2019年3月
Impact of inline magnetic fields on dose distributions for VMAT in lung tumor.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
- ,
- ,
- 巻
- 59
- 号
- 開始ページ
- 100
- 終了ページ
- 106
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.ejmp.2019.03.003
The purpose of this study is to investigate the impact of inline magnetic field on dose distribution for volumetric modulated arc therapy (VMAT) in lung tumors located at the chest wall and mediastinum. Two VMAT plans for a thorax phantom with lung tumors of 1 cm and 2 cm in diameter located at the chest wall were created by a treatment planning system. Next, five clinical VMAT plans for a non-small cell lung cancer (NSCLC) at early stages I and II of 5 cm or less in diameter were also used. The planning target volume (PTV) sizes were in the range from 11.1 to 82.7 cm3. The prescription dose was 60 Gy for D95 in the PTV. The VMAT dose distributions without and with uniform inline magnetic field of 0.5 T and 1.0 T were calculated using the Monte Carlo method. The dose distributions were analyzed by dose volume histograms, dose differences, and dose indices. In all VMAT plans, the PTV dose was enhanced by inline magnetic field. The dose enhancement was larger with 1.0 T than with 0.5 T. In phantom plans, D98 in the PTV with 0.5 T and 1.0 T increased by 2.9-6.6 Gy and 3.9-9.8 Gy, respectively, in comparison with that at 0 T. Similarly, in clinical plans, it increased by 2.2-6.0 Gy and 3.9-10.7 Gy, respectively. Thus, the VMAT with the inline magnetic field was proved useful for the dose enhancement in the lung tumor located at the chest wall and mediastinum.
- リンク情報
- ID情報
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- DOI : 10.1016/j.ejmp.2019.03.003
- ISSN : 1120-1797
- PubMed ID : 30928057