張心儀 (Hsin'Yi Chang) - マイポータル

基本情報

所属: 京都大学大学院薬学研究科助教

学位: 理学博士

J-GLOBAL ID: 201701013581822613
researchmap会員ID: 7000019535

プロテオームに関する研究をしている。

論文

Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock

Jean-Michel Fustin, Rika Kojima, Kakeru Itoh, Hsin-Yi Chang, Ye Shiqi, Bowen Zhuang, Asami Oji, Shingo Gibo, Rajesh Narasimamurthy, David Virshup …

Proceedings of the National Academy of Sciences of the United States of America 115 5980-5985 2018年5月査読有り
Overexpression of miR-194 Reverses HMGA2-driven Signatures in Colorectal Cancer

Hsin-Yi Chang, Shu-Ping Ye, Shiow-Lin Pan, Tzu-Ting Kuo, Bia Chia Liu, Yi-Lin Chen, Tsui-Chin Huang

THERANOSTICS 7(16) 3889-3900 2017年査読有り
Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data

Chia-Lang Hsu, Hsin-Yi Chang, Jen-Yun Chang, Wen-Ming Hsu, Hsuan-Cheng Huang, Hsueh-Fen Juan

ONCOTARGET 7(24) 36293-36310 2016年6月査読有り
Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure

Kosaku Shinoda, Kana Ohyama, Yutaka Hasegawa, Hsin-Yi Chang, Mayu Ogura, Ayaka Sato, Haemin Hong, Takashi Hosono, Louis Z. Sharp, David W. Scheel …

CELL METABOLISM 22(6) 997-1008 2015年12月査読有り
Quantitative Proteomics Reveals Middle Infrared Radiation-Interfered Networks in Breast Cancer Cells

Hsin-Yi Chang, Ming-Hua Li, Tsui-Chin Huang, Chia-Lang Hsu, Shang-Ru Tsai, Si-Chen Lee, Hsuan-Cheng Huang, Hsueh-Fen Juan

JOURNAL OF PROTEOME RESEARCH 14(2) 1250-1262 2015年2月査読有り
Combination therapy targeting ectopic ATP synthase and 26S proteasome induces ER stress in breast cancer cells

H-Y Chang, T-C Huang, N-N Chen, H-C Huang, H-F J Juan

CELL DEATH & DISEASE 5(11) e1540 2014年11月査読有り
A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies

Wei-Jan Huang, Yen-An Tang, Mei-Yu Chen, Ying-Jan Wang, Fu-Han Hu, Tseng-Wei Wang, Shi-Wei Chao, Hui-Wen Chiu, Ya-Ling Yeh, Hsin-Yi Chang …

CANCER LETTERS 346(1) 84-93 2014年4月査読有り
Flow Cytometric Detection of Reactive Oxygen Species

Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan

Bio-protocol 3(8) e430 2013年4月査読有り
Flow Cytometric Detection of Mitochondrial Membrane Potential

Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan

Bio-protocol 3(8) e431 2013年4月査読有り
Middle Infrared Radiation Induces G(2)/M Cell Cycle Arrest in A549 Lung Cancer Cells

Hsin-Yi Chang, Meng-Her Shih, Hsuan-Cheng Huang, Shang-Ru Tsai, Hsueh-Fen Juan, Si-Chen Lee

PLOS ONE 8(1) e54117 2013年1月査読有り
Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response

Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan

CANCER RESEARCH 72(18) 4696-4706 2012年9月査読有り
Combination of RGD Compound and Low-Dose Paclitaxel Induces Apoptosis in Human Glioblastoma Cells

Ming-Wei Chang, Jem-Mau Lo, Hsueh-Fen Juan, Hsin-Yi Chang, Chun-Yu Chuang

PLOS ONE 7(5) 2012年5月査読有り
Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR

Tsui-Chin Huang, Hsin-Yi Chang, Cheng-Yu Chen, Pei-Yi Wu, Hsinyu Lee, Yung-Feng Liao, Wen-Ming Hsu, Hsuan-Cheng Huang, Hsueh-Fen Juan

FEBS LETTERS 585(22) 3582-3586 2011年11月査読有り
The effect of narrow bandwidth infrared radiation on the growth of Escherichia coli

Shang-Ru Tsai, Tsui-Chin Huang, Chia-Ming Liang, Hsin-Yi Chang, Yi-Tsung Chang, Hsuan-Cheng Huang, Hsueh-Fen Juan, Si-Chen Lee

APPLIED PHYSICS LETTERS 99(16) 163704 2011年10月査読有り
ATP13A2 Variability in Taiwanese Parkinson's Disease

Chiung-Mei Chen, Chih-Hsin Lin, Hsueh-Fen Juan, Fen-Ju Hu, Ya-Chin Hsiao, Hsin-Yi Chang, Chih-Ying Chao, I-Cheng Chen, Li-Ching Lee, Tsu-Wei Wang …

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 156B(6) 720-729 2011年9月査読有り
Targeting therapy for breast carcinoma by ATP synthase inhibitor aurovertin B

Tsui-Chin Huang, Hsin-Yi Chang, Chun-Hua Hsu, Wen-Hung Kuo, King-Jen Chang, Hsueh-Fen Juan

JOURNAL OF PROTEOME RESEARCH 7(4) 1433-1444 2008年4月査読有り
An apoptosis-related gene network induced by novel compound-cRGD in human breast cancer cells

Tsui-Chin Huang, Hsuan-Cheng Huang, Chih-Chin Chang, Hsin-Yi Chang, Chern-Han Ou, Chun-Hua Hsu, Shui-Tein Chen, Hsueh-Fen Juan

FEBS LETTERS 581(18) 3517-3522 2007年7月査読有り

書籍等出版物

Quantitative Proteome: The Isobaric Tags for Relative and Absolute Quantitation (iTRAQ)

Yi-Hsuan Wu, Hsueh-Fen Juan, Chia-Wei Hu, Chia-Lang Hsu, Chantal Hoi Yin Cheung, Hsin-Yi Chang, Wei-Hsuan Wang, Chen-Tsung Huang, Yu-Chao Wang, Chia-Hsien Lee, Hsuan-Cheng Huang (担当:分担執筆, 範囲:A Practical Guide To Cancer Systems Biology)

World Scientific 2018年1月
Proteomic Data Analysis: Functional Enrichment

Hsin-Yi Chang, Hsueh-Fen Juan (担当:分担執筆, 範囲:A Practical Guide to Cancer Systems Biology)

World Scientific Publishing 2018年1月
Transcriptome Analysis: Library Construction

Hsin-Yi Chang, Hsueh-Fen Juan (担当:分担執筆, 範囲:A Practical Guide to Cancer Systems Biology)

World Scientific Publishing 2018年1月
Chapter 15: Discovering drug targets for cancer therapy

Tsui-Chin Huang, Hsin-Yi Chang, Hsueh-Fen Juan (担当:分担執筆, 範囲:Systems Biology: Applications in cancer-related research)

World Scientific Publishing 2012年2月

講演・口頭発表等

高分離能nanoLC/MS/MSを用いた高深度ヒトプロテオーム解析

舟橋充央, 阿知波弘憲, 張心儀, 杉山直幸, 石濱泰

第25回クロマトグラフィーシンポジウム 2018年6月13日
Protein Chromatography for Bottom-Up Proteomics to Extend the Proteome Coverage

Kosuke Ogata, Michio Funahashi, Hsin-Yi Chang, Naoyuki Sugiyama, Yasushi Ishihama

66th ASMS Conference 2018年6月3日
キノームプロファイリングによるリン酸化ネットワーク解析

杉山直幸, 今村春菜, 坂本大, 中園純菜, 八児一隆, 高橋知里, Hsin-Yi, Chang・石濱泰

日本質量分析学会・日本プロテオーム学会 2018年合同大会 2018年5月18日
表面プロテオームプロファイルは脂肪細胞分類を反映する

張心儀, 杉山直幸, 石濱泰

日本質量分析学会・日本プロテオーム学会 2018年合同大会 2018年5月18日
Charge-Mounted Positional Separation by Ion Exchange Chromatography for Protein N-Terminal Peptide Enrichment

ChIh-Hsiang Chang, Eito Yamamoto, Hsin-Yi Chang, Naoyuki Sugiyama, Yasushi Ishihama

Mass Spectrometry and Proteomics 2018 (MSP2018) 2018年5月17日
キナーゼ基質大規模同定に基づくキナーゼの基質配列指向性評価

中園純菜, 坂本大, 張心儀, 杉山直幸, 石濱泰

日本質量分析学会・日本プロテオーム学会 2018年合同大会 2018年5月16日
チロシンキナーゼ特異的人工基質ペプチドを用いたin vitroキノーム活性計測

八児一隆, 高橋知里, 坂本大, 張心儀, 杉山直幸, 石濱泰

日本質量分析学会・日本プロテオーム学会 2018年合同大会 2018年5月16日
Suppression of CK2 Rewires the Metabolism toward Thermogenesis

Hsin-Yi Chang, Kosaku Shinoda, Shingo Kajimura, Yasushi Ishihama

The 7th Asia Oceania Mass Spectrometry Conference 2017年12月11日
Casein kinase 2 blockade rewires metabolism energetics toward thermogenesis in white adipocytes

Hsin-Yi Chang, Takashi Hosono, Ethan Pritikin, Kosaku Shinoda, Shingo Kajimura, Yasushi Ishihama

ConBio2017 2017年12月6日
Integrated Omics Reveals Metabolism Rewiring to Turn White Fat Brown

Hsin-Yi Chang

International Conference of Nutrition and Food Safety 2017年12月4日招待有り
Multi-omics analysis deciphers the CK2-subdued protein acetylations in promoting thermogenesis of white adipocytes

Hsin-Yi Chang, Kosaku Shinoda, Shingo Kajimura, Yasushi Ishihama

The 1st symposium of Kyoto Biomolecular Mass Spectrometry Society 2017年2月7日
Acetylateome analysis reveals carbon metabolism as a key factor enhancing thermogenesis in white adipocytes

Hsin-Yi Chang, Kosaku Shinoda, Shingo Kajimura, Yasushi Ishihama

The 15th HUPO World Congress 2016年9月18日
Comprehensive phosphoproteome analysis reveals acetylation-engaged enhancement of thermogenesis in white adipocytes

Hsin-Yi Chang, Kosaku Shinoda, Shingo Kajimura, Yasushi Ishihama

The 64th ASMS Conference 2016年6月5日
Combination Therapy Targeting Ectopic ATP Synthase and 26S Proteasome Induces ER Stress in Breast Cancer Cells

Hsin-Yi Chang, Nan-Ning Chen, Tsui-Chin Huang, Hsuan-Cheng Huang, Hsueh-Fen Juan

2014 TPS Translational and Systems Biology Symposium 2014年11月11日
Anti-tumor Effects of Middle Infrared Radiation on Breast Cancer Cells

Ming-Hua Li, Hsin-Yi Chang, Tsui-Chin Huang, Shang-Ru Tsai, Si-Chen Lee, Hsuan-Cheng Huang, Hsueh-Fen Juan

The 29th Joint Annual Conference of Biomedical Sciences 2014年3月15日
Ectopic ATP synthase: a Therapeutic Marker on Plasma Membrane in Lung Adenocarcinoma

Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan

The 18th Biophysics Conference 2013年6月27日
Proteome profiling identifies ATP synthase as a therapeutic biomarker on plasma membrane in lung adenocarcinoma

Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsueh-Fen Juan

Taiwan Proteomics Society International Conference: Recent Advances in Translational Medicine 2013年5月24日
Blocking ectopic ATP synthase suppresses lung adenocarcinoma cell growth by activating unfolded protein response

Hsueh-Fen Juan, Hsin-Yi Chang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, Hsuan-Cheng Huang

The 13th International Conference on Systems Biology 2012年8月19日
Revealing Novel Interacting Proteins of ATP Synthase by Human Proteome Microarray

Hui-Ting Tsai, Hsin-Yi Chang, Chien-Sheng Chen, Chun-Hua Hsu, Hsuan-Cheng Huang, Hsueh-Fen Juan

The 27th Joint Annual Conference of Biomedical Sciences 2012年3月17日
Investigation of Ectopic ATP synthase as a Therapeutic Marker in Lung Adenocarcinoma

Hsin-Yi Chang

The Fifth HOPE Meeting with Nobel Laureates 2012年2月26日

もっとみる

産業財産権

特許中華民國發明專利I379901 耐受醇類之大腸桿菌之製備方法

阮雪芬, 森浩禎, 張心儀, 黃宣誠, 黃翠琴, 廖俊智。