This study examined the impact of various forms of social capital drawn from social, cultural, and family resources on self-employment in the state of Hawaii. Data came from the U.S. 2000 Census involving all immigrants in Hawaii with particular interest given to the five Asian-immigrant groups (Japanese, Chinese, Korean, Filipino, and Vietnamese) aged between 18 and 65. The study found that social and cultural resources (i.e., presence of extended family, length of stay in the U.S., and ethnicity) and family resources (i.e., marital status, presence of children under 18 years of age, and number of children under 18 years of age) had a positive impact on the likelihood of self-employment. Finally, this study revealed that the role of social capital can enhance self-employment among immigrants in Hawaii.