 金丸陽亮, 柴田佑里, 田口祐, 井上純一郎, 大塚雅巳, 藤田美歌子
日本分子生物学会年会プログラム・要旨集(Web)   2014   
山本充奈美, 藤野悠那, 古賀涼子, チッフチ ハリル, 三隅将吾, 大塚雅巳, 藤田美歌子
日本分子生物学会年会プログラム・要旨集(Web)   2014   
田中亜友美, 岡本良成, 藤田美歌子, 梅澤和夫, 玉野井冬彦, 大塚雅巳
日本薬学会年会要旨集(CD-ROM)   2014   
加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2014   
立石大, 安楽健作, 古賀涼子, 岡本良成, 藤田美歌子, 大塚雅巳
日本薬学会年会要旨集(CD-ROM)   2014   
藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2014   
古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2014   
藤田美歌子
抗ウイルス宿主因子を基盤とする新規抗HIV戦略の開発・確立に向けた系統的研究 平成25年度総括・分担研究報告書   2014   
古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
日本薬学会九州支部大会講演要旨集   20 Nov 2013   
加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
日本薬学会九州支部大会講演要旨集   20 Nov 2013   
井田智弓, 岡本良成, 藤田美歌子, 黒崎博雅, 大塚雅巳
日本薬学会九州支部大会講演要旨集   20 Nov 2013   
高宗暢暁, 山本充奈美, 原田圭輔, 藤田美歌子, 大塚雅巳, 杉本幸彦, 庄司省三, 三隅将吾
日本エイズ学会誌   20 Nov 2013   
加茂真宏, 岡本良成, 大塚雅巳, 藤田美歌子
メディシナルケミストリーシンポジウム講演要旨集   1 Nov 2013   
立石大, 安楽健作, 古賀涼子, 岡本良成, 藤田美歌子, 大塚雅巳
メディシナルケミストリーシンポジウム講演要旨集   1 Nov 2013   
古賀涼子, 江島智彦, 金丸陽亮, 田口祐, 柴田佑里, 井上純一郎, 大塚雅巳, 藤田美歌子
メディシナルケミストリーシンポジウム講演要旨集   1 Nov 2013   
山本充奈美, 野間口雅子, 古賀涼子, 岩谷靖雅, 高宗暢暁, 三隅将吾, 大塚雅巳, 足立昭夫, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   29 Oct 2013   
高宗暢暁, 山本充奈美, 原田圭輔, 藤田美歌子, 大塚雅巳, 杉本幸彦, 庄司省三, 三隅将吾
日本ウイルス学会学術集会プログラム・抄録集   29 Oct 2013   
藤野悠那, 古賀涼子, 大塚雅巳, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   29 Oct 2013   
藤田美歌子
抗ウイルス宿主因子を基盤とする新規HIV戦略の開発・確立に向けた系統的研究 平成24年度総括・分担研究報告書   2013   
安楽健作, 立石大, 古賀涼子, 東大志, 本山敬一, 有馬英俊, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集(CD-ROM)   2013   
立石大, 安楽健作, 古賀涼子, 藤田美歌子, 大塚雅巳
日本薬学会年会要旨集(CD-ROM)   2013   
藤田美歌子
日本薬学会九州支部大会講演要旨集   25 Nov 2012   
園田祥子, 安楽健作, 古賀涼子, 田口祐, 井上純一郎, 岡本良成, 藤田美歌子, 大塚雅巳
日本薬学会九州支部大会講演要旨集   25 Nov 2012   
立石大, 安楽健作, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2012   
藤野悠那, 三宅在子, 古賀涼子, 川村宗吾, 大出裕高, 岩谷靖雅, 野間口雅子, 足立昭夫, 大塚雅巳, 宮崎恭行, 藤田美歌子
日本エイズ学会誌   20 Nov 2012   
藤田美歌子, 古賀涼子, 金丸陽亮, 江島智彦, 園田祥子, 安楽健作, 田口祐, 井上純一郎, 大塚雅巳
メディシナルケミストリーシンポジウム講演要旨集   1 Nov 2012   
三宅在子, 藤野悠那, 古賀涼子, 川村宗吾, 大出裕高, 岩谷靖雅, 野間口雅子, 大塚雅巳, 足立昭夫, 藤田美歌子, 宮崎恭行
日本ウイルス学会学術集会プログラム・抄録集   31 Oct 2012   
藤田美歌子, 野間口雅子, 古賀涼子, 藤野悠那, 大塚雅巳, 足立昭夫
日本ウイルス学会学術集会プログラム・抄録集   31 Oct 2012   
安楽健作, 筑葉晃一, 立石大, 藤田美歌子, 舛田岳史, 岡本良成, 大塚雅巳
反応と合成の進歩シンポジウム講演要旨集   15 Oct 2012   
安楽健作, 立石大, 藤田美歌子, 大塚雅巳
日本薬学会年会要旨集   5 Mar 2012   
肥田知浩, 金丸陽亮, 岡本良成, 藤田美歌子, 大塚雅巳
日本薬学会九州支部大会講演要旨集   25 Nov 2011   
藤田美歌子, 安楽健作, 大塚雅巳
日本エイズ学会誌   20 Nov 2011   
安楽健作, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2011   
福田亮太, 安楽健作, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2010   
藤田美歌子, 大塚雅巳, 高橋恭子, 中村成夫, 増野匡彦
日本エイズ学会誌   20 Nov 2010   
篠原舞, 竹内由紀, 高橋恭子, 藤田美歌子, 大塚雅巳, 中村成夫, 増野匡彦
メディシナルケミストリーシンポジウム講演要旨集   18 Oct 2010   
安楽健作, 福田亮太, 藤田美歌子, 大塚雅巳
メディシナルケミストリーシンポジウム講演要旨集   18 Oct 2010   
藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   15 Oct 2010   
安楽健作, 福田亮太, 大塚雅巳, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   15 Oct 2010   
工藤康太, 安楽健作, 岡本良成, 藤田美歌子, 河野隆幸, 森岡基浩, 倉津純一, 大塚雅巳
日本薬学会年会要旨集   5 Mar 2010   
福田亮太, 安楽健作, 大塚雅巳, 藤田美歌子
日本エイズ学会誌   20 Nov 2009   
藤田美歌子, 安楽健作, 大塚雅巳
日本ウイルス学会学術集会プログラム・抄録集   1 Oct 2009   
江島智彦, 岡本良成, 大塚雅巳, 藤田美歌子
日本薬学会年会要旨集   5 Mar 2009   
江島智彦, 岡本良成, 大塚雅巳, 藤田美歌子
日本分子生物学会年会講演要旨集   2009   
廣田真友子, 入江佳奈子, 尾田一貴, 岡本良成, 合田仁, 井上純一郎, 藤田美歌子, 大塚雅巳
日本分子生物学会年会講演要旨集   2009   
藤田美歌子, 安楽健作, 福田亮太, 大塚雅巳
日本エイズ学会誌   20 Nov 2008   
安楽健作, 大塚雅巳, 藤田美歌子
日本ウイルス学会学術集会プログラム・抄録集   1 Oct 2008   
藤田美歌子, 大塚雅巳, 野間口雅子, 足立昭夫
日本ウイルス学会学術集会プログラム・抄録集   1 Oct 2008   
入江佳奈子, 尾田一貴, 岡本良成, 藤田美歌子, 大塚雅巳, 井上純一郎
反応と合成の進歩シンポジウム講演要旨集   20 Oct 2007   
藤田美歌子, 長尾多美子, 足立昭夫
日本エイズ学会誌   20 Nov 2006   
藤田美歌子, 足立昭夫
日本薬学会九州支部大会講演要旨集   15 Nov 2006   
藤田美歌子, KHAMSRI Boonruang, 山下知輝, 鎌田和弥, PIROOZMAND Ahmad, 長尾多美子, 土肥直哉, 足立昭夫
日本ウイルス学会学術集会プログラム・抄録集   1 Nov 2006   
山下知輝, 鎌田和弥, KHAMSRI Boonruang, 八町和樹, 藤田美歌子, 内山恒夫, 足立昭夫
日本ウイルス学会学術集会プログラム・抄録集   1 Nov 2006   
鎌田和弥, 内山恒夫, 山下知輝, PIROOZMAND Ahmad, KHAMSRI Boonruang, 長尾多美子, 藤田美歌子, 足立昭夫
日本ウイルス学会学術集会プログラム・抄録集   1 Nov 2005   
藤田美歌子, 足立昭夫
日本エイズ学会誌   20 Nov 2004   
藤田美歌子, ブンルアン カムセー, 櫻井明子, ジェレ アブハイ, 内山恒夫, 足立昭夫
日本ウイルス学会学術集会プログラム・抄録集   1 Nov 2004   
小山一, 島田佳子, PIROOZMAND A, 藤田美歌子, 入江宏, 足立昭夫
日本分子生物学会年会プログラム・講演要旨集   25 Nov 2003   
藤田美歌子, 桜井明子, 吉田亜希子, JERE A J, ARMAD P, 小山一, 明里宏文, 千葉智樹, 田中啓二
日本分子生物学会年会プログラム・講演要旨集   25 Nov 2003   
藤田美歌子, 宮浦麻記, 吉田亜希子, 桜井明子, 足立昭夫
日本エイズ学会誌   20 Nov 2001   
藤田美歌子, 桜井明子, 宮浦麻記, 吉田亜希子, 足立昭夫
日本エイズ学会誌   20 Nov 2001   
藤田美歌子, 吉田亜希子, 宮浦麻記, 桜井明子, 足立昭夫
日本エイズ学会誌   20 Nov 2001   
加藤美穂, 藤田美歌子, 袖岡幹子, 青山靖典, 朝海怜
日本薬学会年会要旨集   5 Mar 2001   
藤田美歌子, 桜井明子, 宮浦麻記, 吉田亜希子, 足立昭夫
日本エイズ学会誌   20 Nov 2000