菅野清彦 (KIYOHIKO SUGANO) - マイポータル

基本情報

所属: 立命館大学薬学部薬学科教授

学位: 薬学(2002年8月東邦大学)

J-GLOBAL ID: 201701003607475172
researchmap会員ID: 7000020423

研究キーワード

研究分野

ライフサイエンス / 薬系分析、物理化学 / 物理系薬学

経歴

2014年1月 - 2017年3月

東邦大学
2012年1月 - 2013年12月

旭化成ファーマ株式会社
2007年10月 - 2011年12月

Pfizer Inc (英国)
2004年4月 - 2007年9月

ファイザー株式会社
1995年4月 - 2004年3月

中外製薬株式会社

学歴

- 1995年3月

早稲田大学大学院, 理工学, 化学
- 1993年3月

早稲田大学, 理工学部, 化学科

主要な論文

Dissolution profiles of high-dose salt-form drugs in bicarbonate buffer and phosphate buffer.

Yuki Tarumi, Kiyohiko Sugano

Journal of pharmaceutical sciences 114(1) 477-485 2025年1月査読有り
A commentary on "Are all measures of liver Kpuu a function of FH, as determined following oral dosing, or have we made a critical error in defining hepatic drug clearance?".

Kiyohiko Sugano

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 198 106799 2024年7月査読有り
Drug Crystal Precipitation in Biorelevant Bicarbonate Buffer: A Well-Controlled Comparative Study with Phosphate Buffer.

Hibiki Yamamoto, Kiyohiko Sugano

Molecular pharmaceutics 21(6) 2854-2864 2024年6月査読有り責任著者
Dissolution Profiles of Immediate Release Products of Various Drugs in Biorelevant Bicarbonate Buffer: Comparison with Compendial Phosphate Buffer.

Nanami Okamoto, Masaki Higashino, Hibiki Yamamoto, Kiyohiko Sugano

Pharmaceutical research 41(5) 959-966 2024年5月査読有り責任著者
Comparison of Phosphate and Bicarbonate Buffer Solutions as Dissolution Test Media for Predicting Bioequivalence of Febuxostat Formulation.

Masaki Higashino, Kiyohiko Sugano

Chemical & pharmaceutical bulletin 72(11) 989-995 2024年査読有り
Dissolution Profiles of Oral Disintegrating Tablet with Taste Masking Granule Polymer Coating in Biorelevant Bicarbonate Buffer.

Masaki Higashino, Kiyohiko Sugano

Chemical & pharmaceutical bulletin 72(3) 298-302 2024年査読有り
Food and bile micelle binding of zwitterionic antihistamine drugs.

Rie Takeuchi, Kiyohiko Sugano

ADMET & DMPK 12(4) 649-656 2024年査読有り責任著者
Effect of Food Viscosity on Drug Dissolution.

Rika Hirose, Kiyohiko Sugano

Pharmaceutical research 41(1) 105-112 2024年1月査読有り責任著者
Bicarbonate buffer dissolution test with gentle mechanistic stress for bioequivalence prediction of enteric-coated pellet formulations.

Shotaro Ikuta, Hidetoshi Nakagawa, Toshiya Kai, Kiyohiko Sugano

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 192 106622 2024年1月査読有り
Dissolution Profiles of Carbamazepine Cocrystals with Cis-Trans Isomeric Coformers.

Omori Maaya, Yamamoto Hibiki, Matsui Fumiya, Sugano Kiyohiko

Pharmaceutical research 40(2) 579-591 2023年2月査読有り責任著者
Development of bicarbonate buffer flow-through cell dissolution test and its application in prediction of in vivo performance of colon targeting tablets.

Ikuta Shotaro, Nakagawa Hidetoshi, Kai Toshiya, Sugano Kiyohiko

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 180 106326 2023年1月査読有り
Thermodynamic Correlation between Liquid-Liquid Phase Separation and Crystalline Solubility of Drug-Like Molecules.

Uekusa Taiga, Watanabe Tomohiro, Watanabe Daiju, Sugano Kiyohiko

Pharmaceutics 14(12) 2022年11月査読有り招待有り
A Critical Overview of the Biological Effects of Excipients (Part II): Scientific Considerations and Tools for Oral Product Development.

Martinez Marilyn N, Wu Fang, Sinko Balint, Brayden David J, Grass Michael, Kesisoglou Filippos, Stewart Aaron, Sugano Kiyohiko

The AAPS journal 24(3) 61 2022年5月査読有り
Effect of divalent and trivalent metal ions on artificial membrane permeation of fluoroquinolones.

Nakatani Nanami, Sugano Kiyohiko

ADMET & DMPK 10(4) 289-297 2022年査読有り
Salt Solubility and Disproportionation - Uses and Limitations of Equations for pHmax and the In-silico Prediction of pHmax.

Avdeef Alex, Sugano Kiyohiko

Journal of pharmaceutical sciences 111(1) 225-246 2022年1月査読有り
Is equilibrium slurry pH a good surrogate for solid surface pH during drug dissolution?

Uekusa Taiga, Avdeef Alex, Sugano Kiyohiko

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 168 106037 2022年1月査読有り
Dissolution Kinetics of Nifedipine-Ionizable Polymer Amorphous Solid Dispersion: Comparison Between Bicarbonate and Phosphate Buffers.

Sakamoto Aoi, Sugano Kiyohiko

Pharmaceutical research 38(12) 2119-2127 2021年12月査読有り
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network.

Vinarov Zahari, Abrahamsson Bertil, Artursson Per, Batchelor Hannah, Berben Philippe, Bernkop-Schnürch Andreas, Butler James, Ceulemans Jens, Davies Nigel, Dupont Didier …

Advanced drug delivery reviews 171 289-331 2021年4月査読有り
Lost in modelling and simulation?

Sugano Kiyohiko

ADMET & DMPK 9(2) 75-109 2021年査読有り
Physicochemical and cell-based approach for early screening of phospholipidosis-inducing potential.

Tomizawa Kaori, Sugano Kiyohiko, Yamada Hiroshi, Horii Ikuo

The Journal of toxicological sciences 31(4) 315-24 2006年10月査読有り
High throughput solubility measurement with automated polarized light microscopy analysis.

Sugano Kiyohiko, Kato Teruhisa, Suzuki Kentaro, Keiko Kako, Sujaku Tetsujo, Mano Takashi

Journal of pharmaceutical sciences 95(10) 2115-22 2006年10月査読有り
Predicting Oral Absorption of Poorly Water-Soluble Drugs Using an Integrated System of a Miniscale Dissolution Test and Computer Simulation

Ryusuke Takano, Kiyohiko Sugano, Atsuko Higashida, Yoshiki Hayashi, Minoru Machida, Yoshinori Aso, Shinji Yamashita

Pharm.Res 23 1144-1156 2006年査読有り
Correction of permeability with pore radius of tight junctions in Caco-2 monolayers improves the prediction of the dose fraction of hydrophilic drugs absorbed by humans.

Saitoh Ryoichi, Sugano Kiyohiko, Takata Noriyuki, Tachibana Tatsuhiko, Higashida Atsuko, Nabuchi Yoshiaki, Aso Yoshinori

Pharmaceutical research 21(5) 749-55 2004年5月査読有り
Permeation characteristics of a hydrophilic basic compound across a bio-mimetic artificial membrane.

Sugano Kiyohiko, Nabuchi Yoshiaki, Machida Minoru, Asoh Yoshinori

International journal of pharmaceutics 275(1-2) 271-8 2004年5月査読有り
Biopharmaceutics classification by high throughput solubility assay and PAMPA.

Obata Kouki, Sugano Kiyohiko, Machida Minoru, Aso Yoshinori

Drug development and industrial pharmacy 30(2) 181-5 2004年2月査読有り
Prediction of passive intestinal absorption using bio-mimetic artificial membrane permeation assay and the paracellular pathway model.

Sugano Kiyohiko, Takata Noriyuki, Machida Minoru, Saitoh Kimitoshi, Terada Katsuhide

International journal of pharmaceutics 241(2) 241-51 2002年7月査読有り
Alkyl Radical Substitution on Disulfide in the Presence of Cobalt(II) Complexes

TADA Masaru, SUGANO Kiyohiko, YOSHIHARA Takao

Bulletin of the Chemical Society of Japan 68(10) 2969-2973 1995年10月15日査読有り
Alkyl Radical Substitution on Disulfide in the Presence of Cobalt(II) Complexes.

Tada Masaru, Sugano Kiyohiko, Yoshihara Takao

Bulletin of the Chemical Society of Japan 68(10) 2969-2973 1995年査読有り

もっとみる

MISC

医薬品原薬の摩擦帯電性評価

藤沼健太, 岡田翔太, 伊藤雅隆, 米持悦生, 菅野清彦, 寺田勝英

日本薬学会年会要旨集(CD-ROM) 136th(2) ROMBUNNO.28AB‐PM348S-281 2016年3月
Rate- and Extent-Limiting Factors of Oral Drug Absorption: Theory and Applications

Kiyohiko Sugano, Katsuhide Terada

Journal of Pharmaceutical Sciences 104(9) 2777-2788 2015年9月1日
Improving solubility with promiscuous multi -component drug crystals

Masataka Ito, Kiyohiko Sugano, Katsuhide Terada

European Pharmaceutical Review 20(5) 44-47 2015年
Passive lipoidal diffusion and carrier-mediated cell uptake are both important mechanisms of membrane permeation in drug disposition

Dennis Smith, Per Artursson, Alex Avdeef, Li Di, Gerhard F. Ecker, Bernard Faller, J. Brian Houston, Manfred Kansy, Edward H. Kerns, Stefanie D. Krämer …

Molecular Pharmaceutics 11(6) 1727-1738 2014年6月2日
Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications

Kiyohiko Sugano

Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications 2012年8月8日
Evidence-based approach to assess passive diffusion and carrier-mediated drug transport

Li Di, Per Artursson, Alex Avdeef, Gerhard F. Ecker, Bernard Faller, Holger Fischer, J. Brian Houston, Manfred Kansy, Edward H. Kerns, Stefanie D. Krämer …

Drug Discovery Today 17(15-16) 905-912 2012年8月
Aqueous boundary layers related to oral absorption of a drug: From dissolution of a drug to carrier mediated transport and intestinal wall metabolism

Kiyohiko Sugano

Molecular Pharmaceutics 7(5) 1362-1373 2010年10月4日
Coexistence of passive and carrier-mediated processes in drug transport

Kiyohiko Sugano, Manfred Kansy, Per Artursson, Alex Avdeef, Stefanie Bendels, Li Di, Gerhard F. Ecker, Bernard Faller, Holger Fischer, Grégori Gerebtzoff …

Nature Reviews Drug Discovery 9(8) 597-614 2010年8月
Introduction to computational oral absorption simulation

Kiyohiko Sugano

Expert Opinion on Drug Metabolism and Toxicology 5(3) 259-293 2009年3月
Solubility and dissolution profile assessment in drug discovery.

Kiyohiko Sugano, Arimichi Okazaki, Shohei Sugimoto, Sumitra Tavornvipas, Atsushi Omura, Takashi Mano

Drug metabolism and pharmacokinetics 22(4) 225-254 2007年8月

書籍等出版物

,Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications

Wiley 2012年8月20日

菅野清彦

基本情報

研究キーワード

研究分野

経歴

学歴

主要な論文

MISC

書籍等出版物

担当経験のある科目(授業)

所属学協会

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