Apr, 2017 - Mar, 2020
Mathematical and physiological basis for high S/N ratio of rod photoreceptors
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
- Grant number
- 17K15156
- Japan Grant Number (JGN)
- JP17K15156
- Authorship
- Principal investigator
- Grant amount
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- (Total)
- 4,420,000 Japanese Yen
- (Direct funding)
- 3,400,000 Japanese Yen
- (Indirect funding)
- 1,020,000 Japanese Yen
- Grant type
- Competitive
Vertebrate rod and cone photoreceptors are responsible for scotopic and photopic vision, respectively. The light sensitivity and kinetics of there photoreceptors differ depending on their vison. The relationship between photoresponse properties and the phototransduction pathways and morphology in both photoreceptor cells remains unclear. To clarify this, we have created mouse models in which phototransduction molecules in rods are replaced with red cone opsin. In addition, the spatial model of photoreceptor cells revealed that the differences in photoreceptor morphology are involved in the photoresponse characteristics.
- Link information
- ID information
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- Grant number : 17K15156
- Japan Grant Number (JGN) : JP17K15156