2018年2月1日
Asymmetric Total Synthesis of (−)-Stemonamine and Its Stereochemical Stability
Chemistry - A European Journal
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- 巻
- 24
- 号
- 7
- 開始ページ
- 1539
- 終了ページ
- 1543
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1002/chem.201706057
- 出版者・発行元
- Wiley-VCH Verlag
The first asymmetric total synthesis of (−)-stemonamine is described. The key reactions included intramolecular acylation to construct the seven-membered ring and a tandem [2+2] cycloaddition-Dieckmann condensation reaction using an ynolate to form the fully substituted cyclopentenone moiety. Racemization and epimerization of the natural product were first experimentally demonstrated.
- ID情報
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- DOI : 10.1002/chem.201706057
- ISSN : 1521-3765
- ISSN : 0947-6539
- PubMed ID : 29276813
- SCOPUS ID : 85040697992