Meiko Kawamura

Profile Information

Affiliation: Specially Appointed Assistant Professor, Brain Research Institute Basic Neuroscience Branch, Niigata University
: 非常勤講師, 新潟青陵大学

Degree: 博士（医学）(京都大学)

Contact information: meikocc.niigata-u.ac.jp
Researcher number: 20377196
J-GLOBAL ID: 201601020454697132
researchmap Member ID: 7000018365

External link: http://www.niigata-u.ac.jp/business/ccrf/ccrf-analysis/

Research Interests

Research Areas

Life sciences / Medical biochemistry /

Research History

Apr, 2023 - Present

Project Assistant Professor, Center for Coordination of Research Facilities, Division of Instrumental Analysis, Niigata University, Institute for Research Administration
Apr, 2001 - Present

Niigata Seiryo University
Apr, 2015 - Mar, 2023

Specially Appointed Assistant Professor, Brain Research Institute Basic Neuroscience Branch, Niigata University

Education

Apr, 1983 - Mar, 1985

Department of Epizootiology, Graduate School, Division of Veterinary Medicine, Hokkaido University
Apr, 1979 - Mar, 1983

Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University

Papers

Pathogenesis, Clinical Features, and Treatment of Patients with Myelin Oligodendrocyte Glycoprotein (MOG) Autoantibody-Associated Disorders Focusing on Optic Neuritis with Consideration of Autoantibody-Binding Sites: A Review

Keiko Tanaka, Takeshi Kezuka, Hitoshi Ishikawa, Masami Tanaka, Kenji Sakimura, Manabu Abe, Meiko Kawamura

International Journal of Molecular Sciences, 24(17) 13368-13368, Aug 29, 2023 Peer-reviewed
Vasopressin Expressed in Hypothalamic CRF Neurons Causes Impaired Water Diuresis in Secondary Adrenal Insufficiency

Satoshi Yamagata, Ashraf H Talukder, Shingo Murasawa, Kanako Niioka, Naoya Kumagai, Mao Takagi, Meiko Kawamura, Rie Natsume, Manabu Abe, Katsuya Uchida …

Endocrinology, 164(8), Jun 26, 2023 Peer-reviewed
Activity-induced secretion of semaphorin 3A mediates learning.

Aoi Jitsuki-Takahashi, Susumu Jitsuki, Naoya Yamashita, Meiko Kawamura, Manabu Abe, Kenji Sakimura, Akane Sano, Fumio Nakamura, Yoshio Goshima, Takuya Takahashi

The European journal of neuroscience, 53(10) 3279-3293, May, 2021 Peer-reviewed
Central dopamine D2 receptors regulate plasma glucose levels in mice through autonomic nerves

Hiroko Ikeda, Naomi Yonemochi, Risa Mikami, Manabu Abe, Meiko Kawamura, Rie Natsume, Kenji Sakimura, John L. Waddington, Junzo Kamei

Scientific Reports, 10(1), Dec, 2020 Peer-reviewed
Significance of Autoantibodies in Autoimmune Encephalitis in Relation to Antigen Localization: An Outline of Frequently Reported Autoantibodies with a Non-Systematic Review.

Keiko Tanaka, Meiko Kawamura, Kenji Sakimura, Nobuo Kato

International journal of molecular sciences, 21(14), Jul 13, 2020 Peer-reviewed
Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain.

Chihiro Nakamoto, Kohtarou Konno, Taisuke Miyazaki, Ena Nakatsukasa, Rie Natsume, Manabu Abe, Meiko Kawamura, Yugo Fukazawa, Ryuichi Shigemoto, Miwako Yamasaki …

The Journal of comparative neurology, 528(6) 1003-1027, Apr, 2020 Peer-reviewed
GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.

Chihiro Nakamoto, Meiko Kawamura, Ena Nakatsukasa, Rie Natsume, Keizo Takao, Masahiko Watanabe, Manabu Abe, Tomonori Takeuchi, Kenji Sakimura

PloS one, 15(2) e0229288, 2020 Peer-reviewed
Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice.

Srikanta Chowdhury, Chi Jung Hung, Shuntaro Izawa, Ayumu Inutsuka, Meiko Kawamura, Takashi Kawashima, Haruhiko Bito, Itaru Imayoshi, Manabu Abe, Kenji Sakimura …

eLife, 8, Jun 4, 2019 Peer-reviewed
Autophosphorylation of F-actin binding domain of CaMKIIβ is required for fear learning.

Karam Kim, Akio Suzuki, Hiroto Kojima, Meiko Kawamura, Ken Miya, Manabu Abe, Ikuko Yamada, Tamio Furuse, Shigenaru Wakana, Kenji Sakimura …

Neurobiology of learning and memory, 157 86-95, Jan, 2019 Peer-reviewed
Higher visual responses in the temporal cortex of mice

Nishino K, Tsukano H, Hishida R, Abe M, Nakai J, Kawamura M, Aiba A, Sakimura K, Shibuki K

Scientific reports, 2018 Peer-reviewed
GLUD1 deficient mouse as a model animal of depressionlike behavior

K. Sakimura, C. Nakamoto, M. Abe, M. Kawamura, H. Uchida, M. Watanabe, M. Kano

JOURNAL OF NEUROCHEMISTRY, 142 203-203, Aug, 2017
Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum

Myeongjeong Choo, Taisuke Miyazaki, Maya Yamazaki, Meiko Kawamura, Takanobu Nakazawa, Jianling Zhang, Asami Tanimura, Naofumi Uesaka, Masahiko Watanabe, Kenji Sakimura …

NATURE COMMUNICATIONS, 8(195), Aug, 2017 Peer-reviewed
The cellular and behavioral consequences of interleukin-1 alpha penetration through the blood-brain barrier of neonatal rats: A critical period for efficacy

M. Tohmi, N. Tsuda, Y. Zheng, M. Mizuno, H. Sotoyama, M. Shibuya, M. Kawamura, A. Kakita, H. Takahashi, H. Nawa

NEUROSCIENCE, 150(1) 234-250, Nov, 2007 Peer-reviewed
Association of 14-3-3 epsilon gene haplotype with completed suicide in Japanese

M Yanagi, O Shirakawa, N Kitamura, K Okamura, K Sakurai, N Nishiguchi, T Hashimoto, H Nushida, Y Ueno, D Kanbe …

JOURNAL OF HUMAN GENETICS, 50(4) 210-216, Apr, 2005 Peer-reviewed
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites

Takei N, Inamura N, Kawamura M, Namba H, Hara K, Yonezawa K, Nawa H

JOURNAL OF NEUROSCIENCE, 24(44) 9760-9769, Nov 3, 2004 Peer-reviewed
Prefrontal abnormality of schizophrenia revealed by DNA microarray - Impact on glial and neurotrophic gene expression

Sugai T, Kawamura M, Iritani S, Araki K, Makifuchi T, Imai C, Nakamura R, Kakita A, Takahashi H, Nawa H

CURRENT STATUS OF DRUG DEPENDENCE / ABUSE STUDIES: CELLULAR AND MOLECULAR MECHANISMS OF DRUGS OF ABUSE AND NEUROTOXICITY, 1025 84-91, 2004 Peer-reviewed
Prefrontal abnormality of schizophrenia revealed by DNA microarray: Impact on glial and neurotrophic gene expression

Tetsuji Sugai, Meiko Kawamura, Shuji Iritani, Kazuaki Araki, Takao Makifuchi, China Imai, Ryosuke Nakamura, Akiyoshi Kakita, Hitoshi Takahashi, Hiroyuki Nawa

Annals of the New York Academy of Sciences, 1025 84-91, 2004 Peer-reviewed
A palmitoylated RING finger ubiquitin ligase and its homologue in the brain membranes

K Araki, M Kawamura, T Suzuki, N Matsuda, D Kanbe, K Ishii, T Ichikawa, T Kumanishi, T Chiba, K Tanaka …

JOURNAL OF NEUROCHEMISTRY, 86(3) 749-762, Aug, 2003 Peer-reviewed
Characterization of novel bicistronic Sindbis virus vectors, SinEGdsp and SinIRES-EG, in cultured neurons. (Minireview)

Kawamura M, Namba H, Otsu Y, Hayashi Y, Takei N. Nawa H

Recent Research Development in Neurochemistry, 2003
Brain-derived neurotrophic factor regulates surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid receptors by enhancing the N-ethylmaleimide-sensitive factor/GluR2 interaction in developing neocortical neurons

M Narisawa-Saito, Y Iwakura, M Kawamura, K Araki, S Kozaki, N Takei, H Nawa

JOURNAL OF BIOLOGICAL CHEMISTRY, 277(43) 40901-40910, Oct, 2002 Peer-reviewed

Misc.

抗体介在性自己免疫性脳炎と精神医学自己免疫性脳炎・脳症の広がりとその背景要因に関する考察

田中惠子, 渡邊ユリ, 阿部学, 崎村建司, 川村名子

精神神経学雑誌, 124(4付録) S-447, Apr, 2022
抗体介在性自己免疫性脳炎と精神疾患自己免疫病態による精神疾患と認知症

田中惠子, 川村名子, 筒井幸, 崎村建司, 阿部学

精神神経学雑誌, (2021特別号) S294-S294, Sep, 2021
自己免疫性脳炎関連自己抗体の網羅的検出系作成と各種抗体検出頻度

田中惠子, 北川陽子, 堀喜代江, 渡邉ユリ, 崎村建司, 川村名子

神経免疫学, 25(1) 160-160, Oct, 2020
Generation of GATA4-flox mouse by gene targeting method

IWASAKI Tsugumi, MURATA Kousuke, KAWAMURA Meiko, NAKATSUKASA Ena, ABE Manabu, NATSUME Rie, SUGIMURA Satoshi, SAKIMURA Kenji, YAMASHIRO Hideaki

The Journal of Reproduction and Development Supplement, 113 P-11-P-11, 2020
D1/D2ドーパミン受容体コンディショナル発現マウスによる運動制御機構の解明

笹岡俊邦, 佐藤朝子, 知見聡美, 大久保直, 阿部学, 川村名子, 中尾聡宏, 齊藤奈英, 酒井清子, 小田佳奈子 …

生命科学系学会合同年次大会, 2017年度 [4LT08-1195)], Dec, 2017
脳に高発現する膜結合型,新規ユビキチン・ライゲース(Momo及びSakura)の生化学的解析(Ubiquitin ligase activity and palmitoylation of the membrane-associating RING finger proteins, Momo and Sakura)

川村名子, 荒木一明, 鈴木俊顕, 松田憲之, 神辺太樹, 千葉智樹, 田中啓二, 那波宏之

神経化学, 42(2-3) 270-270, Aug, 2003
Enhancement of human immunodeficiency virus type 1 infectivity by Nef is producer cell-dependent.

Tokunaga Kenzo, Kojima Asato, Kurata Takeshi, Ikuta Kazuyoshi, Akari Hirofumi, Koyama Hajime, Kawamura Meiko, Inubushi Ritsuko, Shimano Reika, Adachi Akio

Collected papers from the Institute of Immunological Science Hokkaido University, 21 120-126, 1998
Producer cell-dependent requirement of the Nef protein for efficient entry of HIV-1 into cells.

Tokunaga Kenzo, Kojima Asato, Kurata Takeshi, Ikuta Kazuyoshi, Inubushi Ritsuko, Shimano Reika, Kawamura Meiko, Akari Hirofumi, Koyama A. Hajime, Adachi Akio

Collected papers from the Institute of Immunological Science Hokkaido University, 21 109-112, 1998
HIV複製の分子基盤.

足立昭夫, 川村名子

医学のあゆみ, 176(1) 17-23, 1996
ヒト免疫不全ウイルス (HIV) のアクセサリー遺伝子

川村名子, 徳永研三, 足立昭夫

細胞工学, 1995
ヒト免疫不全ウイルス (HIV) の制御遺伝子の機能

徳永研三, 古田里佳, 川村名子, 足立昭夫

蛋白質核酸酵素, 40(9) p1079-1091, 1995
レトロウイルス

酒井博幸, 川村名子, 足立昭夫

化学工業, 1993
HIVの起源

足立昭夫, 酒井幸博, 川村名子

Mebio, 1993
HIV-1の増殖機構

酒井博幸, 川村名子, 桜木小百合, 桜木淳一, 足立昭夫

Minophagen Medical Review, 1993
ヒト免疫不全ウイルス(HIV) の生物学.

酒井博幸, 川村名子, 桜木小百合, 岩谷靖雅, 足立昭夫

治療, 1993
HIV遺伝子の構造と機能

川村名子, 酒井博幸, 足立昭夫

日本臨床増刊号, 1993
AIDSウイルスーその増殖機構をめぐって

川村名子, 酒井博幸, 足立昭夫

感染症, 1993
HIVの制御遺伝子と遺伝子治療. エイズー基礎から臨床へ

川村名子, 酒井博幸, 足立昭夫

臨床医のための実験医学シリーズ12, 1993

Presentations

Patients with anti-MOG antibody-positive optic neuritis demonstrated characteristic clinical features and certain binding epitope on human MOG extracellular domain

Tanaka K, Kawamura M, Koike N, Oone M, Sakimura K, Kezuka T, Ishikawa H

ECTRIMS, Oct 12, 2018
Progress of genetically modified mice for A3 group

Kawamura Meiko

Coference on Autophagy at Niigata University, Mar 1, 2018 Invited
Exploring the epitopes of anti-MOG antibodies in the patients with inflammatory demyelinating disease presenting various clinical phenotypes

Naoto Koike, Meiko Kawamura, Moe Oono, Kenji Sakimura, Keiko Tanaka

World Congress of Neurology, 2017
デルタ型グルタミン酸受容体サブユニット機能とその量的関連

中本千尋, 川村名子, 夏目里恵, 阿部学, 渡辺雅彦, 崎村建司

日本生物学的神経医学会, 2016
インターロイキン１によるグルタミン酸トランスポーターの発現調節ー脳内炎症におけるグリア細胞の役割を考察する

川村名子

京都大学ウイルス研究所学術セミナー, Dec 6, 2005, 京都大学ウイルス研究所 Invited
インターロイキン１によるグリア細胞の機能的変換

川村名子, 武井延之, 那波ひろゆき

第70回日本インターフェロン・サイトカイン学会, Jun 20, 2005
転写因子NF-kBを介したインターロイキン１によるグリア細胞の機能変化

川村名子, 武井延之, 那波宏之

神経化学会, Aug, 2004
脳に高発現する膜結合型、新規ユビキチンライゲース（Momo及びSakura)の生化学的解析

川村名子, 荒木一明, 鈴木俊顕, 松田憲之, 神辺太樹, 千葉智樹, 田中啓二, 那波宏之

神経化学会, Aug, 2003
神経細胞とグリア細胞で同定されたZnフィンガー／RINGフィンガー含有分子、MomoとSakura

荒木一明, 川村名子, 神辺太樹, 石井京子, 市川富夫, 熊西敏郎, 田中啓二, 武井延之, 那波宏之

神経化学会, Aug, 2003
The surface expression of AMPA receptor is regulated by BDNF through the modulation of NSF-GluR2 interaction.

Narisawa-Saito M, Iwakura Y, Kawamura M, Araki K, Hussam J, Takei N, Nawa H

31st Annual Meeting, Society for Neuroscience, San Diego, CA. USA, Nov 10, 2001
AMPA型グルタミン酸受容体のC末端を介した受容体内在化機構

岩倉百合子, 堀川洋, 茨木京子, 永野忠聖, 川村名子, 武井延之, 那波宏之

神経化学会, Sep, 2001
Sindbis virus-mediated expression of Ca2+-permeable AMPA receptors in CA1 hippocampal neurons and induction of NMDA receptor-independent long-term poteintiation.

Kakegawa W, Okada T, Iino M, Yamada N, Tsuzuki K, Kawamura M, Nawa H, Ozawa S

30th Annual Meeting, Society for Neuroscience, New Orleans, LA. USA, Nov 4, 2000
Sindbis virus vector carrying GFP as a reporter gene: electrophysilogical and cell biological evaluation in the neocortical neuron.

Namba H, Kawamura M, Okada M, Otsu Y, Nawa H

29th Annual Meeting, Society for Neuroscience, Miami Beach, FL. USA, Oct 23, 1999
RNAウイルスベクターを用いた中枢神経細胞への遺伝子導入

難波寿明, 川村名子, 岡田誠剛, 大津洋, 那波宏之

日本神経科学大会, Jul, 1999
Functional analysis of HIV-1 gag proteins

Kawamura, M, Kitamura, T, Ishimoto, A, Adachi, A

10th International Conference on AIDS Yokohama, Japan., Aug 7, 1994
Production of chimeric virus-like particles containing the HIV-1 gag/pol and HIV-2 gag gene products.

Kawamura, M, Shioda, T, Kitamura, T, Iwakura, Y, Shibuta, H

8th International Conference on AIDS Amsterdam, Netherlands, Jul 19, 1992
グレイマンガベイからのサル免疫不全ウイルス(SIV)の分離とその性状解析

朝長啓造, 片平じゅん, Hassan MA, 川村名子, 三浦智行, 速水正憲

日本獣医学会学術集会, Mar, 1991
Isolation of a highly divergent HIV-2 distinct from known isolates of HIV-2 and SIV.

Kawamura, M, Sakuragi, J, Fukasawa, M, Miura, T, Gojobori, T, Moriyama, E.N, Mingle, J.A.A, Netty, V.B.A, Hayami, M

6th International Conference on AIDS San Francisco, USA, Jun 20, 1990
Isolation and Characterization of HIV-2 from AIDS patient in Ghana

Ishikawa, K, Tsujimoto, H, Hasegawa, A, Miki, K, Mingle, J.A, Kawamura M, Hayami M

4th International Conference on ADIS Stockholm, Sweden1988, Jun 12, 1988
カモ由来ニューカッスル病ウイルスのニワトリヒナに対する病原性

川村名子

日本獣医学会学術集会, Mar, 1985

Teaching Experience

Professional Memberships

日本分子生物学会

Research Projects

遺伝子組み換えマウスの作製

科学研究費補助金, Apr, 2010 - Present
統合失調症関連遺伝子の探索と生化学的解析

科学技術振興調整費, Jun, 1998 - Mar, 2007
霊長類由来レトロウイルスの分子遺伝学

科学研究費補助金, Oct, 1987 - Mar, 1995
野生カモ類由来パラミキソウイルスのニワトリへの病原性と免疫原性について

科学研究費補助金, Apr, 1983 - Mar, 1985

Industrial Property Rights

特願2004-135667 血液を用いた統合失調症の診断方法

那波宏之, 染矢俊幸, 村竹辰之, 川村名子
特開2003-235557 精神分裂病により発現量が変化する遺伝子を規定する核酸を解析する方法

那波宏之, 高橋均, 入谷修司, 川村名子

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