Miki Hino

Profile Information

Degree: 博士（農学）(東京大学)

Contact information: hinomikirikkyo.ac.jp
Other name(s) (e.g. nickname): 山本美紀（科研費登録氏名）
Researcher number: 40301783
J-GLOBAL ID: 201701020763140999
researchmap Member ID: 7000020099

Research Interests

Research Areas

Research History

Apr, 2022 - Present

College of Science Department of Life Science, Rikkyo University
Apr, 2017 - Mar, 2022

Assistant Professor, College of Science Department of Life Science, RIKKYO UNIVERSITY
Apr, 2012 - Mar, 2017

Researcher, College of Science Department of Life Science, RIKKYO UNIVERSITY

Education

Apr, 1984 - Mar, 1989

Faculty of Agriculture, The University of Tokyo

Papers

SPPL3-dependent downregulation of the synthesis of (neo)lacto-series glycosphingolipid is required for the staining of cell surface CD59

Kohei Kawaguchi, Miki Yamamoto-Hino, Satoshi Goto

Biochemical and Biophysical Research Communications, 571 81-87, Sep, 2021 Peer-reviewed
Subunits of the GPI transamidase complex localize to the endoplasmic reticulum and nuclear envelope in Drosophila

Kohei Kawaguchi, Miki Yamamoto‐Hino, Nina Matsuyama, Emiko Suzuki, Satoshi Goto

FEBS Letters, 595(7) 960-968, Apr, 2021 Peer-reviewed
Hrd1-dependent Degradation of the Unassembled PIGK Subunit of the GPI Transamidase Complex

Kohei Kawaguchi, Miki Yamamoto-Hino, Yoshiko Murakami, Taroh Kinoshita, Satoshi Goto

Cell Structure and Function, 46(2) 65-71, 2021 Peer-reviewedInvited
Lamin is essential for nuclear localization of the GPI synthesis enzyme PIG-B and GPI-AP production in Drosophila

Miki Yamamoto-Hino, Kohei Kawaguchi, Masaya Ono, Kazuhiro Furukawa, Satoshi Goto

Journal of Cell Science, 133(6), Jan 1, 2020 Peer-reviewedLead authorCorresponding author
Stability of the transamidase complex catalyzing GPI anchoring of proteins

Kohei Kawaguchi, Tatsuro Sato, Shu Kondo, Miki Yamamoto-Hino, Satoshi Goto

Biochemical and Biophysical Research Communications, 512(3) 584-590, May, 2019 Peer-reviewed
Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila.

Yamamoto-Hino M, Katsumata E, Suzuki E, Maeda Y, Kinoshita T, Goto S

Journal of Cell Science, 131(20), 2018 Peer-reviewed
Spatzle-Processing Enzyme-independent Activation of the Toll Pathway in Drosophila Innate Immunity

Miki Yamamoto-Hino, Satoshi Goto

CELL STRUCTURE AND FUNCTION, 41(1) 55-60, 2016 Peer-reviewed
Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing

Miki Yamamoto-Hino, Hideki Yoshida, Tomomi Ichimiya, Sho Sakamura, Megumi Maeda, Yoshinobu Kimura, Norihiko Sasaki, Kiyoko F. Aoki-Kinoshita, Akiko Kinoshita-Toyoda, Hidenao Toyoda …

GENES TO CELLS, 20(6) 521-542, Jun, 2015 Peer-reviewed
Dynamic regulation of innate immune responses in Drosophila by Senju-mediated glycosylation.

Miki Yamamoto-Hino, Masatoshi Muraoka, Shu Kondo, Ryu Ueda, Hideyuki Okano, Satoshi Goto

Proceedings of the National Academy of Sciences of the United States of America, 112(18) 5809-14, May 5, 2015 Peer-reviewed
In Vivo RNAi-Based Screens: Studies in Model Organisms

Miki Yamamoto-Hino, Satoshi Goto

GENES, 4(4) 646-665, Dec, 2013 Peer-reviewed
Identification of Proteasome Components Required for Apical Localization of Chaoptin Using Functional Genomics

Hiroyuki Yano, Miki Yamamoto-Hino, Wakae Awano, Kiyoko F. Aoki-Kinoshita, Kayoko Tsuda-Sakurai, Hideyuki Okano, Satoshi Goto

JOURNAL OF NEUROGENETICS, 26(1) 53-63, Mar, 2012 Peer-reviewed
Structure, function and formation of glycans in Drosophila

Yamamoto-Hino M, Okano H, Kanie O, Goto S

Glycans: Biochemistry, Characterization and Applications, 165-188, Feb 1, 2012 Peer-reviewed
Cisterna-specific Localization of Glycosylation-related Proteins to the Golgi Apparatus

Miki Yamamoto-Hino, Masato Abe, Takako Shibano, Yuka Setoguchi, Wakae Awano, Ryu Ueda, Hideyuki Okano, Satoshi Goto

CELL STRUCTURE AND FUNCTION, 37(1) 55-63, 2012 Peer-reviewed
Identification of Genes Required for Neural-Specific Glycosylation Using Functional Genomics

Miki Yamamoto-Hino, Yoshimi Kanie, Wakae Awano, Kiyoko F. Aoki-Kinoshita, Hiroyuki Yano, Shoko Nishihara, Hideyuki Okano, Ryu Ueda, Osamu Kanie, Satoshi Goto

PLOS GENETICS, 6(12) e1001254, Dec, 2010 Peer-reviewed
Autophagy-Dependent Rhodopsin Degradation Prevents Retinal Degeneration in Drosophila

Ryosuke Midorikawa, Miki Yamamoto-Hino, Wakae Awano, Yoshimi Hinohara, Emiko Suzuki, Ryu Ueda, Satoshi Goto

JOURNAL OF NEUROSCIENCE, 30(32) 10703-10719, Aug, 2010 Peer-reviewed
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

Akiko Mukai, Miki Yamamoto-Hino, Wakae Awano, Wakako Watanabe, Masayuki Komada, Satoshi Goto

EMBO JOURNAL, 29(13) 2114-2125, Jul, 2010 Peer-reviewed
Insight into the Regulation of Glycan Synthesis in Drosophila Chaoptin Based on Mass Spectrometry

Yoshimi Kanie, Miki Yamamoto-Hino, Yayoi Karino, Hiroki Yokozawa, Shoko Nishihara, Ryu Ueda, Satoshi Goto, Osamu Kanie

PLOS ONE, 4(5) e5434, May, 2009 Peer-reviewed
Spatial and temporal regulation of glycosylation during Drosophila eye development

Hiroyuki Yano, Miki Yamamoto-Hino, Satoshi Goto

CELL AND TISSUE RESEARCH, 336(1) 137-147, Apr, 2009 Peer-reviewed
N-glycosylation of the Drosophila neural protein Chaoptin is essential for its stability, cell surface transport and adhesive activity

Yu Hirai-Fujita, Miki Yamamoto-Hino, Osamu Kanie, Satoshi Goto

FEBS LETTERS, 582(17) 2572-2576, Jul, 2008 Peer-reviewed
Distinct functional units of the Golgi complex in Drosophila cells

H Yano, M Yamamoto-Hino, M Abe, R Kuwahara, S Haraguchi, Kusaka, I, W Awano, A Kinoshita-Toyoda, H Toyoda, S Goto

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(38) 13467-13472, Sep, 2005 Peer-reviewed

Misc.

Balanced ubiquitination determines cellular responsiveness to extracellular stimuli.

Mukai,A, Yamamoto-Hino,M, Komada.M, Okano,H, Goto,S

Cellular and Molecular Life Sciences, 69(23) 4007-4016, 2012 Peer-reviewedInvited
マススペクトロメトリー法によるショウジョウバエの糖タンパク質chaoptinの構造解析

蟹江善美, 日野美紀, 後藤聡, 蟹江治

日本糖質学会年会要旨集, 28th, 2008
マススペクトロメトリー法によるショウジョウバエの糖タンパク質の構造解析

蟹江善美, 日野美紀, 後藤聡, 蟹江治

日本糖質学会年会要旨集, 25th, 2005
Role of inositol 1,4,5-trisphosphate (IP3) receptor/Ca2+ signaling in cell function

K Mikoshiba, T Furuichi, A Miyawaki, T Michikawa, M Yamamoto-Hino, J Hirota, K Takei, T Inoue, S Kume, M Matsumoto …

CHALLENGES FOR NEUROSCIENCE IN THE 21ST CENTURY, 22(22) 121-146, 2000 Peer-reviewed
イオンチャネル研究の最前線イノシトール3リン酸受容体チャネルの構造と生理機能

道川貴章, 廣田順二, 山田麻紀, 日野美紀, 光山冬樹, 岩崎広英, 宮内浩, 岩附正人, 内山剛, 内田敬子 …

生化学, 71(8) 594-594, Aug, 1999
イオン性シグナル伝達の解明に挑むイオンチャネル構造機能研究の新展開 IP3受容体-IP3誘導Ca2+放出チャネルの構造機能と発現

古市貞一, 道川貴章, 吉川文生, 平嶋千恵, 水野秀昭, 内山剛, 岩附正人, 井上貴史, 廣田順二, 日野美紀

神経化学, 37(3) 261-261, Sep, 1998
チャネル/トランスポータタンパクの構造,機能,疾病 IP3レセプターCa放出チャネルとその病態

古市貞一, 吉川文生, 岩崎広英, 平嶋千恵, 水野秀昭, 内山剛, 井上貴史, 岩附正人, 松本峰男, 日野美紀

生化学, 70(8) 681-681, Aug, 1998
IP3 receptor

Mikoshiba K, Furuichi T, Michikawa T, Yamamoto-Hino M, Hirashima C, Mizuno H, Inoue T, Uchiyama T

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 43(12 Suppl) 1596-1602, 1998 Invited
Immuno-electron-microscopic localization of IP3 receptor in a rat submandibular gland conduit.

瀬川彰久, 日野美紀, 杉山友康, 長谷川護, 宮脇敦史, 古市貞一, 御子柴克彦, 安達栄治郎, 山科正平

日本電子顕微鏡学会学術講演会発表要旨集, 52nd, 1996

Research Projects

核ラミナの機能に必要な、新しい分子の発見

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, Apr, 2020 - Mar, 2023

山本美紀
Analysis of the mechanism of exacerbation of neurodegeneration by innate immunity

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Goto Satoshi
Mechanism of glycan change involved in the activation of innate immunity

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

YAMAMOTO(HINO) MIKI, GOTO Satoshi, KASE Sawako
自然炎症の恒常性維持に寄与する糖鎖修飾の解析

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2012 - Mar, 2014

山本美紀
GPI アンカー修飾は mRNA の局在によって制御されているか

科学研究費助成事業, 挑戦的萌芽研究, 日本学術振興会, Apr, 2011 - Mar, 2013
顎下腺の唾液分泌刺激における細胞内Ca^<2+>シグナリングの研究

科学研究費助成事業, 若手研究(B), 日本学術振興会, Apr, 2000 - Mar, 2001
顎下腺の唾液分泌刺激における細胞内Ca^<2+>シグナリングの研究

科学研究費助成事業, 奨励研究A, 日本学術振興会, Apr, 1999 - Mar, 2000

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