論文

査読有り
2021年9月25日

Biomechanical Analysis of the Spine in Diffuse Idiopathic Skeletal Hyperostosis: Finite Element Analysis

Applied Sciences
  • Norihiro Nishida
  • Fei Jiang
  • Junji Ohgi
  • Masahiro Fuchida
  • Rei Kitazumi
  • Yuto Yamamura
  • Rui Tome
  • Yasuaki Imajo
  • Hidenori Suzuki
  • Masahiro Funaba
  • Xian Chen
  • Takashi Sakai
  • 全て表示

11
19
開始ページ
8944
終了ページ
8944
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.3390/app11198944
出版者・発行元
MDPI AG

Patients with diffuse idiopathic skeletal hyperostosis (DISH) develop fractures of the vertebral bodies, even in minor trauma, because of the loss of flexibility, which causes difficulties in fusing vertebrae; therefore, the diagnosis of spine injuries may be delayed. We used the three-dimensional finite element method to add data on ossification to the healthy vertebral model in order to investigate how stress in intervertebral discs changes with bone shape and whether these changes present any risk factors. A healthy spine model and a DISH flat model (T8–sacrum) were generated from medical images. As an ossified hypertrophic model, T11–T12 was cross-linked with hypertrophic ossification, and hypertrophy was found to be 5 and 10 mm. An ossifying hypertrophic groove model (5 and 10 mm) was created at T11–T12 and T11–L1. A groove was created at the center of T12, and the radius of curvature of the groove was set to 1 and 2.5 mm. An extension force and flexion force were applied to the upper part of T8, assuming that external forces in the direction of flexion and extension were applied to the spine. Stresses were greater in the DISH flat model than in the healthy model. In the hypertrophic ossification model, the stress on the vertebral body was similar to greater ossification in extension and flexion. In the ossified hypertrophic groove model, the stress at the center of the groove increased. In DISH, vertebrae are more susceptible to stress. Furthermore, depending on the morphology of ossification, stresses on the vertebrae and intervertebral discs differed even with similar loads. An examination of ossification geometry may help surgeons decide the thoracolumbar spine’s stress elevated position in patients with DISH, thereby contributing to the understanding of the pathogenesis of pain.

リンク情報
DOI
https://doi.org/10.3390/app11198944
URL
https://www.mdpi.com/2076-3417/11/19/8944/pdf
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85115853749&origin=inward 本文へのリンクあり
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85115853749&origin=inward
ID情報
  • DOI : 10.3390/app11198944
  • eISSN : 2076-3417
  • SCOPUS ID : 85115853749

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