論文

2018年3月

Potentially inappropriate medications with polypharmacy increase the risk of falls in older Japanese patients: 1-year prospective cohort study

Geriatrics & gerontology international
  • Masumoto, Shoichi
  • ,
  • Sato, Mikiya
  • ,
  • Maeno, Takami
  • ,
  • Ichinohe, Yumiko
  • ,
  • Maeno, Tetsuhiro

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/ggi.13307

[AIM] We aimed to evaluate whether potentially inappropriate medications (PIMs) increase the risk for adverse clinical outcomes including falls, emergency department (ED) visits and unplanned hospitalizations in older Japanese patients with chronic diseases, comparing the difference between patients with and without polypharmacy.
[METHODS] A prospective observational cohort study was carried out in a Japanese outpatient primary care clinic. Baseline data was collected from January to March 2016. A total of 740 patients aged ≥65 years with chronic diseases were enrolled and were followed up at 1 year; falls, ED visits and unplanned hospitalizations were recorded. A questionnaire and review of the patients' medical records were used to collect information regarding sociodemographic status, comorbidities and medication prescriptions. PIMs were defined using the Screening Tool of Older Person's Prescriptions criteria version 2. Using logistic regression analysis, the incidence of falls, and ED visits and hospitalizations were compared between patients with and without PIMs, stratifying by number of prescriptions: those with five or more prescriptions and those with fewer than f

リンク情報
DOI
https://doi.org/10.1111/ggi.13307
ID情報
  • DOI : 10.1111/ggi.13307
  • ISSN : 1447-0594

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