論文

査読有り
2015年7月

New diterpenoids isolated from Stevia rebaudiana fermented by Saccharomyces cerevisiae

TETRAHEDRON LETTERS
  • Hitoshi Kamauchi
  • ,
  • Tatsuhiko Kon
  • ,
  • Kaoru Kinoshita
  • ,
  • Kazuhiko Takatori
  • ,
  • Kunio Takahashi
  • ,
  • Kiyotaka Koyama

56
29
開始ページ
4377
終了ページ
4382
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.tetlet.2015.05.092
出版者・発行元
PERGAMON-ELSEVIER SCIENCE LTD

Five new labdane-type diterpenoids, sterebins Q1 (1), Q2 (2), Q3 (3), Q4 (4), and R (5), were isolated from Stevia rebaudiana fermented by Saccharomyces cerevisiae. The structures of these compounds were established using NMR, MS, and IR methods and their absolute configurations were determined by the ECD spectra of their benzoate derivatives. Through the structures of these new compounds, it was established that the fermentation process caused selective epoxidation and nucleophilic addition of water. Thus, fermentation is an effective way to develop new natural resources for use as drug candidates by enhancing the diversity of natural compounds. (c) 2015 Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 4

リンク情報
DOI
https://doi.org/10.1016/j.tetlet.2015.05.092
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000357227300029&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.tetlet.2015.05.092
  • ISSN : 0040-4039
  • Web of Science ID : WOS:000357227300029

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