NOMOTO Takahiro

J-GLOBAL         Last updated: Dec 5, 2019 at 11:55
 
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Name
NOMOTO Takahiro
Affiliation
Tokyo Institute of Technology
Section
Research Institute of Science and Technology
Job title
Assistant Professor
Research funding number
00734732
ORCID ID
0000-0002-0391-0478

Research Areas

 
 

Academic & Professional Experience

 
Apr 2016
 - 
Today
Assistant professor, Institute of Innovative Research, Tokyo Institute of Technology
 
Apr 2014
 - 
Mar 2016
Assistant professor, Chemical Resources Laboratory, Tokyo Institute of Technology
 
Apr 2011
 - 
Mar 2014
Research Fellowship for Young Scientists, Department of Bioengineering, School of Engineering, The University of Tokyo
 

Education

 
Apr 2009
 - 
Mar 2014
Department of Bioengineering, School of Engineering, The University of Tokyo
 
Apr 2007
 - 
Mar 2009
Material Engineering, Department of Engineering, The University of Tokyo
 

Awards & Honors

 
2017
Outstanding reviewer, Elsevier Biomaterials
 

Published Papers

 
Takemoto Hiroyasu, Wang Chih-Ling, Nomoto Takahiro, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
BIOMACROMOLECULES   20(6) 2305-2314   Jun 2019   [Refereed]
Watanabe Sumiyo, Hayashi Kotaro, Toh Kazuko, Kim Hyun Jin, Liu Xueying, Chaya Hiroyuki, Fukushima Shigeto, Katsushima Keisuke, Kondo Yutaka, Uchida Satoshi, Ogura Satomi, Nomoto Takahiro, Takemoto Hiroyasu, Cabral Horacio, Kinoh Hiroaki, Tanaka Hiroyoshi Y., Kano Mitsunobu R., Matsumoto Yu, Fukuhara Hiroshi, Uchida Shunya, Nangaku Masaomi, Osada Kensuke, Nishiyama Nobuhiro, Miyata Kanjiro, Kataoka Kazunori
NATURE COMMUNICATIONS   10    Apr 2019   [Refereed]
El Muttaqien Sjaikhurrizal, Nomoto Takahiro, Takemoto Hiroyasu, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
BIOMACROMOLECULES   20(4) 1493-1504   Apr 2019   [Refereed]
Metabolism-controlled boron delivery systems composed of biocompatible polymers and boronophenylalanine for neutron capture therapy
Nomoto Takahiro, Inoue Yukiya, Yao Ying, Suzuki Minoru, Kanamori Kaito, Takemoto Hiroyasu, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   257    Mar 2019   [Refereed]
Chida Tsukasa, Miura Yutaka, Cabral Horacio, Nomoto Takahiro, Kataoka Kazunori, Nishiyama Nobuhiro
JOURNAL OF CONTROLLED RELEASE   292 130-140   Dec 2018   [Refereed]
Nomoto Takahiro, Nishiyama Nobuhiro
BIOMATERIALS   178 583-596   Sep 2018   [Refereed]
Ethylenediamine-based betaine structure switches the neutral net charge of polyzwitterion into cationic at tumorous pH toward effective tumor accumulation of the coated nanomaterials
Takemoto Hiroyasu, Ranneh Abdul-Hackam, Nomoto Takahiro, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   256    Aug 2018   [Refereed]
Novel design of pH-responsive polymer for targeting acidic microenvironment of tumor
El Muttaqien Sjaikhurrizal, Nomoto Takahiro, Takemoto Hiroyasu, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   256    Aug 2018   [Refereed]
Dou Xuebo, Nomoto Takahiro, Takemoto Hiroyasu, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
SCIENTIFIC REPORTS   8    May 2018   [Refereed]
Ranneh Abdul-Hackam, Takemoto Hiroyasu, Sakuma Shunya, Awaad Aziz, Nomoto Takahiro, Mochida Yuki, Matsui Makoto, Tomoda Keishiro, Naito Mitsuru, Nishiyama Nobuhiro
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   57(18) 5057-5061   Apr 2018   [Refereed]
Yamada Naoki, Honda Yuto, Takemoto Hiroyasu, Nomoto Takahiro, Matsui Makoto, Tomoda Keishiro, Konno Masamitsu, Ishii Hideshi, Mori Masaki, Nishiyama Nobuhiro
SCIENTIFIC REPORTS   7    Jul 2017   [Refereed]
Novel design of glutamine-derived polymer with a high affinity to cancer cells based on aberrant glutamine metabolism
Honda Yuto, Yamada Naoki, Takemoto Hiroyasu, Nomoto Takahiro, Matsui Makoto, Tomoda Keishiro, Nishiyama Nobuhiro
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   253    Apr 2017   [Refereed]
2-Nitrobenzenesulfonamide group as a chemical linker with highly selective cleavability in response to intracellular redox system for a construction of siRNA-polymer conjugate
Takemoto Hiroyasu, Huang Chih-Hao, Nomoto Takahiro, Tomoda Keishiro, Matsui Makoto, Nishiyama Nobuhiro
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   253    Apr 2017   [Refereed]
Huang Chih Hao, Takemoto Hiroyasu, Nomoto Takahiro, Tomoda Keishiro, Matsui Makoto, Nishiyama Nobuhiro
CHEMMEDCHEM   12(1) 19-22   Jan 2017   [Refereed]
Chen Qixian, Osada Kensuke, Ge Zhishen, Uchida Satoshi, Tockary Theofilus A., Dirisala Anjaneyulu, Matsui Akitsugu, Toh Kazuko, Takeda Kaori M., Liu Xueying, Nomoto Takahiro, Ishii Tekihiko, Oba Makoto, Matsumoto Yu, Kataoka Kazunori
BIOMATERIALS   113 253-265   Jan 2017   [Refereed]
Harun Noor Faizah Che, Takemoto Hiroyasu, Nomoto Takahiro, Tomoda Keishiro, Matsui Makoto, Nishiyama Nobuhiro
BIOCONJUGATE CHEMISTRY   27(9) 1961-1964   Sep 2016   [Refereed]
Matsumoto Yu, Nichols Joseph W., Toh Kazuko, Nomoto Takahiro, Cabral Horacio, Miura Yutaka, Christie R. James, Yamada Naoki, Ogura Tadayoshi, Kano Mitsunobu R., Matsumura Yasuhiro, Nishiyama Nobuhiro, Yamasoba Tatsuya, Bae You Han, Kataoka Kazunori
NATURE NANOTECHNOLOGY   11(6) 533-+   Jun 2016   [Refereed]
Anraku Yasutaka, Kishimura Akihiro, Kamiya Mako, Tanaka Sayaka, Nomoto Takahiro, Toh Kazuko, Matsumoto Yu, Fukushima Shigeto, Sueyoshi Daiki, Kano Mitsunobu R., Urano Yasuteru, Nishiyama Nobuhiro, Kataoka Kazunori
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION   55(2) 560-565   Jan 2016   [Refereed]
Nomoto Takahiro, Fukushima Shigeto, Kumagai Michiaki, Miyazaki Kozo, Inoue Aki, Mi Peng, Maeda Yoshinori, Toh Kazuko, Matsumoto Yu, Morimoto Yuji, Kishimura Akihiro, Nishiyama Nobuhiro, Kataoka Kazunori
BIOMATERIALS SCIENCE   4(5) 826-838   2016   [Refereed]
Kawamura Wataru, Miura Yutaka, Kokuryo Daisuke, Toh Kazuko, Yamada Naoki, Nomoto Takahiro, Matsumoto Yu, Sueyoshi Daiki, Liu Xueying, Aoki Ichio, Kano Mitsunobu R., Nishiyama Nobuhiro, Saga Tsuneo, Kishimura Akihiro, Kataoka Kazunori
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS   16(3)    Jun 2015   [Refereed]
Cabral Horacio, Makino Jun, Matsumoto Yu, Mi Peng, Wu Hailiang, Nomoto Takahiro, Toh Kazuko, Yamada Naoki, Higuchi Yuriko, Konishi Satoshi, Kano Mitsunobu R., Nishihara Hiroshi, Miura Yutaka, Nishiyama Nobuhiro, Kataoka Kazunori
ACS NANO   9(5) 4957-4967   May 2015   [Refereed]
Uchida Hirokuni, Itaka Keiji, Nomoto Takahiro, Ishii Takehiko, Suma Tomoya, Ikegami Masaru, Miyata Kanjiro, Oba Makoto, Nishiyama Nobuhiro, Kataoka Kazunori
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   136(35) 12396-12405   Sep 2014   [Refereed]
Toolbox of differently sized and labeled PMMA nanoparticles for cell studies
Schubert Stephanie, Vollrath Antje, Traeger Anja, Pretzel David, Pietsch Christian, Nomoto Takahiro, Matsumoto Yu, Kataoka Kazunori, Schubert Ulrich S.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   248    Aug 2014   [Refereed]
Maeda Yoshinori, Pittella Frederico, Nomoto Takahiro, Takemoto Hiroyasu, Nishiyama Nobuhiro, Miyata Kanjiro, Kataoka Kazunori
MACROMOLECULAR RAPID COMMUNICATIONS   35(13) 1211-1215   Jul 2014   [Refereed]
Kim Hyun Jin, Miyata Kanjiro, Nomoto Takahiro, Zheng Meng, Kim Ahram, Liu Xueying, Cabral Horacio, Christie R. James, Nishiyama Nobuhiro, Kataoka Kazunori
BIOMATERIALS   35(15) 4548-4556   May 2014   [Refereed]
Nomoto Takahiro, Fukushima Shigeto, Kumagai Michiaki, Machitani Kaori, Arnida, Matsumoto Yu, Oba Makoto, Miyata Kanjiro, Osada Kensuke, Nishiyama Nobuhiro, Kataoka Kazunori
NATURE COMMUNICATIONS   5    Apr 2014   [Refereed]
Uchida Satoshi, Itaka Keiji, Nomoto Takahiro, Endo Taisuke, Matsumoto Yu, Ishii Takehiko, Kataoka Kazunori
BIOMATERIALS   35(8) 2499-2506   Mar 2014   [Refereed]
Ge Zhishen, Chen Qixian, Osada Kensuke, Liu Xueying, Tockary Theofilus A., Uchida Satoshi, Dirisala Anjaneyulu, Ishii Takehiko, Nomoto Takahiro, Toh Kazuko, Matsumoto Yu, Oba Makoto, Kano Mitsunobu R., Itaka Keiji, Kataoka Kazunori
BIOMATERIALS   35(10) 3416-3426   Mar 2014   [Refereed]
Synatschke Christopher V., Nomoto Takahiro, Cabral Horacio, Foertsch Melanie, Toh Kazuko, Matsumoto Yu, Miyazaki Kozo, Hanisch Andreas, Schacher Felix H., Kishimura Akihiro, Nishiyama Nobuhiro, Mueller Axel H. E., Kataoka Kazunori
ACS NANO   8(2) 1161-1172   Feb 2014   [Refereed]
Mi Peng, Kokuryo Daisuke, Cabral Horacio, Kumagai Michiaki, Nomoto Takahiro, Aoki Ichio, Terada Yasuko, Kishimura Akihiro, Nishiyama Nobuhiro, Kataoka Kazunori
JOURNAL OF CONTROLLED RELEASE   174 63-71   Jan 2014   [Refereed]
Chen Huabing, Xiao Ling, Anraku Yasutaka, Mi Peng, Liu Xueying, Cabral Horacio, Inoue Aki, Nomoto Takahiro, Kishimura Akihiro, Nishiyama Nobuhiro, Kataoka Kazunori
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   136(1) 157-163   Jan 2014   [Refereed]
Miura Yutaka, Takenaka Tomoya, Toh Kazuko, Wu Shourong, Nishihara Hiroshi, Kano Mitsunobu R., Ino Yasushi, Nomoto Takahiro, Matsumoto Yu, Koyama Hiroyuki, Cabral Horacio, Nishiyama Nobuhiro, Kataoka Kazunori
ACS NANO   7(10) 8583-8592   Oct 2013   [Refereed]
Kusumoto Kenji, Akita Hidetaka, Ishitsuka Taichi, Matsumoto Yu, Nomoto Takahiro, Furukawa Ryo, El-Sayed Ayman, Hatakeyama Hiroto, Kajimoto Kazuaki, Yamada Yuma, Kataoka Kazunori, Harashima Hideyoshi
ACS NANO   7(9) 7534-7541   Sep 2013   [Refereed]
Tockary Theofilus A., Osada Kensuke, Chen Qixian, Machitani Kaori, Dirisala Anjaneyulu, Uchida Satoshi, Nomoto Takahiro, Toh Kazuko, Matsumoto Yu, Itaka Keiji, Nitta Koji, Nagayama Kuniaki, Kataoka Kazunori
MACROMOLECULES   46(16) 6585-6592   Aug 2013   [Refereed]
Gouda Noha, Miyata Kanjiro, Christie R. James, Suma Tomoya, Kishimura Akihiro, Fukushima Shigeto, Nomoto Takahiro, Liu Xueying, Nishiyama Nobuhiro, Kataoka Kazunori
BIOMATERIALS   34(2) 562-570   Jan 2013   [Refereed]
Vollrath Antje, Schallon Anja, Pietsch Christian, Schubert Stephanie, Nomoto Takahiro, Matsumoto Yu, Kataoka Kazunori, Schubert Ulrich S.
SOFT MATTER   9(1) 99-108   2013   [Refereed]
Nomoto Takahiro, Matsumoto Yu, Toh Kazuko, Christie R. James, Miyata Kanjiro, Oba Makoto, Cabral Horacio, Murakami Mami, Fukushima Shigeto, Nishiyama Nobuhiro, Kataoka Kazunori
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN   132(12) 1347-1354   Dec 2012   [Refereed]
Towards multifunctional drug delivery systems from ionic triblock terpolymer micelles
Synatschke Christopher V., Nomoto Takahiro, Kishimura Akihiro, Muller Axel H. E., Kataoka Kazunori
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   244    Aug 2012   [Refereed]
Christie R. James, Matsumoto Yu, Miyata Kanjiro, Nomoto Takahiro, Fukushima Shigeto, Osada Kensuke, Halnaut Julien, Pittella Frederico, Kim Hyun Jin, Nishiyama Nobuhiro, Kataoka Kazunori
ACS NANO   6(6) 5174-5189   Jun 2012   [Refereed]
Miyazaki Kozo, Morimoto Yuji, Hiruma Hitomi, Inoue Aki, Nomoto Takahiro, Fukushima Shigeto, Iwaya Keiichi, Shinomiya Nariyoshi, Nishiyama Nobuhiro, Kataoka Kazunori
CANCER RESEARCH   72    Apr 2012   [Refereed]
Hiruma Hitomi, Morimoto Yuji, Miyazaki Kozo, Inoue Aki, Nomoto Takahiro, Hukushima Shigeto, Shinomioya Nariyoshi, Nishiyama Nobuhiro, Kataoka Kazunori
CANCER RESEARCH   72    Apr 2012   [Refereed]
Targeted polymeric micelles for small interfering ribonucleic acid delivery
Christie R. James, Matsumoto Yu, Miyata Kanjiro, Nomoto Takahiro, Fukushima Shigeto, Kim Hyun Jin, Pitella Frederico, Nishiyama Nobuhiro, Kataoka Kazunori
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   243    Mar 2012   [Refereed]
Kim Hyun Jin, Oba Makoto, Pittella Frederico, Nomoto Takahiro, Cabral Horacio, Matsumoto Yu, Miyata Kanjiro, Nishiyama Nobuhiro, Kataoka Kazunori
JOURNAL OF DRUG TARGETING   20(1) 33-42   Jan 2012   [Refereed]
Herlambang Stephanie, Kumagai Michiaki, Nomoto Takahiro, Horie Souta, Fukushima Shigeto, Oba Makoto, Miyazaki Kozo, Morimoto Yuji, Nishiyama Nobuhiro, Kataoka Kazunori
JOURNAL OF CONTROLLED RELEASE   155(3) 449-457   Nov 2011   [Refereed]
Christie R. James, Miyata Kanjiro, Matsumoto Yu, Nomoto Takahiro, Menasco Daniel, Lai Tzai Chung, Pennisi Matthew, Osada Kensuke, Fukushima Shigeto, Nishiyama Nobuhiro, Yamasaki Yuichi, Kataoka Kazunori
BIOMACROMOLECULES   12(9) 3174-3185   Sep 2011   [Refereed]
Nomoto Takahiro, Matsumoto Yu, Miyata Kanjiro, Oba Makoto, Fukushima Shigeto, Nishiyama Nobuhiro, Yamasoba Tatsuya, Kataoka Kazunori
JOURNAL OF CONTROLLED RELEASE   151(2) 104-109   Apr 2011   [Refereed]
Matsumoto Yu, Nomoto Takahiro, Cabral Horacio, Matsumoto Yoko, Watanabe Sumiyo, Christie R. James, Miyata Kanjiro, Oba Makoto, Ogura Tadayoshi, Yamasaki Yuichi, Nishiyama Nobuhiro, Yamasoba Tatsuya, Kataoka Kazunori
BIOMEDICAL OPTICS EXPRESS   1(4) 1209-1216   Nov 2010   [Refereed]
Development of advanced polymer-based nanodevices for nucleic acids delivery
Miyata Kanjiro, Nomoto Takahiro, Takemoto Hiroyasu, Kim Hyun Jin, Matsumoto Yu, Oba Makoto, Nishiyama Nobuhiro, Kataoka Kazunori
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY   240    Aug 2010   [Refereed]

Misc

 
【光で操るバイオマテリアル】光増感剤デリバリーを指向したバイオマテリアルの設計
野本 貴大, 西山 伸宏
バイオマテリアル-生体材料-   37(3) 188-193   Jul 2019
光線力学療法は超低侵襲的に腫瘍を治療する方法として注目されており、光増感剤をいかに選択的に腫瘍に送達できるかが重要である。しかし、光増感剤デリバリーは、制がん剤などのデリバリーとは異なる課題を有しており、それに対する独特なアプローチが求められる。本稿では、光増感剤デリバリーを指向した最近の我々のバイオマテリアル設計の成果について紹介する。(著者抄録)
腫瘍pH応答性高分子ベタインの開発とナノ粒子のがん送達への展開
武元 宏泰, アワード・アジズ, 野本 貴大, 松井 誠, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   35回 127-127   Jun 2019
薬物送達技術を応用した新規骨折治療法の開発
松井 誠, 海原 悠可, 武元 宏泰, 野本 貴大, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   35回 128-128   Jun 2019
ボロン酸エステルを利用したホウ素薬物送達キャリアの開発
金盛 開人, 野本 貴大, 鈴木 実, 武元 宏泰, 松井 誠, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   35回 128-128   Jun 2019
がん治療を指向した生体内鉄イオンをキレートする機能性高分子の開発
河本 花奈, 野本 貴大, 武元 宏泰, 松井 誠, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   35回 129-129   Jun 2019
温度応答性高分子-siRNA結合体とのポリイオンコンプレックス形成と外部刺激によるsiRNAの薬効制御
小野寺 彩, 武元 宏泰, 野本 貴大, 友田 敬士郎, 松井 誠, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   35回 183-183   Jun 2019
がん幹細胞を標的とするポリエチレングリコール修飾スルファサラジンの開発および機能評価
谷脇 香, 山田 直生, 武元 宏泰, 椎名 健太郎, 野本 貴大, 松井 誠, 永野 修, 佐谷 秀行, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   35回 188-188   Jun 2019
Tumor-targeted delivery of BPA using functional polymers for boron neutron capture therapy(和訳中)
Ying Yao, 野本 貴大, 井上 透矢, 鈴木 実, 松井 誠, 武元 宏泰, 友田 敬士郎, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   34回 147-147   May 2018
IRDye 700DXの腫瘍内分布を制御する環状RGD担持高分子コンジュゲートによる光線力学効果の検討
野本 貴大, Dou Xuebo, 武元 宏泰, 松井 誠, 友田 敬士郎, 西山 伸宏
日本DDS学会学術集会プログラム予稿集   34回 148-148   May 2018
効率的な光線力学療法を指向したハイブリッド型光増感剤送達システム
野本 貴大, 福島 重人, 熊谷 康顕, 宮崎 幸造, 井上 明季, Mi Peng, 前田 芳周, 籐 加珠子, 松本 有, 守本 祐司, 岸村 顕広, 西山 伸宏, 片岡 一則
日本薬学会年会要旨集   138年会(4) 149-149   Mar 2018

Books etc

 
Photochemistry for Biomedical Applications
NOMOTO Takahiro (Part:Contributor, Photodynamic therapy)
Springer Nature   2018   
Cancer targeted drug delivery
NOMOTO Takahiro (Part:Contributor, Intravital real-time confocal laser scanning microscopy for the in situ evaluation of nanocarriers)
Springer   2013   

Research Grants & Projects

 
Development of smart polymeric micelles based on novel shell and core designs
JSPS: KAKENHI
Project Year: 2018 - 2022    Investigator(s): NISHIYAMA Nobuhiro
JSPS: KAKENHI
Project Year: 2018 - 2020    Investigator(s): NOMOTO Takahiro
JSPS: KAKENHI
Project Year: 2017 - 2020    Investigator(s): MORIMOTO Yuji
JST: COI fund for young researchers
Project Year: 2018 - 2019    Investigator(s): NOMOTO Takahiro
JSPS: KAKENHI
Project Year: 2015 - 2018    Investigator(s): NISHIYAMA Nobuhiro
Tokyo Institute of Technology: Planting Seeds for Research Program
Project Year: 2015 - 2016    Investigator(s): NOMOTO Takahiro
JSPS: KAKENHI
Project Year: 2014 - 2016    Investigator(s): NOMOTO Takahiro
JSPS: Grant-in-Aid for JSPS Research Fellow
Project Year: 2011 - 2014    Investigator(s): NOMOTO Takahiro