論文

査読有り 国際誌
2021年6月9日

"Hybrid Lung Transplantation" Combining Living Donor and Cadaveric Lung Transplants: Report of 2 Cases.

Transplantation proceedings
  • Takeshi Kurosaki
  • ,
  • Takahiro Oto
  • ,
  • Shinji Otani
  • ,
  • Kentaroh Miyoshi
  • ,
  • Seiichiro Sugimoto
  • ,
  • Masaomi Yamane
  • ,
  • Shinichi Toyooka

記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.transproceed.2021.04.019

We present 2 cases of "hybrid lung transplant," which included sequentially implanting a living lobar graft to 1 side and a cadaveric graft to the other side. This procedure was approved by the institutional review board at Okayama University Hospital. The 2 recipients were diagnosed with severe idiopathic pulmonary fibrosis, and living donor lobar lung transplant was considered; however, 2 appropriate donors were not available. Therefore, we accepted extended criteria donor lungs with a partial pressure of oxygen/fraction of inspired oxygen ratio of <251 mm Hg. However, 1 of the 2 patients developed grade 2 primary graft dysfunction. The living donor lobar lung had a low volume but was in good condition, which contributed to the patient's recovery after primary graft dysfunction during the perioperative period. The other patient's status of bronchiolitis obliterans syndrome had gradually progressed to grade 3, and only the living donor lung was functioning at that time. However, both patients are alive 5.5 and 4.2 years after lung transplant, respectively. Hybrid lung transplantation may increase patients' chances of receiving transplants because patients are not likely to survive while waiting for ideal donor lungs to become available.

リンク情報
DOI
https://doi.org/10.1016/j.transproceed.2021.04.019
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34119337
ID情報
  • DOI : 10.1016/j.transproceed.2021.04.019
  • PubMed ID : 34119337

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