論文

査読有り
2015年4月

New sesquiterpenoids isolated from Atractylodes lancea fermented by marine fungus

TETRAHEDRON
  • Hitoshi Kamauchi
  • ,
  • Kaoru Kinoshita
  • ,
  • Kazuhiko Takatori
  • ,
  • Takashi Sugita
  • ,
  • Kunio Takahashi
  • ,
  • Kiyotaka Koyama

71
13
開始ページ
1909
終了ページ
1914
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.tet.2015.02.041
出版者・発行元
PERGAMON-ELSEVIER SCIENCE LTD

The diversity of natural compounds is extensive but not unlimited. Fermentation of rhizomes of Atractylodes lancea by marine fungus (Cladosporium cladosporioides) enhanced the diversity of natural compounds. From the fermented rhizomes of A. lancea, two new spirovetivane-type sesquiterpenoids, 2-oxo-12-hydroxy-hinesol (1) and 2-oxo-15-hydroxy-hinesol (2); a new guaiane-type sesquiterpenoid atractylol A (3); and three new eudesmane-type sesquiterpenoids, 14-hydroxy-isopterocarpolone (4), 3 alpha-hydroxy-pterocarpol (5), and (11R)-2, 11, 12-trihydroxy-beta-selinene (6), were isolated along with known sesquiterpenoids (7-10). The structures of these compounds were established using NMR, MS, and IR methods. These compounds (1-6) were not observed in A. lancea extracts by TLC and HPLC analysis, suggesting that these compounds were generated during the fermentation process. (C) 2015 Elsevier Ltd. All rights reserved.

Web of Science ® 被引用回数 : 19

リンク情報
DOI
https://doi.org/10.1016/j.tet.2015.02.041
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000352747900002&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.tet.2015.02.041
  • ISSN : 0040-4020
  • Web of Science ID : WOS:000352747900002

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