higashimoto yuki

Profile Information

Affiliation: Senior Assistant Professor, School of Medical Sciences, Faculty of Medical Technology, Fujita Health University

Degree: 医学博士(藤田保健衛生大学)

Researcher number: 20569701
J-GLOBAL ID: 201801012069684307
researchmap Member ID: 7000023878

Research Interests

Research Areas

Research History

Apr, 2023 - Present

兼務課長, 臨床検査部, 藤田医科大学病院
Sep, 2021 - Present

School of Health Sciences Faculty of Medical Technology, Fujita Health University
Apr, 2017 - Present

藤田医科大学病院臨床検査部微生物遺伝子検査室兼務
Oct, 2018 - Aug, 2021

School of Health Sciences Faculty of Medical Technology, Fujita Health University
Apr, 2017 - Oct, 2018

Assistant Professor, Faculty of Medical Tecnology, Fujita Health University
Apr, 2009 - Mar, 2017

Medical Technologist, Department of Clinical Laboratory, Fujita Health University Hospital

Education

Apr, 2007 - Mar, 2009

臨床検査学領域, 保健学科, 藤田保健衛生大学大学院
Apr, 2004 - Mar, 2007

Fujita Health University

Awards

Papers

A GIRL WITH ADENOVIRUS TYPE 2 INDUCED INTERSTITIAL PNEUMONITIS ACUTELY EXACERBATED WITH PRIMARY HUMAN HERPESVIRUS 7 INFECTION.

Yoshiki Kawamura, Kei Kozawa, Goro Koinuma, Tetsuo Onda, Kazutoshi Cho, Yuki Higashimoto, Hiroki Miura, Tetsushi Yoshikawa

The Pediatric infectious disease journal, Feb 28, 2024
Similarities in rotavirus vaccine viral shedding and immune responses in pairs of twins.

Yasuko Enya, Hiroyuki Hiramatsu, Masaru Ihira, Ryota Suzuki, Yuki Higashimoto, Yusuke Funato, Kei Kozawa, Hiroki Miura, Masafumi Miyata, Yoshiki Kawamura …

Fujita medical journal, 9(3) 253-258, Aug, 2023
Changes in trends of pediatric β- and γ-herpesvirus infections during the COVID-19 pandemic: A single-center observational study.

Kei Kozawa, Yoshiki Kawamura, Fumihiko Hattori, Hiroki Miura, Yuki Higashimoto, Masaru Ihira, Masaaki Matsunaga, Atsuhiko Ota, Tetsushi Yoshikawa

Journal of medical virology, 95(7) e28925, Jul 6, 2023
Dry loop-mediated isothermal amplification assay for detection of SARS-CoV-2 from clinical specimens.

Yuki Higashimoto, Masaru Ihira, Yoshiki Kawamura, Masato Inaba, Kazuya Shirato, Tadaki Suzuki, Hideki Hasegawa, Tsutomu Kageyama, Yohei Doi, Tadayoshi Hata …

Fujita medical journal, 9(2) 84-89, May, 2023
6種のSARS-CoV-2抗原検査キットにおける性能評価

石田秀和, 稲垣薫乃, 長谷川瞳, 土井洋輝, 和久田光毅, 東本祐紀, 水谷謙明, 藤田孝, 竹村正男, 齋藤邦明 …

医療検査と自動化, 48(1) 75-80, Feb, 2023
Analysis of the reliability of rapid diagnostic tests for varicella, including breakthrough cases.

Yuki Higashimoto, Fumihiko Hattori, Yoshiki Kawamura, Kei Kozawa, Aoi Hamano, Mizuki Kato, Sayaka Kato, Asuka Hosokawa, Yasuko Enya, Masaru Ihira …

Journal of medical virology, 95(2) e28569, Feb, 2023
Correlation Between Rotavirus Antigenemia and Humoral Immune Response in Patients with Acute Rotavirus Gastroenteritis.

Yasuko Enya, Yoshiki Kawamura, Masaru Ihira, Fumihiko Hattori, Hidetaka Nakai, Naoko Nishimura, Takao Ozaki, Yuki Higashimoto, Kei Kozawa, Hiroki Miura …

The Pediatric infectious disease journal, 41(12) 1004-1006, Dec 1, 2022
Correlation between anti-S IgG and neutralizing antibody titers against three live SARS-CoV-2 variants in BNT162b2 vaccine recipients.

Yuki Higashimoto, Kei Kozawa, Hiroki Miura, Yoshiki Kawamura, Masaru Ihira, Hiroyuki Hiramatsu, Ryota Suzuki, Kei Haga, Reiko Takai-Todaka, Akihito Sawada …

Human vaccines & immunotherapeutics, 18(6) 2105611-2105611, Nov 30, 2022
Unremarkable antibody responses against various infectious agents after inoculation with the BNT162b2 COVID-19 vaccine.

Kei Kozawa, Hiroki Miura, Yoshiki Kawamura, Yuki Higashimoto, Masaru Ihira, Tetsushi Yoshikawa

Journal of medical virology, 94(10) 4583-4585, Oct, 2022
弾力的対応が可能な遺伝子検査システムの構築と運用

石田秀和, 東本祐紀, 水谷謙明, 長谷川瞳, 土井洋輝, 井平勝, 藤垣英嗣, 星雅人, 松浦秀哲, 仲本賢太郎 …

臨床検査, 66(7) 882-888, Jul, 2022
RV1接種後ワクチン株便中排泄と免疫誘導能の双生児間における類似性解析

井平勝, 塩谷泰子, 平松裕之, 鈴木竜太, 東本祐紀, 小澤慶, 河村吉紀, 河本聡志, 谷口孝喜, 吉川哲史

臨床とウイルス, 50(2) 126-126, May, 2022
Rotavirus incapable of NSP6 expression can cause diarrhea in suckling mice.

Saori Fukuda, Masanori Kugita, Yuki Higashimoto, Kazuya Shiogama, Hanako Tsujikawa, Kyoko Moriguchi, Naoto Ito, Makoto Sugiyama, Shizuko Nagao, Takayuki Murata …

The Journal of general virology, 103(5), May, 2022
Dynamics of salivary human herpesvirus-6 and -7 shedding in pregnant women.

Noriko Suzuki, Masaru Ihira, Yasuko Enya, Takahashi Yumi, Chisato Izuru, Igarashi Rie, Yuki Higashimoto, Miura Hiroki, Takanashi Asaki, Fujimoto Kaoru …

Journal of medical virology, 94(7) 3359-3367, Mar 4, 2022
Rotavirus genotypes and clinical outcome of natural infection based on vaccination status in the post-vaccine era.

Kei Kozawa, Yuki Higashimoto, Yoshiki Kawamura, Hiroki Miura, Takumi Negishi, Fumihiko Hattori, Masaru Ihira, Satoshi Komoto, Koki Taniguchi, Tetsushi Yoshikawa

Human vaccines & immunotherapeutics, 18(1) 1-7, Mar 3, 2022
Effect of Lactococcus lactis Strain Plasma on HHV-6 and HHV-7 Shedding in Saliva: A Prospective Observational Study.

Hiroki Miura, Masaru Ihira, Kei Kozawa, Yoshiki Kawamura, Yuki Higashimoto, Fumihiko Hattori, Tetsushi Yoshikawa

Microorganisms, 9(8), Aug 8, 2021
Diagnostic accuracy of LAMP versus PCR over the course of SARS-CoV-2 infection.

Masato Inaba, Yuki Higashimoto, Yoko Toyama, Tomoya Horiguchi, Masaya Hibino, Mitsunaga Iwata, Kazuyoshi Imaizumi, Yohei Doi

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 107 195-200, Jun, 2021
Evaluation of varicella vaccine effectiveness during outbreaks in schools or nurseries by cross-sectional study.

Yoshiki Kawamura, Fumihiko Hattori, Yuki Higashimoto, Kei Kozawa, Tetsushi Yoshikawa

Vaccine, 39(21) 2901-2905, May 18, 2021
Immune response against SARS-CoV-2 in pediatric patients including young infants.

Yoshiki Kawamura, Yuki Higashimoto, Hiroki Miura, Masaru Ihira, Masato Inaba, Ryota Ito, Kei Kozawa, Tetsushi Yoshikawa

Journal of medical virology, 93(3) 1776-1779, Mar, 2021 Peer-reviewed
Andrographolide, isolated from Andrographis paniculata , induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production.

Hiroki Doi, Taei Matsui, Johannes M Dijkstra, Atsushi Ogasawara, Yuki Higashimoto, Seiji Imamura, Tamae Ohye, Hiromu Takematsu, Itsuro Katsuda, Hidehiko Akiyama

F1000Research, 10 542-542, 2021
Trend in varicella patients 4 years after implementation of universal two-dose varicella vaccination in Japan.

Fumihiko Hattori, Kei Kozawa, Hiroki Miura, Yoshiki Kawamura, Yuki Higashimoto, Akiko Yoshikawa, Masaru Ihira, Tetsushi Yoshikawa

Vaccine, 38(46) 7331-7336, Oct 27, 2020 Peer-reviewed

Misc.

愛知県における小児でのSARS-CoV-2に対する抗体保有率の検討

小澤慶, 東本祐紀, 河村吉紀, 服部文彦, 中井英剛, 鈴木道雄, 西村直子, 尾崎隆男, 吉川哲史

臨床とウイルス, 51(3) 118-118, Sep, 2023
HHV-6B、HHV-7の血清疫学調査初感染年齢の年長化は本当か? 続報

東本祐紀, 小澤慶, 服部文彦, 河村吉紀, 井平勝, 鳥越貞義, 吉川哲史

臨床とウイルス, 51(3) 131-131, Sep, 2023
いまさら聞けないウイルス感染症診断における抗体検査の活用法

東本祐紀, 吉川哲史

Medical Technology, 51(8) 843-847, Aug, 2023
突発性発疹,最近の知見

鳥越貞義, 渡辺正博, 難波ひかる, 山田雅夫, 東本祐紀, 吉川哲史

日本小児科学会雑誌, 127(7) 1003-1003, Jul, 2023
【"よく遭遇する"質問を解決!ウィズコロナ時代の感染対策ベストアンサー9】知識編新型コロナウイルスとインフルエンザウイルスの検査

東本祐紀

INFECTION CONTROL, 32(5) 460-464, May, 2023
Retrospective immunohistochemical analysis of human cytomegalovirus infection in the placenta and its association with fetal growth restriction.

Yusuke Funato, Yuki Higashimoto, Yoshiki Kawamura, Yoshiko Sakabe, Minori Iwakura, Masaru Ihira, Kazuya Shiogama, Masafumi Miyata, Haruki Nishizawa, Takao Sekiya …

Fujita medical journal, 9(2) 90-94, May, 2023
6種のSARS-CoV-2抗原検査キットにおける性能評価

石田秀和, 稲垣薫乃, 長谷川瞳, 土井洋輝, 和久田光毅, 東本祐紀, 水谷謙明, 藤田孝, 竹村正男, 齋藤邦明 …

医療検査と自動化, 48(1) 75-80, Feb, 2023
イムノクロマト法によるSARS-CoV-2抗原定性検査キットの性能比較

稲垣薫乃, 石田秀和, 東本祐紀, 長谷川瞳, 土井洋輝, 和久田光毅, 水谷謙明, 藤田孝, 竹村正男, 齋藤邦明 …

日本臨床微生物学会雑誌, 33(Suppl.1) 241-241, Dec, 2022
乳のみマウスにおけるNSP6欠損ロタウイルスの増殖能および病原性の解析

福田佐織, 東本祐紀, 谷口孝喜, 河本聡志

臨床とウイルス, 50(4) 217-222, Oct, 2022
コロナ禍における検査技師の活躍現場を覗く! 藤田医科大学PCRセンターで奮闘する臨床検査技師

東本祐紀

Medical Technology, 50(10) 1146-1149, Oct, 2022
本学における新型コロナウイルス検査への取り組み

長谷川瞳, 石田秀和, 藤田孝, 東本祐紀, 藤垣英嗣, 秋山秀彦

日本医学検査学会抄録集, 71回 479-479, May, 2022
Clue cell形成に関与する各種細菌に着目した分子病理学的解析

原田隼兵, 平山将也, 三浦香里, 東本祐紀, 金子千之, 柳田隆正, 藤井多久磨, 堤寛, 安倍雅人, 塩竈和也

日本臨床細胞学会雑誌, 61(Suppl.1) 188-188, May, 2022
HHV-6B、HHV-7の血清疫学調査初感染年齢の年長化は本当か?

東本祐紀, 井平勝, 服部文彦, 小澤慶, 河村吉紀, 鳥越貞義, 吉川哲史

臨床とウイルス, 50(2) 143-143, May, 2022
アデノウイルス2型感染を契機に発症し、ヒトヘルペスウイルス7初感染を契機に急性増悪した特発性間質性肺炎の女児例

河村吉紀, 小澤慶, 東本祐紀, 井平勝, 吉川哲史

臨床とウイルス, 50(2) 145-145, May, 2022
RV1接種後ワクチン株便中排泄と免疫誘導能の双生児間における類似性解析

井平勝, 塩谷泰子, 平松裕之, 鈴木竜太, 東本祐紀, 小澤慶, 河村吉紀, 河本聡志, 谷口孝喜, 吉川哲史

臨床とウイルス, 50(2) 126-126, May, 2022
HHV-6B、HHV-7の血清疫学調査初感染年齢の年長化は本当か?

東本祐紀, 井平勝, 服部文彦, 小澤慶, 河村吉紀, 鳥越貞義, 吉川哲史

臨床とウイルス, 50(2) 143-143, May, 2022
アデノウイルス2型感染を契機に発症し、ヒトヘルペスウイルス7初感染を契機に急性増悪した特発性間質性肺炎の女児例

河村吉紀, 小澤慶, 東本祐紀, 井平勝, 吉川哲史

臨床とウイルス, 50(2) 145-145, May, 2022
Clue cell形成に関与する各種細菌に着目した分子病理学的解析

原田隼兵, 平山将也, 三浦香里, 東本祐紀, 金子千之, 柳田隆正, 藤井多久磨, 堤寛, 安倍雅人, 塩竈和也

日本臨床細胞学会雑誌, 61(Suppl.1) 188-188, May, 2022
本学における新型コロナウイルス検査への取り組み

長谷川瞳, 石田秀和, 藤田孝, 東本祐紀, 藤垣英嗣, 秋山秀彦

日本医学検査学会抄録集, 71回 479-479, May, 2022
【ウイルス研究に進歩をもたらした新しい技術】等温核酸増幅法loop-mediated isothermal amplification(LAMP)による迅速診断法開発水痘帯状疱疹ウイルス感染症診断における有用性

東本祐紀, 吉川哲史

臨床とウイルス, 50(1) 25-29, Mar, 2022

Books and Other Publications

ロタテックワクチン（RV5）接種後の便中ワクチンウイルス株排出の解析

東本祐紀, 井平勝, 三浦浩樹, 平松裕之, 鈴木竜太, 河本聡志, 谷口孝喜, 河村吉紀, 吉川哲史 (Role: Joint author)

臨床とウイルス, Oct, 2018
領域における臨床検査学入門第4版

東本祐紀 (Role: Contributor, 臨床免疫学)

KTC中央出版, Jul, 2018
血液培養システムの種類と特徴 Versa TREK®（バーサトレック）

早川敏、細田卓也、東本祐紀、和久田光毅 (Role: Joint author)

臨床と微生物, Sep, 2013

Teaching Experience

Apr, 2022 - Present

臨床病態解析学概論 (藤田医科大学大学院保健学研究科)
Apr, 2022 - Present

免疫学概論 (藤田医科大学大学院保健学研究科)
Apr, 2019 - Present

感染制御学概論 (藤田医科大学)
Apr, 2019 - Present

Assembly Education 3 (Fujita Health University)
Apr, 2017 - Present

生体防御学 (藤田保健衛生大学)
Apr, 2017 - Present

臨床微生物学 (藤田保健衛生大学)
Apr, 2017 - Present

臨床免疫学 (藤田保健衛生大学)
Apr, 2017 - Present

臨床微生物学実習 (藤田医科大学)
Apr, 2017 - Present

clinical immunity practice (Fujita Health University)
臨床病態学 (藤田保健衛生大学)

Professional Memberships

Research Projects

Development of a simple and rapid diagnostic method for using miRNA as a biomarker

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2022 - Mar, 2025
Elucidation of the role of HHV-6B infection in the development of medial temporal lobe epilepsy with hippocampal sclerosis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
Construction of health self-management system by developing hemoglobin measurement application

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
Development of a highly sensitive detection method for Central Nervous System infections using Droplet Digital PCR

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2020 - Mar, 2022

Yuki Higashimoto
Syndromic testing panel for central nervous system infections using the LAMP method

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2022

Ihira Masaru
医学研究・健康増進活動, 一般財団法人愛知健康増進財団

Dec, 2020 - Dec, 2021
Development of recombinant genital herpes vaccine based on the live attenuated rotavirus vaccine

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Yoshikawa Tetsushi
Development of discrimination between VZV vaccine strain and wild strain using Colorimetric LAMP

Fujita Health University, Apr, 2020 - Mar, 2021
ロタテック接種後のロタウイルスワクチン株の便中排出解析

H31年度医療科学部若手研究, 藤田医科大学, Apr, 2019 - Mar, 2020

東本祐紀
The point of care testing of herpesvirus infection by LAMP method

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Ihira Masaru
Digital Droplet PCR法を用いたヘルペスウイルス関連中枢神経疾患の高感度診断法の開発

H30年度医療科学部若手研究, 藤田保健衛生大学, Apr, 2018 - Mar, 2019

東本祐紀
非侵襲的検体採取検体を用いたLAMP法によるHHV-6B初感染迅速診断法の開発

平成29年度「研究奨励金」, 公益信託臨床検査医学研究振興基金, Feb, 2018 - Jan, 2019

東本祐紀
Development of a method for measuring HHV-6A and HHV-6B specific antibodies using synthetic peptides

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

Yuki Higashimoto
HHV-6 species specific serological assay

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2011 - 2013

HIGASHIMOTO Yuki, YOSHIKAWA Etsushi, IHIRA Masaru, ENOMOTO Yoshihiko, SUGIYAMA Hiroko

Profile Information

Research Interests

Research Areas

Research History

Education

Awards

Papers

Misc.

Books and Other Publications

Teaching Experience

Professional Memberships

Research Projects

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