向野晃弘 (MUKAINO AKIHIRO) - マイポータル

基本情報

所属: 富山大学和漢診療学講座助教

学位: 医学博士(2016年3月長崎大学医歯薬学総合研究科医療科学)

J-GLOBAL ID: 201601015894059827
researchmap会員ID: 7000016891

研究キーワード

研究分野

ライフサイエンス / 神経内科学 / 神経免疫

経歴

2023年7月 - 現在

富山大学医学部, 和漢診療学講座, 助教
2021年4月 - 2023年6月

富山大学, 和漢診療学講座, 診療助手
2017年4月 - 2021年3月

熊本大学病院, 分子神経治療学寄附講座, 特任助教
2014年10月 - 2016年3月

長崎大学病院, 第一内科神経内科, 特任助教

委員歴

2017年 - 現在

日本自律神経学会, 評議員

受賞

2018年9月

Young Neuroimmunologist Award, 日本神経免疫学会学術集会

向野晃弘
2016年9月

Young Neuroimmunologist Award, 日本神経免疫学会学術集会

向野晃弘

主要な論文

Multicenter, randomized, double-blind, placebo-controlled phase 3 study of mogamulizumab with open-label extension study in a minimum number of patients with human T-cell leukemia virus type-1-associated myelopathy.

Tomoo Sato, Masahiro Nagai, Osamu Watanabe, Tatsuro Misu, Norihiro Takenouchi, Ryuichi Ohkubo, Satoshi Ishihara, Yoshio Tsuboi, Masahisa Katsuno, Masanori Nakagawa …

Journal of neurology 271(6) 3471-3485 2024年6月査読有り
The Presence of Ganglionic Acetylcholine Receptor Antibodies in Sera from Patients with Functional Gastrointestinal Disorders: A Preliminary Study.

Shunya Nakane, Akihiro Mukaino, Yoshiaki Okumura, Hiroaki Hirosawa, Osamu Higuchi, Hidenori Matsuo, Mosaburo Kainuma, Yuji Nakatsuji

Journal of personalized medicine 14(5) 2024年4月30日査読有り
Combination of immunotherapy and Kampo medicines for a patient with autoimmune autonomic ganglionopathy

Akihiro Mukaino, Makoto Fujimoto, Mosaburo Kainuma, Shunya Nakane, Yutaka Shimada

Traditional & Kampo Medicine 2023年1月20日査読有り筆頭著者責任著者
重度の体感幻覚症，アパシーに抑肝散加陳皮半夏が有効であったParkinson症候群の1例．

向野晃弘, 藤本誠, 貝沼茂三郎, 渡り英俊, 柴原直利, 嶋田豊

日本東洋医学会雑誌 74(3) 233-242 2023年査読有り筆頭著者責任著者
Macroglossia in rapidly progressive inclusion body myositis.

Yoshimune Yamasaki, Akihiro Mukaino, Satoshi Yamashita, Yousuke Takeuchi, Nozomu Tawara, Ryoji Yoshida, Yumi Honda, Taro Yamashita, Asako Kakimoto, Hidetsugu Ueyama …

Neuropathology : official journal of the Japanese Society of Neuropathology 2022年11月8日査読有り責任著者
Intravenous cyclophosphamide treatment for systemic lupus erythematosus with severe autonomic disorders confirmed by head-up tilt table test: A case series.

Masataka Umeda, Hiroaki Kawano, Yushiro Endo, Ayuko Takatani, Tomohiro Koga, Kunihiro Ichinose, Hideki Nakamura, Akihiro Mukaino, Osamu Higuchi, Shunya Nakane …

Modern rheumatology case reports 6(1) 47-51 2022年1月7日査読有り
A novel murine model of autoimmune dysautonomia by α3 nicotinic acetylcholine receptor immunization.

Makoto Yamakawa, Shunya Nakane, Eikichi Ihara, Nozomu Tawara, Hiroko Ikeda, Yoko Igarashi, Yoshihiro Komohara, Koutaro Takamatsu, Tokunori Ikeda, Yusuke Tomita …

Frontiers in neuroscience 16 1006923-1006923 2022年査読有り
Effectiveness of treatment for 31 patients with seropositive autoimmune autonomic ganglionopathy in Japan

Toshiyuki Hayashi, Shunya Nakane, Akihiro Mukaino, Osamu Higuchi, Makoto Yamakawa, Hidenori Matsuo, Kazumi Kimura

Therapeutic Advances in Neurological Disorders 15 175628642211100-175628642211100 2022年1月査読有り
Association between neurosarcoidosis with autonomic dysfunction and anti-ganglionic acetylcholine receptor antibodies.

Makoto Oishi, Akihiro Mukaino, Misako Kunii, Asami Saito, Yukimasa Arita, Haruki Koike, Osamu Higuchi, Yasuhiro Maeda, Norio Abiru, Naohiro Yamaguchi …

Journal of neurology 268(11) 4265-4279 2021年4月21日査読有り責任著者
gAChR antibodies in children and adolescents with acquired autoimmune dysautonomia in Japan.

Makoto Yamakawa, Mari Watari, Ken-Ichi Torii, Ichiro Kuki, Masashi Miharu, Momoko Kawazu, Akihiro Mukaino, Osamu Higuchi, Yasuhiro Maeda, Tokunori Ikeda …

Annals of clinical and translational neurology 8(4) 790-799 2021年4月査読有り
Antibodies to the α3 subunit of the ganglionic-type nicotinic acetylcholine receptors in patients with autoimmune encephalitis.

Makoto Yamakawa, Akihiro Mukaino, Akio Kimura, Yuki Nagasako, Yuki Kitazaki, Yasushi Maeda, Osamu Higuchi, Koutaro Takamatsu, Mari Watari, Nobuaki Yoshikura …

Journal of neuroimmunology 349 577399-577399 2020年12月15日査読有り
Autoimmune gastrointestinal dysmotility: the interface between clinical immunology and neurogastroenterology.

Shunya Nakane, Akihiro Mukaino, Eikichi Ihara, Yoshihiro Ogawa

Immunological medicine 44(2) 1-12 2020年7月27日査読有り
Behçet's Disease with Severe Autonomic Disorders Developing after Herpes Zoster.

Serina Koto, Masataka Umeda, Hiroaki Kawano, Yushiro Endo, Toshimasa Shimizu, Tomohiro Koga, Kunihiro Ichinose, Hideki Nakamura, Akihiro Mukaino, Osamu Higuchi …

Internal medicine (Tokyo, Japan) 59(8) 1099-1104 2020年4月15日査読有り
A comprehensive analysis of the clinical characteristics and laboratory features in 179 patients with autoimmune autonomic ganglionopathy.

Shunya Nakane, Akihiro Mukaino, Osamu Higuchi, Maeda Yasuhiro, Koutaro Takamatsu, Makoto Yamakawa, Mari Watari, Nozomu Tawara, Kei-Ichi Nakahara, Atsushi Kawakami …

Journal of autoimmunity 108 102403-102403 2020年3月査読有り
Detecting gastrointestinal manifestations in patients with systemic sclerosis using anti-gAChR antibodies.

Shunya Nakane, Masataka Umeda, Shin-Ya Kawashiri, Akihiro Mukaino, Kunihiro Ichinose, Osamu Higuchi, Yasuhiro Maeda, Hideki Nakamura, Hidenori Matsuo, Atsushi Kawakami

Arthritis research & therapy 22(1) 32-32 2020年2月21日査読有り
Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases.

Michie Imamura, Akihiro Mukaino, Koutaro Takamatsu, Hiroto Tsuboi, Osamu Higuchi, Hideki Nakamura, Saori Abe, Yukio Ando, Hidenori Matsuo, Tadashi Nakamura …

International journal of molecular sciences 21(4) 2020年2月16日査読有り
Anti-ganglionic AChR antibodies in Japanese patients with motility disorders.

Akihiro Mukaino, Hitomi Minami, Hajime Isomoto, Hitomi Hamamoto, Eikichi Ihara, Yasuhiro Maeda, Osamu Higuchi, Tohru Okanishi, Yohei Kokudo, Kazushi Deguchi …

Journal of gastroenterology 53(12) 1227-1240 2018年12月査読有り
Autoimmune autonomic ganglionopathy: an update on diagnosis and treatment.

Shunya Nakane, Akihiro Mukaino, Osamu Higuchi, Mari Watari, Yasuhiro Maeda, Makoto Yamakawa, Keiichi Nakahara, Koutaro Takamatsu, Hidenori Matsuo, Yukio Ando

Expert review of neurotherapeutics 18(12) 953-965 2018年12月査読有り
Postural Orthostatic Tachycardia in a Patient with Type 2 Diabetes with Diabetic Neuropathy.

Yoichi Tomichi, Hiroaki Kawano, Akihiro Mukaino, Akiyo Chiba, Yoshiyuki Doi, Shuji Arakawa, Takashi Ishimatsu, Satoki Fukae, Norio Abiru, Koji Maemura

International heart journal 59(6) 1488-1490 2018年11月28日査読有り
Novel anti-suprabasin antibodies may contribute to the pathogenesis of neuropsychiatric systemic lupus erythematosus.

Kunihiro Ichinose, Kaname Ohyama, Kaori Furukawa, Osamu Higuchi, Akihiro Mukaino, Katsuya Satoh, Shunya Nakane, Toshimasa Shimizu, Masataka Umeda, Shoichi Fukui …

Clinical immunology (Orlando, Fla.) 193 123-130 2018年8月査読有り
Autoimmune postural orthostatic tachycardia syndrome.

Mari Watari, Shunya Nakane, Akihiro Mukaino, Makoto Nakajima, Yukiko Mori, Yasuhiro Maeda, Teruaki Masuda, Koutaro Takamatsu, Yanosuke Kouzaki, Osamu Higuchi …

Annals of clinical and translational neurology 5(4) 486-492 2018年4月査読有り
Ganglionic acetylcholine receptor autoantibodies in patients with autoimmune diseases including primary biliary cirrhosis.

Yasuhiro Maeda, Shunya Nakane, Osamu Higuchi, Hideki Nakamura, Atsumasa Komori, Kiyoshi Migita, Akihiro Mukaino, Masataka Umeda, Kunihiro Ichinose, Mami Tamai …

Modern rheumatology 27(4) 664-668 2017年7月査読有り
Extra-autonomic manifestations in autoimmune autonomic ganglionopathy: a Japanese survey.

Shunya Nakane, Akihiro Mukaino, Yasuhiro Maeda, Osamu Higuchi, Hidenori Matsuo, Yukio Ando

Journal of neurology, neurosurgery, and psychiatry 88(4) 367-368 2017年4月査読有り
[The interface between the immune system and autonomic nervous system].

Shunya Nakane, Akihiro Mukaino, Yukio Ando

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 40(5) 352-360 2017年査読有り
Insights from the ganglionic acetylcholine receptor autoantibodies in patients with Sjögren's syndrome.

Mukaino A, Nakane S, Higuchi O, Nakamura H, Miyagi T, Shiroma K, Tokashiki T, Fuseya Y, Ochi K, Umeda M …

Modern rheumatology 26(5) 708-15 2016年9月査読有り筆頭著者
Ganglionic acetylcholine receptor autoantibodies in patients with Guillain-Barré syndrome.

Nakane S, Higuchi O, Hamada Y, Maeda Y, Mukaino A, Sakai W, Kusunoki S, Matsuo H

Journal of neuroimmunology 295-296 54-9 2016年6月15日査読有り
Association between Anti-Ganglionic Nicotinic Acetylcholine Receptor (gAChR) Antibodies and HLA-DRB1 Alleles in the Japanese Population.

Yasuhiro Maeda, Kiyoshi Migita, Osamu Higuchi, Akihiro Mukaino, Hiroshi Furukawa, Atsumasa Komori, Minoru Nakamura, Satoru Hashimoto, Shinya Nagaoka, Seigo Abiru …

PloS one 11(1) e0146048 2016年査読有り
Clinical features of autoimmune autonomic ganglionopathy and the detection of subunit-specific autoantibodies to the ganglionic acetylcholine receptor in Japanese patients.

Shunya Nakane, Osamu Higuchi, Michiaki Koga, Takashi Kanda, Kenya Murata, Takashi Suzuki, Hiroko Kurono, Masanari Kunimoto, Ken-ichi Kaida, Akihiro Mukaino …

PloS one 10(3) e0118312 2015年査読有り