論文

査読有り
2020年2月8日

Relationship between calcium intake and impaired activities of daily living in a Japanese population: NIPPON DATA90.

Journal of epidemiology
  • Mana Kogure
  • ,
  • Naho Tsuchiya
  • ,
  • Akira Narita
  • ,
  • Takumi Hirata
  • ,
  • Naoki Nakaya
  • ,
  • Tomohiro Nakamura
  • ,
  • Atsushi Hozawa
  • ,
  • Takehito Hayakawa
  • ,
  • Nagako Okuda
  • ,
  • Naoko Miyagawa
  • ,
  • Aya Kadota
  • ,
  • Takayoshi Ohkubo
  • ,
  • Yoshitaka Murakami
  • ,
  • Kiyomi Sakata
  • ,
  • Katsuyuki Miura
  • ,
  • Akira Okayama
  • ,
  • Tomonori Okamura
  • ,
  • Hirotsugu Ueshima

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.2188/jea.JE20190234

BACKGROUND: Major reasons for long-term care insurance certification in Japan are stroke, dementia and fracture. These diseases are reported to be associated with calcium intake. This study examined the association between calcium intake and impaired activities of daily living (ADL) using the data from NIPPON DATA90, consisting of representative sample of the Japanese population. METHODS: A population-based nested case control study was performed. A baseline survey was conducted in 1990, followed by ADL surveys of individuals ≥65 years old in 2000. Individuals with impaired ADL and selected age- and sex-matched controls were then identified. We obtained 132 pairs. Calcium intake was energy-adjusted using the residual method. The association between calcium intake and impaired ADL was examined using conditional logistic regression models. To assess the accuracy of the estimates, we conducted bootstrap analyses. RESULTS: The adjusted odds ratios (ORs) for impaired ADL compared with the group with a calcium intake of <476 mg/day were 0.72 (95% confidence interval, 95% CI: 0.37-1.40) for the 476-606 mg/day group and 0.44 (0.21-0.94) for the ≥607 mg/day group in 2000 (P for linear trend = 0.03). After the bootstrap analyses, the inverse relationship unchanged (median OR per 100-mg rise in calcium intake: 0.87 [1,000 resamplings], 95% CI: 0.76-0.97). CONCLUSIONS: After bootstrap analyses, calcium intake was inversely associated with impaired ADL, 10 years after the baseline survey.

リンク情報
DOI
https://doi.org/10.2188/jea.JE20190234
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32037365

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