KITAZAWA SOICHIRO

Profile Information

Affiliation: Assistant Professor, College of Pharmaceutical Sciences, Department of Pharmacy, Ritsumeikan University

Degree: Doctor of science(Ritsumeikan Univ.)

J-GLOBAL ID: 201601010498355128
researchmap Member ID: 7000017188

Research Interests

Structural biology, Structural fluctuation, NMR, Protein

Research Areas

Research History

Apr, 2016

College of pharmaceutical sciences, Ritsumeikan Univ.
Feb, 2015 - Mar, 2016

Center for biotechnology and interdisciplinary studies, Rensselaer polytechnic insititute
Oct, 2015 - Nov, 2015

Research organization of science and technology

Education

- Sep, 2014

General science and engineering, Science and engineering, Ritsumeikan Univ.
- Mar, 2011

Science and engineerign, Science and engineering, Ritsumeikan Univ.
- Mar, 2009

Applied Chemistry, Science and Engineering, Ritsumeikan Univ.

Papers

Dynamic aspects of pressure and temperature-stabilized intermediates of outer surface protein A.

Takuro Wakamoto, Soichiro Kitazawa, Tomoshi Kameda, Ryo Kitahara

Proteins, 88(11) 1423-1433, Nov, 2020
Paramagnetic relaation enhancement-assisted structural characterization of a partially disordered conformation of ubiquitin

Takuro Wakamoto, Teppei Iseya, Soichiro Kitazawa, Nicola J. Baxter, Mike P. Williamson, Ryo Kitahara

Protein Science, 28(11) 1993-2003-2003, Oct, 2019
Pressure accelerates the circadian clock of cyanobacteria.

Ryo Kitahara, Katsuaki Oyama, Takahiro Kawamura, Keita Mitsuhashi, Soichiro Kitazawa, Kazuhiro Yasunaga, Natsuno Sagara, Megumi Fujimoto, Kazuki Terauchi

Scientific reports, 9(1) 12395-12395, Aug 27, 2019
Gene delivery to cone photoreceptors by subretinal injection of rAAV2/6 in the mouse retina.

Tesshu Hori, Masashi Fukutome, Chiseto Maejima, Hiroki Matsushima, Kensuke Kobayashi, Soichiro Kitazawa, Ryo Kitahara, Katsunori Kitano, Kenta Kobayashi, Satoru Moritoh …

Biochemical and biophysical research communications, 515(1) 222-227, Jul 12, 2019 Peer-reviewed
Water-Protein Interactions Coupled with Protein Conformational Transition.

Kitazawa S, Aoshima Y, Wakamoto T, Kitahara R

Biophys J, 18(115) 981-987, Sep, 2018
Interactions Controlling the Slow Dynamic Conformational Motions of Ubiquitin

Soichiro Kitazawa, Maho Yagi-Utsumi, Koichi Kato, Ryo Kitahara

MOLECULES, 22(9) E1414, Sep, 2017
Analysis of O-2-binding Sites in Proteins Using Gas-Pressure NMR Spectroscopy: Outer Surface Protein A

Takahiro Kawamura, Takuro Wakamoto, Soichiro Kitazawa, Shun Sakuraba, Tomoshi Kameda, Ryo Kitahara

BIOPHYSICAL JOURNAL, 112(9) 1820-1828, May, 2017 Peer-reviewed
NMR and Computation Reveal a Pressure-Sensitive Folded Conformation of Trp-Cage

Soichiro Kitazawa, Martin J. Fossat, Scott A. McCallum, Angel E. Garcia, Catherine A. Royer

JOURNAL OF PHYSICAL CHEMISTRY B, 121(6) 1258-1267, Feb, 2017
High Pressure ZZ-Exchange NMR Reveals Key Features of Protein Folding Transition States

Yi Zhang, Soichiro Kitazawa, Ivan Peran, Natalie Stenzoski, Scott A. McCallum, Daniel P. Raleigh, Catherine A. Royer

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 138(46) 15260-15266, Nov, 2016
Zinc Ion-binding Activity of an Anti-ZnO VHH Antibody, 4F2

Ryosuke Sasaki, Soichiro Kitazawa, Ryo Kitahara, Hikaru Nakazawa, Yoshikazu Tanaka, Izumi Kumagai, Mitsuo Umetsu, Koki Makabe

CHEMISTRY LETTERS, 44(10) 1309-1311, Oct, 2015 Peer-reviewed
Close identity between alternatively folded state N2 of ubiquitin and the conformation of the protein bound to the ubiquitin-activating enzyme.

Kitazawa S, Kameda T, Kumo A, Yagi-Utsumi M, Baxter NJ, Kato K, Williamson MP, Kitahara R

Biochemistry, 53(3) 447-449, Jan, 2014 Peer-reviewed
Pressure-Induced Misfolding of RNA Recognition Motinf1 of TDP-43

KITAHARA Ryo, KITAZAWA Soichiro, URUSHITANI Makoto

Seibutsu Butsuri, 53(6) 321-322, Nov 25, 2013
Aberrant Assembly of RNA Recognition Motif 1 Links to Pathogenic Conversion of TAR DNA-binding Protein of 43 kDa (TDP-43)

Akemi Shodai, Toshifumi Morimura, Akemi Ido, Tsukasa Uchida, Takashi Ayaki, Rina Takahashi, Soichiro Kitazawa, Sakura Suzuki, Mikako Shirouzu, Takanori Kigawa …

JOURNAL OF BIOLOGICAL CHEMISTRY, 288(21) 14886-14905, May, 2013 Peer-reviewed
Solvent environments significantly affect the enzymatic function of Escherichia coli dihydrofolate reductase: Comparison of wild-type protein and active-site mutant D27E

Eiji Ohmae, Yurina Miyashita, Shin-Ichi Tate, Kunihiko Gekko, Soichiro Kitazawa, Ryo Kitahara, Kunihiro Kuwajima

Biochimica et Biophysica Acta - Proteins and Proteomics, 1834(12) 2782-2794, 2013
2P008 Solution structure of the "pure" high-energy state of ubiquitin: Q41N at 2.5 kbar(01A. Protein: Structure,Poster)

Kumo Ayumi, Kitazawa Soichiro, Kameda Tomoshi, Baxter Nicola J., Williamson Michael P., Kitahara Ryo

Seibutsu Butsuri, 53(1) S160, 2013
2P037 Misfolding triggers a pathogenic conversion of protein conformations(01B. Protein: Structure & Function,Poster)

Kitazawa Soichiro, Kitahara Ryo, Urushitani Makoto

Seibutsu Butsuri, 53(1) S165, 2013
Solution structure of the Q41N variant of ubiquitin as a model for the alternatively folded state N2 of ubiquitin

S.Kitazawa, T.Kameda, M.Yagi-Utsumi, K.Sugase, N.J.Baxter, K.Kato, M.P. Williamson, R.Kitahara

Biochemistry, 52(11) 1874-1885, 2013
1PT112 Solution stucture of the alternatively folded state of ubiquitin(The 50th Annual Meeting of the Biophysical Society of Japan)

Kitazawa Soichiro, Kameda Tomoshi, Yagi Maho, Sugase Kenji, Baxter Nicky, Kato Koichi, Williamson Michael P., Kitahara Ryo

Seibutsu Butsuri, 52 S87, 2012

Misc.

Design Strategy for High Free-Energy States of Proteins Based on High-Pressure NMR Study: Alternatively Folded Conformation of Ubiquitin

Ryo Kitahara, Soichiro Kitazawa, Maho Yagi-Utsumi, Akemi Ido, Makoto Urushitani, Kenji Sugase, Koichi Kato

BIOPHYSICAL JOURNAL, 102(3) 25A-25A, Jan, 2012

Presentations

Conformational fluctuation and stability of major and minor form of phosphorylated ubiquitin by high pressure NMR.

第57回NMR討論会, Sep 18, 2018
High-pressure NMR reveals water-protein interactions coupled with protein conformational transition

XXVIII international conference on magnetic resonance in biological systems, Aug 19, 2018
リン酸化ユビキチンの2つのコンフォメーションの立体構造決定と圧力効果

第５６回NMR討論会, Nov 14, 2017
高圧力NMR法によるユビキチンの局所変性状態の立体構造決定

第５６回NMR討論会, Nov 14, 2017
Conformational fluctuation of phosphorylated-ubiquitin studied by high-pressure NMR spectroscopy

第５５回日本生物物理学会年会, Sep 21, 2017
High pressure NMR study of phospho ubiquitin and phospho-mimic mutant ubiquitin

第17回日本蛋白質科学会, Jun 21, 2017
高圧力 NMR 法によるユビキチンの局所変性状態の立体構造解析

第１７回日本蛋白質科学会, Jun 21, 2017
Structure of the Alternative State of Ubiquitin determined by High-pressure NMR spectroscopy

The XXXVII International Conference on Magnetic Resonance in Biological Systems, Aug 24, 2016

Teaching Experience

Professional Memberships

The Nuclear Magnetic resonance society of japan

Research Projects

Structure determination and pressure effects of major and minor conformations of phosphorylated ubiquitin

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2021

Kitazawa Soichiro

Profile Information

Research Interests

Research Areas

Research History

Education

Papers

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Presentations

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